[domweek] DOM Week, April 14-18, 2025

[Department of Medicine weekly newsletter via domweek]

[cid:image001.jpg at 01DBAAF7.B80B6480]

DOM Week
April 11, 2025
News, information, and events of interest from the Department of Medicine

(if you have items for DOM Week, please email amyf at uw.edu<mailto:amyf at uw.edu>)


New UW Medicine intranet
[cid:image027.png at 01DBAAF8.7B9FC080]Vitals<https://bit.ly/3R3BNJc>, the new UW Medicine intranet, launched on April 9. It is a new platform for sharing important news and announcements. Please check this site for critical news, leadership messages, events, operational updates, community announcements, and more, as many critical updates will no longer be sent via email. There is also a mobile app<https://bit.ly/3E02dst>.


Staff news
[Jilian Angiulo]Staff spotlight: Jilian Angiulo
Our latest staff spotlight is on Julian Angiulo, program manager for the Adult Congenital Heart Disease program in the Division of Cardiology.

Learn more about her on our news site<https://bit.ly/4j38NgN>.

Faculty news
[Neelendu Dey]Dr. Neelendu Dey, associate professor (Gastroenterology) has been selected as the inaugural holder of the Kyle Thomas Spane Endowed Chair at Fred Hutch. This is the first community funded endowed chair at the Hutch. The chair supports a faculty member working in colon cancer prevention, early detection and emerging research opportunities.


Education news
Empowering resident autonomy
[David Rink]Resident training is rooted in the concept of graduated autonomy. This means that as residents gain more experience and demonstrate increasing competence, the level of supervision they receive is gradually reduced. However, this transition is not linear. It requires a dynamic balance between educators providing enough independence for residents to build confidence and competence while ensuring they are still adequately supported and supervised as they navigate the complexities of clinical practice.

In a recent article published in ATS Scholar<https://bit.ly/3R7g1UW>, lead author Dr. David Rink, internal medicine chief resident, shares his personal experiences and reflections on developing his professional identity during his training. Rink and his mentors, senior author Dr. Tyler Albert, associate professor, and co-author Dr. Gabrielle Berger, clinical associate professor (General Internal Medicine), combine their experience with an analysis of trainees' perceptions of autonomy and supervision to present a practical toolkit for empowering resident autonomy.

Read the full story on our news site<https://bit.ly/4i55Vih>.

________________________________

[cid:image031.jpg at 01DBAAF8.7B9FC080]2025 AΩA elections
The Alpha Omega Alpha (AΩA) Honor Medical Society's purpose is to perpetuate excellence in the medical profession. Election to AΩA is one of the highest honors that physicians can receive. It recognizes excellence in scholarly activities, humanistic qualities, leadership capacity, and exceptional patient care skills.

Congratulations to the newly elected residents and fellows this year: Joey Chiang, R3, Seattle IM residency program, Tom Enright, R3, Seattle IM residency program, Sajan Gill, fellow (Cardiology), Matthew Haley, fellow (Pulmonary, Critical Care and Sleep Medicine), Anika Kohlmeier, chief resident, Boise IM residency program, and Dan Olivieri, R3, Seattle IM residency program.

________________________________

UW Graduate Certificate in Palliative Care
Applications are now open for the University of Washington's Interprofessional Graduate Certificate in Palliative Care<https://bit.ly/4jgeyHG>. This 9-month virtual program is specifically designed for working professionals looking for additional training in palliative care communication, interprofessional practice, and system change. While some alumni work as members of specialty palliative care teams, most apply their skills as palliative care champions and change agents within their specialty. Apply by May 1 for priority admission. Upcoming virtual info sessions: April 22 and June 10, 4:30-5:30pm.


Research news
Everything is Tuberculosis
[Everything Is Tuberculosis by John Green (book cover)]About every 20 seconds, somebody dies from tuberculosis, a disease that has had an effective treatment since 1943. Despite the scientific advancement that has occurred to develop a vaccine for TB, understand its different forms, and how to diagnose and treat those forms, current improvement upon these facets has crept along slowly due to insufficient funding and attention.

The Seattle Tuberculosis Research Advancement Center<https://bit.ly/3E2TSUY> (SEATRAC) is changing this through their efforts to train the next generation of TB researchers and catalyze new research areas. SEATRAC recently hosted best-selling author John Green to discuss his new book "Everything is Tuberculosis."

The event was highlighted in The Daily<https://bit.ly/4cqEcHz>.

________________________________

Multiple myeloma is treatable, not curable. Is that set to change?
[Multiple myeloma cells]Multiple myeloma is cancer of the bone marrow; the "multiple" part refers to cancer cells that appear in various areas of the body as cancerous plasma cells overtake healthy blood cells.

For years, patients have been told that multiple myeloma is treatable but not curable. Yet data continues to accumulate about a subset of patients that remains disease-free for so many years that experts, including Drs. Rahul Banerjee, Andrew Cowan, and Philip Greenberg, are wondering if a cure may in fact be possible.

Some of the newer approaches include T-cell engagers, antibodies designed to guide immune system T cells to destroy cancerous cells, and CAR T-cell therapy, which similarly engineers T cells to seek out and kill identified cancer cells.

Read the full story from Hutch News<https://bit.ly/4lgPW3n>.

________________________________

What Influences Sleep Study Completion Among People with HIV in Care?
[Zainab Al-Tameemi]Led by Dr. Zainab Al-Tameemi, R3, the research project, "What Influences Sleep Study Completion Among People with HIV in Care?" has been accepted for presentation at Sleep 2025, the annual Associated Professional Sleep Societies (APSS) conference in Seattle in June. Drs. Vishesh Kapur, professor (Pulmonary, Critical Care and Sleep Medicine) and Stephanie Ruderman, research scientist (Allergy and Infectious Diseases) are collaborators on the project.

This is the first study to investigate characteristics associated with receiving sleep studies among people with HIV (PWH) engaged in care. Despite the high prevalence of obstructive sleep apnea and fatigue in this population, only 4% of nearly 4,000 PWH in their cohort had undergone a sleep study between 2008 and 2023. Those who did were more likely to have bothersome fatigue, better HIV control (higher CD4 counts and viral suppression), and more comorbidities like diabetes and hypertension.

Their novel findings have not been previously reported in the literature. Given that this population is both vulnerable and often underrepresented in sleep research, the researchers hope this work brings more attention to sleep health equity, encourages providers to recognize and prioritize this issue, and informs future efforts to improve access to care.

________________________________
[Pavan Bhatraju and Bill Altemeier]
Drs. Pavan Bhatraju, associate professor, and Bill Altemeier, professor (Pulmonary, Critical Care and Sleep Medicine) are Co-PIs on a four-year R01 from the National Heart, Lung, and Blood Institute (NHLBI) for their project "Targeting Angiopoietin-like 4 (ANGPTL4) in Severe Community Acquired Pneumonia". DOM co-investigators are Drs. Sina Gharib, Chi Hung, Gail Jarvik, Leila Zelnick, and Ian Stanaway.

The project will use a combination of clinical and pre-clinical translational research approaches to evaluate the role of ANGPTL4 in the host response to community-acquired pneumonia caused by both bacteria and viruses.


________________________________

[Andrew Portuguese]Dr. Andrew Portuguese, assistant professor (Hematology and Oncology) is PI on a study funded by Regeneron titled "An Exploratory Study Investigating the Tumor Microenvironment and Immune Cell Profiles in Plasmacytomas of Multiple Myeloma Patients Treated with Linvoseltamab." Co-I is Dr. Andrew Cowan.

BCMA-targeted bispecific antibodies (bsAbs) are a promising treatment for relapsed/refractory multiple myeloma, but they are less effective in patients with extramedullary disease (EMD). This study will analyze pre- and post-treatment biopsies from plasmacytomas to better understand how tumors and immune cells respond to linvoseltamab, a BCMA-targeted bsAb.

Using advanced multiplexed immunohistochemistry, they will examine the tumor microenvironment at high resolution to identify immune features linked to treatment response and resistance. Insights from this work may reveal why EMD is harder to treat and help guide future therapeutic strategies.


Recent publications
Dr. Bryan Kestenbaum, professor (Nephrology) is co-author of "Association of Clonal Hematopoiesis of Indeterminate Potential with Cardiovascular Events in Patients with CKD<https://bit.ly/42pswQV>" and "Clonal Hematopoiesis of Indeterminate Potential and Progression of CKD<https://bit.ly/3Rc6yLZ>" in the Journal of the American Society of Nephrology.

Dr. Sylvia LaCourse, associate professor (Allergy and Infectious Diseases) is co-author of "Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay<https://bit.ly/3FY7HnZ>" in Science Translational Medicine.

Dr. Megan Mayer, fellow (Pulmonary, Critical Care and Sleep Medicine) is senior author of "Should Medicaid Pay for Housing? Considering the Debate<https://bit.ly/42p906V>" in the Journal of General Internal Medicine.

Dr. Andrew Portuguese, assistant professor (Hematology and Oncology) is co-lead author of "A phase 1 trial of fully human BCMA CAR-T therapy for relapsed/refractory multiple myeloma with 5-year follow-up<https://bit.ly/4j26hYn>" in Blood. DOM co-authors are Andrew Cowan, Mazyar Shadman, Emily Liang, Brian Till, David Maloney, and Stanley Riddell.

Dr. Laura Pyle, research professor, Dr. Phoom Narongkiatikhun, postdoctoral scholar, Ye Ji Choi, research scientist, and Dr. Petter Bjornstad, professor (Metabolism, Endocrinology and Nutrition) are co-authors of "Unveiling mechanisms underlying kidney function changes during sex hormone therapy<https://bit.ly/3R8f1zU>" in the Journal of Clinical Investigation.

Dr. Ganesh Raghu, professor (Pulmonary, Critical Care and Sleep Medicine) is senior author of "Genomic classifier for usual interstitial pneumonia combined with bronchoalveolar lavage cellular profile: potential use in the clinical management of new onset ILD?<https://bit.ly/42AJ6NY>" in the European Respiratory Journal.

Dr. Mazyar Shadman, associate professor (Hematology and Oncology) is lead author of "Comparative efficacy of Bruton tyrosine kinase inhibitors in high-risk relapsed/refractory CLL: a network meta-analysis<https://bit.ly/42mBjD1>" in Blood Advances.

Dr. Lauge Sokol-Hessner, associate professor (General Internal Medicine) is lead author of "Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients During Clinical Care<https://bit.ly/42pTEPH>" in Agency for Healthcare Research and Quality. DOM co-author is Thomas Gallagher.


In the news
Dr. Larry Corey, professor (Allergy and Infectious Diseases) wrote "We Need an mRNA Champion in a Red Cape<https://bit.ly/4iXm36K>" for the Timmerman Report.

Dr. Julie Dombrowski, professor (Allergy and Infectious Diseases) is quoted in "CDC's top laboratory on sexually transmitted diseases is shut by Trump administration<https://bit.ly/3EdzCQw>" in STAT.

An obituary for Dr. King Holmes has been published in the New York Times<https://bit.ly/4j1lybJ>. Dr. Holmes was a long-standing leader in the Division of Allergy and Infectious Diseases.

Dr. Reena Mehra, professor and head (Pulmonary, Critical Care and Sleep Medicine) joined the ATS Breathe Easy Podcast to discuss "Rethinking Obstructive Sleep Apnea & Cardiovascular Risk<https://bit.ly/4lpI6oj>."

Dr. Anna Wald, professor and head (Allergy and Infectious Diseases) is quoted in "Does a Measles Infection Protect Against Cancer and Heart Disease? - HHS Secretary Robert F. Kennedy Jr. has claimed it does, but science says otherwise<https://bit.ly/3EnG7Qz>" in MedPage Today.


Events of interest
Medicine Grand Rounds
Dr. Ken Steinberg, professor (Pulmonary, Critical Care and Sleep Medicine) and vice chair for education, will present "Elevating and Sustaining Excellence in Education: The Role of a Vice Chair of Education" at Medicine Grand Rounds on Friday, April 18, 12-1pm, via zoom<https://washington.zoom.us/j/812197730>.

________________________________

Online AI training
Microsoft is providing an on-line training session for DOM employees to learn to create useful AI prompts on April 14, 12-1:30. If you are interested, please register<https://bit.ly/3YfVjWH> for the session.


Weekly Calendar, April 14-18, 2025
Our events calendar is posted on our website<https://medicine.uw.edu/news/trumba-calendar>.


Coming up
Resilience in Community
The UW Professional Staff Organization (PSO) Annual Forum<https://we.discover.uw.edu/NTI3LUFIUi0yNjUAAAGZulxUdxIESJrC-ik8E8mc473RtCtSkSvMiGWFhWEnuaXZ2Du9yHObdvEJSeEfXh4016769LY=> will be held virtually on April 22- 23. This year's theme, "Resilience in Community," acknowledges the uncertainty of our times and emphasizes the importance of cultivating a supportive, connected environment where we can learn from one another and grow together.

Women Faculty Day
The theme for Women Faculty Day this year is "Advocacy, Allyship, & Action: Building a Future for Women in Medicine & Science" and will feature UW Provost Dr. Tricia Serio as the Keynote Speaker. May 13, 9am-3:30pm, UW Center for Urban Horticulture Center. Please register for this event<https://bit.ly/3Dr2vs7>.


________________________________

Amy Fields, Editor
amyf at uw.edu<mailto:amyf at uw.edu>


[cid:image022.png at 01DBAAF7.B80B6480]<https://bit.ly/3WsMqs5>[cid:image023.jpg at 01DBAAF7.B80B6480]<http://www.facebook.com/UWDeptMedicine>[cid:image024.jpg at 01DBAAF7.B80B6480]<https://www.instagram.com/uwdeptmedicine/>[cid:image025.png at 01DBAAF7.B80B6480]<https://www.linkedin.com/company/department-of-medicine-university-of-washington/posts/?feedView=all>[cid:image026.png at 01DBAAF7.B80B6480]<http://www.youtube.com/uwdeptmedicine>


To subscribe/unsubscribe from this list, go to:
https://mailman1.u.washington.edu/mailman/listinfo/domweek


________________________________

Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, reproduce, distribute, disseminate or otherwise use this transmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of the message and any attachments.
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment.html>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image001.jpg
Type: image/jpeg
Size: 22120 bytes
Desc: image001.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image002.png
Type: image/png
Size: 283114 bytes
Desc: image002.png
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image004.jpg
Type: image/jpeg
Size: 25647 bytes
Desc: image004.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0001.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image006.jpg
Type: image/jpeg
Size: 13616 bytes
Desc: image006.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0002.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image008.jpg
Type: image/jpeg
Size: 14848 bytes
Desc: image008.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0003.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image010.jpg
Type: image/jpeg
Size: 2903 bytes
Desc: image010.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0004.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image012.jpg
Type: image/jpeg
Size: 20065 bytes
Desc: image012.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0005.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image014.jpg
Type: image/jpeg
Size: 50667 bytes
Desc: image014.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0006.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image016.jpg
Type: image/jpeg
Size: 10488 bytes
Desc: image016.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0007.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image018.jpg
Type: image/jpeg
Size: 26380 bytes
Desc: image018.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0008.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image020.jpg
Type: image/jpeg
Size: 31054 bytes
Desc: image020.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0009.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image022.png
Type: image/png
Size: 1238 bytes
Desc: image022.png
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0001.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image023.jpg
Type: image/jpeg
Size: 5443 bytes
Desc: image023.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0010.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image024.jpg
Type: image/jpeg
Size: 7566 bytes
Desc: image024.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0011.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image025.png
Type: image/png
Size: 1852 bytes
Desc: image025.png
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0002.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image026.png
Type: image/png
Size: 3421 bytes
Desc: image026.png
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0003.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image027.png
Type: image/png
Size: 7734 bytes
Desc: image027.png
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0004.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image028.jpg
Type: image/jpeg
Size: 1637 bytes
Desc: image028.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0012.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image029.jpg
Type: image/jpeg
Size: 1606 bytes
Desc: image029.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0013.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image030.jpg
Type: image/jpeg
Size: 1313 bytes
Desc: image030.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0014.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image031.jpg
Type: image/jpeg
Size: 1955 bytes
Desc: image031.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0015.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image032.jpg
Type: image/jpeg
Size: 2324 bytes
Desc: image032.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0016.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image033.jpg
Type: image/jpeg
Size: 4967 bytes
Desc: image033.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0017.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image034.jpg
Type: image/jpeg
Size: 1539 bytes
Desc: image034.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0018.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image035.jpg
Type: image/jpeg
Size: 2075 bytes
Desc: image035.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0019.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image036.jpg
Type: image/jpeg
Size: 1399 bytes
Desc: image036.jpg
URL: <http://mailman11.u.washington.edu/pipermail/domweek/attachments/20250411/5136e1cf/attachment-0020.jpg>