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<p class="MsoNormal" align="right" style="text-align:right"><span style="font-family:"Arial",sans-serif"><img width="209" height="51" style="width:2.177in;height:.5312in" id="Picture_x0020_40" src="cid:image001.jpg@01DBAAF7.B80B6480" alt=""></span><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal" align="right" style="text-align:right"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">DOM Week<o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">April 11, 2025<o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">News, information, and events of interest from the Department of Medicine<o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">(if you have items for DOM Week, please email
<a href="mailto:amyf@uw.edu"><span style="color:#39275B">amyf@uw.edu</span></a>) <o:p>
</o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">New UW Medicine intranet<o:p></o:p></span></b></p>
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</v:shapetype><v:shape id="Picture_x0020_4" o:spid="_x0000_s1035" type="#_x0000_t75" alt="""" style='position:absolute;margin-left:-16.5pt;margin-top:-178.6pt;width:51pt;height:49.9pt;z-index:251661312;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
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</v:shape><![endif]--><![if !vml]><img width="68" height="67" style="width:.7083in;height:.6979in" src="cid:image027.png@01DBAAF8.7B9FC080" align="left" hspace="12" alt="" v:shapes="Picture_x0020_4"><![endif]><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><a href="https://bit.ly/3R3BNJc"><span style="color:#39275B">Vitals</span></a>,
the new UW Medicine intranet, launched on April 9. It is a new platform for sharing important news and announcements. Please check this site for critical news, leadership messages, events, operational updates, community announcements, and more, as many critical
updates will no longer be sent via email. There is also a <a href="https://bit.ly/3E02dst">
<span style="color:#39275B">mobile app</span></a>. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Staff news<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="_x0000_s1034" type="#_x0000_t75" alt="Jilian Angiulo" style='position:absolute;margin-left:0;margin-top:253.3pt;width:36.75pt;height:50.35pt;z-index:251668480;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:left;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
<v:imagedata src="cid:image004.jpg@01DBAAF7.B80B6480" o:title="Jilian Angiulo" croptop="6409f" cropbottom="21148f" cropleft="14933f" cropright="13748f" />
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</v:shape><![endif]--><![if !vml]><img width="49" height="67" style="width:.5104in;height:.6979in" src="cid:image028.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="Jilian Angiulo" v:shapes="_x0000_s1034"><![endif]><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Staff
spotlight: Jilian Angiulo<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Our latest staff spotlight is on
<b>Julian Angiulo</b>, program manager for the Adult Congenital Heart Disease program in the Division of Cardiology.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Learn more about her on our
<a href="https://bit.ly/4j38NgN"><span style="color:#39275B">news site</span></a>.
<o:p></o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Faculty news<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_3" o:spid="_x0000_s1033" type="#_x0000_t75" alt="Neelendu Dey" style='position:absolute;margin-left:0;margin-top:.3pt;width:35.45pt;height:50.4pt;z-index:251660288;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
<v:imagedata src="cid:image006.jpg@01DBAAF7.B80B6480" o:title="Neelendu Dey" croptop="2671f" cropbottom="15815f" cropleft="8274f" cropright="7394f" />
<w:wrap type="square"/>
</v:shape><![endif]--><![if !vml]><img width="47" height="67" style="width:.4895in;height:.6979in" src="cid:image029.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="Neelendu Dey" v:shapes="Picture_x0020_3"><![endif]><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Neelendu Dey</b>, associate professor (Gastroenterology) has been selected as the inaugural holder of the Kyle Thomas Spane Endowed Chair at Fred Hutch. This is the first community funded endowed chair at the Hutch. The chair supports a faculty member working
in colon cancer prevention, early detection and emerging research opportunities. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Education news<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Empowering resident autonomy<o:p></o:p></span></b></p>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_2" o:spid="_x0000_s1032" type="#_x0000_t75" alt="David Rink" style='position:absolute;margin-left:0;margin-top:.35pt;width:33.15pt;height:43.2pt;z-index:251664384;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
<v:imagedata src="cid:image008.jpg@01DBAAF7.B80B6480" o:title="David Rink" croptop="2622f" cropbottom="27311f" cropleft="14477f" cropright="16912f" />
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</v:shape><![endif]--><![if !vml]><img width="44" height="58" style="width:.4583in;height:.6041in" src="cid:image030.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="David Rink" v:shapes="Picture_x0020_2"><![endif]><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Resident
training is rooted in the concept of graduated autonomy. This means that as residents gain more experience and demonstrate increasing competence, the level of supervision they receive is gradually reduced. However, this transition is not linear. It requires
a dynamic balance between educators providing enough independence for residents to build confidence and competence while ensuring they are still adequately supported and supervised as they navigate the complexities of clinical practice.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">In a recent article published in <a href="https://bit.ly/3R7g1UW"><span style="color:#39275B">ATS Scholar</span></a>, lead author Dr.
<b>David Rink</b>, internal medicine chief resident, shares his personal experiences and reflections on developing his professional identity during his training. Rink and his mentors, senior author Dr.
<b>Tyler Albert</b>, associate professor, and co-author Dr. <b>Gabrielle Berger</b>, clinical associate professor (General Internal Medicine), combine their experience with an analysis of trainees’ perceptions of autonomy and supervision to present a practical
toolkit for empowering resident autonomy. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Read the full story on our
<a href="https://bit.ly/4i55Vih"><span style="color:#39275B">news site</span></a>.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
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<hr size="1" width="100%" noshade="" style="color:#39275B" align="center">
</span></div>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_6" o:spid="_x0000_s1031" type="#_x0000_t75" alt="""" style='position:absolute;margin-left:0;margin-top:0;width:40.5pt;height:1in;z-index:251663360;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:left;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:line;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page' o:allowoverlap="f">
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</v:shape><![endif]--><![if !vml]><img width="54" height="96" style="width:.5625in;height:1.0in" src="cid:image031.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="" v:shapes="Picture_x0020_6"><![endif]><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">2025
AŁA elections<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The Alpha Omega Alpha (AŁA) Honor Medical Society’s purpose is to perpetuate excellence in the medical profession. Election to AŁA is one of the highest honors that physicians
can receive. It recognizes excellence in scholarly activities, humanistic qualities, leadership capacity, and exceptional patient care skills.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"> <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Congratulations to the newly elected residents and fellows this year:
<b>Joey Chiang</b>, R3, Seattle IM residency program<b>, Tom Enright</b>, R3, Seattle IM residency program<b>, Sajan Gill</b>, fellow (Cardiology),
<b>Matthew Haley</b>, fellow (Pulmonary, Critical Care and Sleep Medicine), <b>Anika Kohlmeier</b>, chief resident, Boise IM residency program, and
<b>Dan Olivieri</b>, R3, Seattle IM residency program. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<div class="MsoNormal" align="center" style="text-align:center"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">
<hr size="1" width="100%" noshade="" style="color:#39275B" align="center">
</span></div>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">UW Graduate Certificate in Palliative Care<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Applications are now open for the University of Washington’s
<a href="https://bit.ly/4jgeyHG"><span style="color:#39275B">Interprofessional Graduate Certificate in Palliative Care</span></a>. This 9-month virtual program is specifically designed for working professionals looking for additional training in palliative
care communication, interprofessional practice, and system change. While some alumni work as members of specialty palliative care teams, most apply their skills as palliative care champions and change agents within their specialty. Apply by
<b>May 1</b> for priority admission. Upcoming virtual info sessions: April 22 and June 10, 4:30-5:30pm.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Research news<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Everything is Tuberculosis<o:p></o:p></span></b></p>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_8" o:spid="_x0000_s1030" type="#_x0000_t75" alt="Everything Is Tuberculosis by John Green (book cover)" style='position:absolute;margin-left:0;margin-top:.05pt;width:47.65pt;height:1in;z-index:251666432;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
<v:imagedata src="cid:image012.jpg@01DBAAF7.B80B6480" o:title="Everything Is Tuberculosis by John Green (book cover)" />
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</v:shape><![endif]--><![if !vml]><img width="64" height="96" style="width:.6666in;height:1.0in" src="cid:image032.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="Everything Is Tuberculosis by John Green (book cover)" v:shapes="Picture_x0020_8"><![endif]><span style="font-family:"Arial",sans-serif;mso-ligatures:none">About
every 20 seconds, somebody dies from tuberculosis, a disease that has had an effective treatment since 1943.<span style="color:black;background:white"> Despite the scientific advancement that has occurred to develop a vaccine for TB, understand its different
forms, and how to diagnose and treat those forms, current improvement upon these facets has crept along slowly due to insufficient funding and attention.
</span><span style="background:white"><o:p></o:p></span></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;background:white;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The
<a href="https://bit.ly/3E2TSUY"><span style="color:#39275B">Seattle Tuberculosis Research Advancement Center</span></a> (SEATRAC) is changing this through their efforts to train the next generation of TB researchers and catalyze new research areas. SEATRAC
recently hosted best-selling author John Green to discuss his new book “Everything is Tuberculosis.”
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The event was highlighted in
<a href="https://bit.ly/4cqEcHz"><span style="color:#39275B">The Daily</span></a>.
<o:p></o:p></span></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></b></p>
<div class="MsoNormal" align="center" style="text-align:center"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">
<hr size="1" width="100%" noshade="" style="color:#39275B" align="center">
</span></div>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Multiple myeloma is treatable, not curable. Is that set to change?<o:p></o:p></span></b></p>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_1" o:spid="_x0000_s1029" type="#_x0000_t75" alt="Multiple myeloma cells" style='position:absolute;margin-left:0;margin-top:5.9pt;width:100.6pt;height:78pt;z-index:251659264;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
<v:imagedata src="cid:image014.jpg@01DBAAF7.B80B6480" o:title="Multiple myeloma cells" />
<w:wrap type="square"/>
</v:shape><![endif]--><![if !vml]><img width="134" height="104" style="width:1.3958in;height:1.0833in" src="cid:image033.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="Multiple myeloma cells" v:shapes="Picture_x0020_1"><![endif]><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Multiple
myeloma is cancer of the bone marrow; the “multiple” part refers to cancer cells that appear in various areas of the body as cancerous plasma cells overtake healthy blood cells.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">For years, patients have been told that multiple myeloma is treatable but not curable. Yet data continues to accumulate about a subset of patients that remains disease-free
for so many years that experts, including Drs. <b>Rahul Banerjee</b>, <b>Andrew Cowan</b>, and
<b>Philip Greenberg</b>, are wondering if a cure may in fact be possible.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Some of the newer approaches include T-cell engagers, antibodies designed to guide immune system T cells to destroy cancerous cells, and CAR T-cell therapy, which similarly
engineers T cells to seek out and kill identified cancer cells. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Read the full story from
<a href="https://bit.ly/4lgPW3n"><span style="color:#39275B">Hutch News</span></a>.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<div class="MsoNormal" align="center" style="text-align:center"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">
<hr size="1" width="100%" noshade="" style="color:#39275B" align="center">
</span></div>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><a name="_Hlk195079117"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">What Influences Sleep Study Completion Among People with HIV in Care?<o:p></o:p></span></b></a></p>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_5" o:spid="_x0000_s1028" type="#_x0000_t75" alt="Zainab Al-Tameemi" style='position:absolute;margin-left:0;margin-top:.3pt;width:45.9pt;height:50.4pt;z-index:251662336;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
<v:imagedata src="cid:image016.jpg@01DBAAF7.B80B6480" o:title="Zainab Al-Tameemi" cropleft="5852f" />
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</v:shape><![endif]--><![if !vml]><img width="61" height="67" style="width:.6354in;height:.6979in" src="cid:image034.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="Zainab Al-Tameemi" v:shapes="Picture_x0020_5"><![endif]><span style="mso-bookmark:_Hlk195079117"></span><span style="mso-bookmark:_Hlk195079117"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Led
by Dr. <b>Zainab Al-Tameemi</b>, R3, the research project, “What Influences Sleep Study Completion Among People with HIV in Care?” has been accepted for presentation at Sleep 2025, the annual Associated Professional Sleep Societies (APSS) conference in Seattle
in June. Drs. Vishesh Kapur, professor (Pulmonary, Critical Care and Sleep Medicine) and Stephanie Ruderman, research scientist (Allergy and Infectious Diseases) are collaborators on the project.
<o:p></o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk195079117"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk195079117"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">This is the first study to investigate characteristics associated with receiving sleep studies among people with HIV (PWH) engaged
in care. Despite the high prevalence of obstructive sleep apnea and fatigue in this population, only 4% of nearly 4,000 PWH in their cohort had undergone a sleep study between 2008 and 2023. Those who did were more likely to have bothersome fatigue, better
HIV control (higher CD4 counts and viral suppression), and more comorbidities like diabetes and hypertension.<o:p></o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk195079117"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>
<p class="MsoNormal"><span style="mso-bookmark:_Hlk195079117"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Their novel findings have not been previously reported in the literature. Given that this population is both vulnerable and often underrepresented
in sleep research, the researchers hope this work brings more attention to sleep health equity, encourages providers to recognize and prioritize this issue, and informs future efforts to improve access to care.<o:p></o:p></span></span></p>
<span style="mso-bookmark:_Hlk195079117"></span>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<div class="MsoNormal" align="center" style="text-align:center"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">
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</span></div>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_9" o:spid="_x0000_s1027" type="#_x0000_t75" alt="Pavan Bhatraju and Bill Altemeier" style='position:absolute;margin-left:0;margin-top:12.7pt;width:33.4pt;height:93.6pt;z-index:251667456;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
<v:imagedata src="cid:image018.jpg@01DBAAF7.B80B6480" o:title="Pavan Bhatraju and Bill Altemeier" />
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</v:shape><![endif]--><![if !vml]><img width="45" height="125" style="width:.4687in;height:1.302in" src="cid:image035.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="Pavan Bhatraju and Bill Altemeier" v:shapes="Picture_x0020_9"><![endif]><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Drs.
<b>Pavan Bhatraju</b>, associate professor, and <b>Bill Altemeier</b>, professor (Pulmonary, Critical Care and Sleep Medicine) are Co-PIs on a four-year R01 from the National Heart, Lung, and Blood Institute (NHLBI) for their project “Targeting Angiopoietin-like
4 (ANGPTL4) in Severe Community Acquired Pneumonia”. DOM co-investigators are Drs. Sina Gharib, Chi Hung, Gail Jarvik, Leila Zelnick, and Ian Stanaway.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The project will use a combination of clinical and pre-clinical translational research approaches to evaluate the role of ANGPTL4 in the host response to community-acquired
pneumonia caused by both bacteria and viruses.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<div class="MsoNormal" align="center" style="text-align:center"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">
<hr size="1" width="100%" noshade="" style="color:#39275B" align="center">
</span></div>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="_x0000_s1026" type="#_x0000_t75" alt="Andrew Portuguese" style='position:absolute;margin-left:0;margin-top:-.25pt;width:36.25pt;height:50.4pt;z-index:251665408;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>
<v:imagedata src="cid:image020.jpg@01DBAAF7.B80B6480" o:title="Andrew Portuguese" cropbottom="26136f" cropleft="23105f" cropright="24156f" />
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</v:shape><![endif]--><![if !vml]><img width="48" height="67" style="width:.5in;height:.6979in" src="cid:image036.jpg@01DBAAF8.7B9FC080" align="left" hspace="12" alt="Andrew Portuguese" v:shapes="_x0000_s1026"><![endif]><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Andrew Portuguese</b>, assistant professor (Hematology and Oncology) is PI on a study funded by Regeneron titled “An Exploratory Study Investigating the Tumor Microenvironment and Immune Cell Profiles in Plasmacytomas of Multiple Myeloma Patients Treated
with Linvoseltamab.” Co-I is Dr. Andrew Cowan.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">BCMA-targeted bispecific antibodies (bsAbs) are a promising treatment for relapsed/refractory multiple myeloma, but they are less effective in patients with extramedullary
disease (EMD). This study will analyze pre- and post-treatment biopsies from plasmacytomas to better understand how tumors and immune cells respond to linvoseltamab, a BCMA-targeted bsAb.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Using advanced multiplexed immunohistochemistry, they will examine the tumor microenvironment at high resolution to identify immune features linked to treatment response and
resistance. Insights from this work may reveal why EMD is harder to treat and help guide future therapeutic strategies.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Recent publications<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Bryan Kestenbaum</b>, professor (Nephrology) is co-author of “<a href="https://bit.ly/42pswQV"><span style="color:#39275B">Association of Clonal Hematopoiesis of Indeterminate Potential with Cardiovascular Events in Patients with CKD</span></a>” and “<a href="https://bit.ly/3Rc6yLZ"><span style="color:#39275B">Clonal
Hematopoiesis of Indeterminate Potential and Progression of CKD</span></a>” in the Journal of the American Society of Nephrology.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Sylvia LaCourse</b>, associate professor (Allergy and Infectious Diseases) is co-author of “<a href="https://bit.ly/3FY7HnZ"><span style="color:#39275B">Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay</span></a>”
in Science Translational Medicine. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Megan Mayer</b>, fellow (Pulmonary, Critical Care and Sleep Medicine) is senior author of “<a href="https://bit.ly/42p906V"><span style="color:#39275B">Should Medicaid Pay for Housing? Considering the Debate</span></a>” in the Journal of General Internal
Medicine.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Andrew Portuguese</b>, assistant professor (Hematology and Oncology) is co-lead author of “<a href="https://bit.ly/4j26hYn"><span style="color:#39275B">A phase 1 trial of fully human BCMA CAR-T therapy for relapsed/refractory multiple myeloma with 5-year
follow-up</span></a>” in Blood. DOM co-authors are Andrew Cowan, Mazyar Shadman, Emily Liang, Brian Till, David Maloney, and Stanley Riddell.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Laura Pyle</b>, research professor, Dr. <b>Phoom Narongkiatikhun</b>, postdoctoral scholar,
<b>Ye Ji Choi</b>, research scientist, and Dr. <b>Petter Bjornstad</b>, professor (Metabolism, Endocrinology and Nutrition) are co-authors of “<a href="https://bit.ly/3R8f1zU"><span style="color:#39275B">Unveiling mechanisms underlying kidney function changes
during sex hormone therapy</span></a>” in the Journal of Clinical Investigation.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Ganesh Raghu</b>, professor (Pulmonary, Critical Care and Sleep Medicine) is senior author of “<a href="https://bit.ly/42AJ6NY"><span style="color:#39275B">Genomic classifier for usual interstitial pneumonia combined with bronchoalveolar lavage cellular
profile: potential use in the clinical management of new onset ILD?</span></a>” in the European Respiratory Journal.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Mazyar Shadman</b>, associate professor (Hematology and Oncology) is lead author of “<a href="https://bit.ly/42mBjD1"><span style="color:#39275B">Comparative efficacy of Bruton tyrosine kinase inhibitors in high-risk relapsed/refractory CLL: a network meta-analysis</span></a>”
in Blood Advances. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Lauge Sokol-Hessner</b>, associate professor (General Internal Medicine) is lead author of “<a href="https://bit.ly/42pTEPH"><span style="color:#39275B">Making Healthcare Safer IV: Programs for Responding to Harms Experienced by Patients During Clinical
Care</span></a>” in Agency for Healthcare Research and Quality. DOM co-author is Thomas Gallagher.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">In the news<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Larry Corey</b>, professor (Allergy and Infectious Diseases) wrote “<a href="https://bit.ly/4iXm36K"><span style="color:#39275B">We Need an mRNA Champion in a Red Cape</span></a>” for the Timmerman Report.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Julie Dombrowski</b>, professor (Allergy and Infectious Diseases) is quoted in “<a href="https://bit.ly/3EdzCQw"><span style="color:#39275B">CDC’s top laboratory on sexually transmitted diseases is shut by Trump administration</span></a>” in STAT.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">An obituary for Dr.
<b>King Holmes</b> has been published in the <a href="https://bit.ly/4j1lybJ"><span style="color:#39275B">New York Times</span></a>. Dr. Holmes was a long-standing leader in the Division of Allergy and Infectious Diseases.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Reena Mehra</b>, professor and head (Pulmonary, Critical Care and Sleep Medicine) joined the ATS Breathe Easy Podcast to discuss “<a href="https://bit.ly/4lpI6oj"><span style="color:#39275B">Rethinking Obstructive Sleep Apnea & Cardiovascular Risk</span></a>.”<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Anna Wald</b>, professor and head (Allergy and Infectious Diseases) is quoted in “<a href="https://bit.ly/3EnG7Qz"><span style="color:#39275B">Does a Measles Infection Protect Against Cancer and Heart Disease? — HHS Secretary Robert F. Kennedy Jr. has claimed
it does, but science says otherwise</span></a>” in MedPage Today. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Events of interest<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Medicine Grand Rounds<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.
<b>Ken Steinberg</b>, professor (Pulmonary, Critical Care and Sleep Medicine) and vice chair for education, will present “Elevating and Sustaining Excellence in Education: The Role of a Vice Chair of Education” at Medicine Grand Rounds on Friday,
<b>April 18</b>, 12-1pm, <a href="https://washington.zoom.us/j/812197730"><span style="color:#39275B">via zoom</span></a>.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<div class="MsoNormal" align="center" style="text-align:center"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">
<hr size="1" width="100%" noshade="" style="color:#39275B" align="center">
</span></div>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Online AI training<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Microsoft is providing an on-line training session for DOM employees to learn to create useful AI prompts on
<b>April 14</b>, 12-1:30. If you are interested, please <a href="https://bit.ly/3YfVjWH">
<span style="color:#39275B">register</span></a> for the session. <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Weekly Calendar, April 14-18, 2025<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Our events calendar is posted on
</span><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><a href="https://medicine.uw.edu/news/trumba-calendar"><span style="color:#39275B">our website</span></a></span><span style="font-family:"Arial",sans-serif;mso-ligatures:none">.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"> <o:p></o:p></span></p>
<p class="MsoNormal"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Coming up<o:p></o:p></span></u></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Resilience in Community<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The UW Professional Staff Organization (PSO)
</span><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><a href="https://we.discover.uw.edu/NTI3LUFIUi0yNjUAAAGZulxUdxIESJrC-ik8E8mc473RtCtSkSvMiGWFhWEnuaXZ2Du9yHObdvEJSeEfXh4016769LY=" target="_blank"><span style="color:#39275B">Annual Forum</span></a></span><span style="font-family:"Arial",sans-serif;mso-ligatures:none">
will be held virtually on </span><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">April 22-</span></b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">
</span><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">23</span></b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">. This year’s theme, “Resilience in Community,” acknowledges the uncertainty of our times and emphasizes the
importance of cultivating a supportive, connected environment where we can learn from one another and grow together.<o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Women Faculty Day<o:p></o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The theme for Women Faculty Day this year is “Advocacy, Allyship, & Action: Building a Future for Women in Medicine & Science<i>”</i> and will feature UW Provost Dr. Tricia
Serio as the Keynote Speaker. </span><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">May 13</span></b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">, 9am-3:30pm, UW Center for Urban Horticulture Center. Please
</span><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><a href="https://bit.ly/3Dr2vs7"><span style="color:#39275B">register for this event</span></a></span><span style="font-family:"Arial",sans-serif;mso-ligatures:none">.
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Amy Fields, Editor
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</span><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><a href="mailto:amyf@uw.edu"><span style="color:#39275B">amyf@uw.edu</span></a></span><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">To subscribe/unsubscribe from this list, go to:
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