[domweek] DOM Week, December 19-23, 2022

[Department of Medicine weekly newsletter]

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DOM Week
December 16, 2022
News, information, and events of interest from the Department of Medicine <http://bit.ly/1TemKEY>

(If you have items for DOM week, please email amyf at uw.edu<mailto:amyf at uw.edu>)


Chair's Blog
Department Chair Dr. Barbara Jung has posted a new blog<https://bit.ly/3YAutY6> highlighting some of our achievements in 2022 and the progress we have made in implementing our departmental strategic plan.


Awards
Call for Nominations: John R. Pettit Endowed Leadership Award
Nominations are now being accepted for the annual John R. Pettit Endowed Leadership Award, which honors the long and varied service of its namesake. All nominations must be made by or before Jan. 31, via an online form<http://bit.ly/2GUJ7E4>. The award will be given out in the spring. The Pettit Award is open to professional staff members who are currently employed by UW Medicine. Preferred recipients will have five or more years of service at UW Medicine.

EDI news
Seeking new members to join our Gender Equity Council
The Gender Equity Council (GEC) is seeking new members! The GEC works to find areas of improvement related to gender equity and advise the Department of Medicine on ways to ensure an equitable workplace for faculty, trainees and staff. GEC terms are from 1-3 years and will include 6-8 meetings annually. Faculty, staff and trainees of all genders are welcome. Please reach out to Susan Merel<mailto:smerel at uw.edu> or Kelsey Griffin <mailto:kgriffin at medicine.washington.edu>  if you are interested or have questions.

To learn more about the charter and projects please visit our website<https://medicine.uw.edu/diversity/gender-equity>.

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Education news
[cid:image021.jpg at 01D9116E.E3028C10]Understanding and developing solutions to address health inequities
Dr. Anna Morenz, clinician researcher (General Internal Medicine) joined Collective Conversations<https://bit.ly/3it2GrM> to discuss her new role as a Health Systems and Policy Fellow. Collective Conversations is a series of discussions aimed at highlighting people and groups working to improve health through better health care systems.

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Innovations in Medical Education
The UW Center for Learning and Innovation in Medical education (CLIME) will sponsor 10 School of Medicine faculty, staff or students to attend the USC Keck School of Medicine Innovations in Medical Education virtual conference<https://bit.ly/3WiS0KU> on Feb. 16-17. The deadline to apply for CLIME to sponsor you<https://bit.ly/3Fx5a0h> is Dec. 23.


Research news
Global burden of cardiovascular disease
[cid:image022.jpg at 01D9116E.E3028C10]Cardiovascular disease (CVD) remains the leading cause of death across the globe, according to a new "almanac"-style special issue of the Journal of the American College of Cardiology. Dr. Gregory Roth, associate professor (Cardiology) is senior author on the new study that includes data from 204 countries and territories, highlighting the leading global modifiable cardiovascular risk factors, their contribution to disease burden and recent prevention advancements.

"Over 80% of cardiovascular disease is preventable," says Roth. "With this update, we are measuring some alarming global trends and reviewing the current interventions that can help countries make good, evidence-based choices for their health systems."

Learn more on our news site<https://bit.ly/3iZ68up>.

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Evergreen Fund Awardees
[cid:image023.jpg at 01D9116E.E3028C10]Research teams at Fred Hutchinson Cancer Center will receive in-house grants this year from the Evergreen Fund, a unique program to boost scientific projects deemed promising enough in their early stages to attract potential commercial partners later on.

Dr. Jim Boonyaratanakornkit, acting assistant professor (Allergy and Infectious Diseases) will receive a second Beyond Pilot grant to continue work that was boosted with a similar grant in 2020<https://www.fredhutch.org/en/news/center-news/2020/09/evergreen-fund-pilot-projects.html>. This year, his grant will help him and his team to enhance existing laboratory-designed antibodies, including those developed with the help of that first grant.
Another Beyond Pilot award winner this year is Dr. Kevin Cheung, associate professor (Medical Oncology), whose team is developing a monoclonal antibody drug to block necrosis, the formation of dead zones within a breast cancer tumor.

Dr. Stefan Radtke and colleagues, in collaboration with Dr. Hans-Peter Kiem, professor (Medical Oncology), will use their Beyond Pilot funding to develop further a suite of laboratory and clinical innovations that would help make possible "in vivo" gene therapies - where genetic changes are made inside the patient rather than in the lab - with the potential to cure HIV/AIDS and life-threatening blood disorders.

Dr. Roland Walter, professor (Hematology) and his team won a Beyond Pilot award for their project to develop a targeted radioimmunotherapy for adults with acute leukemia.

Graduate student Karthikeya Gottimukkala and Dr. Jennifer Adair, research associate professor (Medical Oncology), received Pilot funding for a project to develop a new generation of nanoparticles as vehicles for transporting molecular-scale gene-editing tools into human cells.

Learn more from Hutch News<https://bit.ly/3iSXRIu>.

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[https://www.seattlecca.org/sites/default/files/profiles/headshots/Appelbaum-primary.jpg]Dr. Jacob Appelbaum, acting instructor (Hematology) has received an American Society of Hematology (ASH) Scholar Award for his project "Negative impacts of myeloid targeting on anti- AML CAR T cell function." Since 1985, the ASH Scholar Award has helped ease the transition between training and the establishment of an independent career in hematology research by providing partial salary or other support during that critical period. Learn more on our news site<https://bit.ly/3FZTyEA>.

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[cid:image025.jpg at 01D9116E.E3028C10]The Cystic Fibrosis Foundation and Clinical Trials in Organ Transplant group have partnered and awarded Dr. Eric Morrell, assistant professor (Pulmonary, Critical Care and Sleep Medicine) a $200,000 grant to perform a proteomic analysis of existing lung and blood specimens from lung transplant recipients with a respiratory viral infection previously enrolled into CTOT. Collaborators include Ian Stanaway (Nephrology, Kidney Research Institute) and investigators from Duke University and UCLA.


Recent publications
Dr. Nancy Davidson, professor and head (Medical Oncology) wrote "In It for the Long Haul: Long-Term Benefit With Adjuvant Endocrine Therapy for Premenopausal Women With Early-Stage Steroid Receptor-Positive Breast Cancer<https://bit.ly/3hzThyD>" in the Journal of Clinical Oncology.

Dr. Mary (Nora) Disis, professor (Medical Oncology) is co-author of "Public Access to Scientific Research Findings and Principles of Biomedical Research-A New Policy for the JAMA Network<https://bit.ly/3BG53yo>" in JAMA.

Dr. Joshua Hill, associate professor (Allergy and Infectious Diseases) is senior author of "Infectious complications after intensive chemotherapy with CLAG-M versus 7+3 for AML and other high-grade myeloid neoplasms<https://go.nature.com/3VXVFhx>" in Leukemia. DOM co-authors are Anna Halpern, Kelda Schonhoff, Catherine Liu, Steven Pergam, Guang-Shing Cheng, Michael Boeckh, and Roland Walter.

Dr. Andrew Hsieh, associate professor (Medical Oncology) is senior author of "Defining cellular population dynamics at single-cell resolution during prostate cancer progression<https://bit.ly/3VRwHAt>" in eLife. DOM co-author is Peter Nelson. Learn more in "Tracking prostate cancer dynamics<https://bit.ly/3uOSTzg>" from Hutch News.

Dr. Linzee Mabrey, fellow, is lead author, and Dr. Mark Wurfel, professor (Pulmonary, Critical Care and Sleep Medicine) is senior author of "Plasma Interleukin-6 Predicts Clinical Decline After Completion of Dexamethasone Therapy in Severe COVID-19<https://bit.ly/3uXBnZH>" in Critical Care Explorations. DOM co-authors are Pavan Bhatraju, Eric Morrell, Leila Zelnick, Neha Sathe, Carmen Mikacenic, Thomas Martin, and W. Conrad Liles.

Dr. Ganesh Raghu, professor (Pulmonary, Critical Care and Sleep Medicine) is lead author of "Licensure laws and other barriers to telemedicine and telehealth: an urgent need for reform<https://bit.ly/3j9YXQr>" in The Lancet Respiratory Medicine.

Dr. Mazyar Shadman, associate professor (Medical Oncology) is senior author of "Zanubrutinib or Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia<https://bit.ly/3uKQshg>" in the New England Journal of Medicine.

Dr. Chaitra Ujjani, clinical associate professor (Medical Oncology) is lead author of "The Impact of B-Cell-Directed Therapy on Sars-Cov-2 Vaccine Efficacy in CLL: 1-Year Follow up<https://bit.ly/3W3Ez1H>" in Blood. DOM co-authors are Christina Poh, Sydney Lee, Mazyar Shadman, Ryan Lynch, Ajay Gopal, Edus Warren, Brian Till, Stephen Smith, Amy Sperling, and Joshua Hill.

Addition to last week: Drs. Jocelyn James, Nina Kim and Meena Ramchandani are collaborative authors on "Patient-centred models of hepatitis C treatment for people who inject drugs: a multicentre, pragmatic randomised trial<https://urldefense.com/v3/__https:/bit.ly/3iCMKTT__;!!K-Hz7m0Vt54!neswHC1T6lJCMfWnOJbt6fFVTfryFukizpl9KXqhHNH6HxS3iSC-wtRp4n5t88u95B2BATDLYOc83n1-hzAk$>" in the Lancet Gastroenterology & Hepatology.


In the news
Dr. Bradley Anawalt, professor (General Internal Medicine) is quoted in "Why Do Men Sprout Hairs in Weird Places With Age?<https://nyti.ms/3FTef4M>" in the New York Times.

Dr. Nisha Bansal, professor (Nephrology) joined the Medscape InDiscussion series to talk about "Primary Care Screening and Treatment of Chronic Kidney Disease<https://wb.md/3j5ABHs>".

Dr. Helen Chu, associate professor (Allergy and Infectious Diseases) is quoted in "Long COVID: a 'massive disabling event'<https://bit.ly/3VRCKFj>" in the Seattle Times and "It's time to wear a mask again, health experts say<https://nyti.ms/3UXvjes>" in the New York Times.

Dr. Mary (Nora) Disis, professor (Medical Oncology) is quoted in "Positive Moderna, Merck cancer vaccine data advances mRNA promise, shares rise<https://reut.rs/3hprYXG>" from Reuters.

Dr. Paul Pottinger, professor (Allergy and Infectious Diseases) is quoted in "Newest doctors shun infectious diseases specialty<https://n.pr/3UYprkY>" from NPR.


Weekly Calendar, December 19-23, 2022
Our events calendar is posted on our website<https://medicine.uw.edu/news/trumba-calendar>.

Coming up
Gender Equity Lunch Series: Mentoring and Trailblazing
On Wednesday, Jan. 25, 2023, 12-1pm, the inaugural recipients of our Gender Equity Awards in Mentorship and Trailblazing - Dr. Stephanie Page, professor and head (Metabolism, Endocrinology and Nutrition), Dr. Michi Shinohara, professor (Dermatology) and the Internal Medicine Residency staff - will talk about their work.

Led by guest moderators, the Gender Equity Lunch Series focuses on topics related to gender equity and leadership development. This series is open to all members of all genders in the Department of Medicine. Via Zoom<https://washington.zoom.us/j/92388076032>. Please register<https://forms.office.com/r/U5czH5CPeW> for this series.



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Amy Fields, Editor
amyf at uw.edu<mailto:amyf at uw.edu>


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