[domweek] DOM Week, January 2-6, 2023

[Department of Medicine weekly newsletter]

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DOM Week
December 30, 2022
News, information, and events of interest from the Department of Medicine <http://bit.ly/1TemKEY>

(If you have items for DOM week, please email amyf at uw.edu<mailto:amyf at uw.edu>)


2022 year in review
Most viewed Medicine News stories
We are sharing our top 10 most viewed stories of 2022 from our News Site<https://bit.ly/3VBmiIa>:


  1.  Say my name: The importance of name pronunciation<https://mednews.uw.edu/news/say-my-name> (Geetanjali Chander, Başak Çoruh, Barbara Jung, Genevieve Pagalilauan)
  2.  Celebrating top doctors<https://mednews.uw.edu/news/top-docs-2022>
  3.  Living with an aging mind: Personal, philosophical and practical considerations<https://mednews.uw.edu/news/living-with-aging-mind> (Barak Gaster)
  4.  Faculty Spotlight: Melissa Robinson<https://mednews.uw.edu/news/faculty-spotlight-melissa-robinson>
  5.  A partnership to train physician scientists<https://mednews.uw.edu/news/uw-msm-mstp> (Mary-Claire King, Marshall Horwitz, Robb MacLellan)
  6.  Faculty Spotlight: Başak Çoruh<https://mednews.uw.edu/faculty-spotlight-basak-coruh>
  7.  Faculty Spotlight: Rotonya Carr<https://mednews.uw.edu/news/faculty-spotlight/carr>
  8.  Staff Spotlight: Kelsey Griffin<https://mednews.uw.edu/news/staff-spotlight-kelsey-griffin>
  9.  Staff Spotlight: Ayushi Gupta<https://mednews.uw.edu/news/staff-spotlight-ayushi-gupta>
  10. Ringing in 2022<https://mednews.uw.edu/news/blog/2022> (Barbara Jung)


Most viewed Newsroom stories
Members of the Department of Medicine are included in over half (14 of 22) of the top  news stories in 2022 from UW Medicine Newsroom:


  *   Breast cancer vaccine safely generates anti-tumor immunity<https://newsroom.uw.edu/news/breast-cancer-vaccine-safely-generates-anti-tumor-immunity> (Nora Disis)
  *   Patients with rare skin cancer face 40% recurrence rate<https://newsroom.uw.edu/news/patients-rare-skin-cancer-face-40-recurrence-rate> (Paul Nghiem)
  *   Viral shedding ebbs over time with HSV-1 genital infections<https://newsroom.uw.edu/news/viral-shedding-ebbs-over-time-hsv-1-genital-infections> (Christine Johnston, Sarah Gunby, Lichen Jing, Victoria Campbell, David Koelle and Anna Wald)
  *   In memoriam: Deborah Nickerson, genome pioneer<https://newsroom.uw.edu/news/memoriam-deborah-nickerson-genome-pioneer> (Mary-Claire King and Gail Jarvik are two of the co-authors who wrote this tribute)
  *   2nd opinion lets ex-Husky QB bypass open heart surgery<https://newsroom.uw.edu/postscript/2nd-opinion-lets-ex-husky-qb-bypass-open-heart-surgery> (Bill Lombardi)
  *   Home-based flu tests comparable to clinical testing<https://newsroom.uw.edu/news/home-based-flu-tests-comparable-clinical-testing> (Helen Chu is co-author on the paper related to this story)
  *   Study: 'Mix-and-match' booster strategy is safe, effective<https://newsroom.uw.edu/news/study-mix-and-match-booster-strategy-safe-effective> (Christine Johnston, Tia Babu, Julie McElrath)
  *   Adding key foods to a diet will help restore gut health<https://newsroom.uw.edu/postscript/adding-key-foods-diet-will-help-restore-gut-health> (Chris Damman)
  *   Rapid antigen tests accurately detect COVID variants<https://newsroom.uw.edu/postscript/rapid-antigen-tests-accurately-detect-covid-variants> (Paul Drain)
  *   Paxlovid? Evusheld? Discussing COVID therapeutics<https://newsroom.uw.edu/resource/paxlovid-evusheld-discussing-covid-therapeutics> (Shireesha Dhannireddy)
  *   Butyrate in microbiome abates a host of ills, studies find<https://newsroom.uw.edu/postscript/butyrate-microbiome-abates-host-ills-studies-find> (Chris Damman)
  *   Cardiologists are 1st to use tool to remove tumor from heart<https://newsroom.uw.edu/news/cardiologists-are-1st-use-tool-remove-tumor-heart> (James McCabe, Zachary Steinberg, and David Elison)
  *   Second-generation COVID-19 vaccine clinical trial starts<https://newsroom.uw.edu/news/second-generation-covid-19-vaccine-clinical-trial-starts> (Anna Wald and Tia Babu)
  *   Patient receives region's 1st DCD heart transplant<https://newsroom.uw.edu/news/patient-receives-regions-1st-dcd-heart-transplant> (Dan Fishbein)

Most viewed Hutch News Stories
We are featured in three of the ten top-read scientific news articles published in 2022 from Hutch News:

  *   Testing cord blood transplants as a cure for leukemia - and HIV<https://www.fredhutch.org/en/news/center-news/2022/03/hiv-cure-cord-blood.html> (Filippo Milano and Hans-Peter Kiem)
  *   Test of a new 'germline-targeting' HIV vaccine prepares to launch<https://www.fredhutch.org/en/news/center-news/2022/05/hiv-vaccine-germline-stamatatos.html> (Larry Corey and Julie McElrath)
  *   At Fred Hutch, a Novel Approach to Immunotherapy Is Helping Keith Lang Beat Back Merkel Cell Carcinoma<https://www.seattlecca.org/story/at-fred-hutch-a-novel-approach-to-immunotherapy-is-helping-keith-lang-beat-back-merkel-cell> (Shailender Bhatia)

Popular Huddle stories of 2022
We are featured in two of the top ten most viewed stories from the Huddle:

  *   Get to Know: Anneliese Schleyer, Interim Chief Medical Officer<https://bit.ly/3NCrBUM>
  *   Gaining perspective on Life During the Pandemic From Astrophotography<https://bit.ly/3we1NrS> (Sina Gharib)



Education news
Call for applications
The VA Puget Sound Health Services Research and Development (HSR&D) Center of Innovation for Veteran-Centered and Value-Driven Care Post-Doctoral (MD) Fellowship is accepting applications through Feb. 1, 2023. The two-year fellowship combines a mentored research experience with professional development and didactic training in Learning Health System research competencies with a goal of training the next generation of VA- and/or University-based physician investigators in health services and health disparities research. Interested applicants should email Erica Tartaglione<mailto:Erica.Tartaglione at va.gov>. More information can be found on the VA website<https://www.seattledenvercoin.research.va.gov/Fellowship/MDFellowship.asp>.


Research news
Targeting tau, the other protein behind Alzheimer's disease
[cid:image013.jpg at 01D91C6C.F05E5520]In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to be able to affect the course of this relentless, incurable disease. But many researchers believe that for any treatment to have a major impact on the course of Alzheimer's, they will also have to target a second protein that to date has not received as much attention as beta-amyloid, a protein called tau.

"The amyloid plaques start the disease cascade, so it makes sense to try to eliminate them, but it's tau that kills the cells," said Dr. Brian Kraemer, research professor (Gerontology and Geriatric Medicine). In an article published this week in PNAS<https://bit.ly/3VwSOLo>, researchers report the identification of a protein that appears to be crucial in forming abnormal collections of tau. The scientists showed that by blocking the gene required for the production of the protein it is possible to prevent the accumulation of tau in an animal model.

Read the full story from UW Medicine Newsroom<https://bit.ly/3VzpEeK>.


Recent publications
Dr. Alwiya Ahmed, R3, is co-author of "Trends in Labor Unionization Among US Health Care Workers, 2009-2021<https://bit.ly/3C8qAjv>" in JAMA.

Dr. James Andrews, assistant professor (Rheumatology) is lead author of "Appendicular Lean Mass, Grip Strength, and the Incidence of Dementia among Older Adults in the Health ABC Study<https://bit.ly/3jyfSMH>" in the Journals of Gerontology. DOM co-authors are May Reed, Jose Garcia and Paul Crane.

Joshua Bis, Jennifer Brody, Dr. Bruce Psaty, and Colleen Sitlani (General Internal Medicine) are co-authors of "Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies<https://go.nature.com/3vot5u9>" in Nature Genetics.

Dr. Justin Bullock, fellow (Nephrology) is co-author of "Opportunities and challenges in discussing racism during primary care visits<https://bit.ly/3I4QCaV>" in Health Services Research.

Dr. Noam Kopmar, fellow, is lead author and Dr. Ryan Cassaday, associate professor (Hematology) is senior author of "How I Prevent and Treat Central Nervous System Disease in Adults with Acute Lymphoblastic Leukemia<https://bit.ly/3G0iOcE>" in Blood.

Dr. Graham Nichol, professor (General Internal Medicine) is co-author of "Effect of COVID-19 Vaccine Messaging Platforms in Emergency Departments on Vaccine Acceptance and Uptake: A Cluster Randomized Clinical Trial<https://bit.ly/3PY1hWR>" in JAMA Internal Medicine.

Dr. Elizabeth Phelan, professor (Gerontology and Geriatric Medicine) is senior author of "Provider knowledge, beliefs, and self-efficacy to deprescribe opioids and sedative-hypnotics<https://bit.ly/3X3rPZp>" in the Journal of the American Geriatrics Society.

Dr. Andrew Portuguese, fellow (Hematology) is lead author, and Dr. Christopher Blosser, clinical professor (Nephrology) is senior author of "CD19 CAR-T therapy in solid organ transplant recipients: case report and systematic review<https://go.nature.com/3VvLobk>" in Bone Marrow Transplantation. DOM co-authors are Jordan Gauthier, Scott Tykodi, Evan Hall, and Alexandre Hirayama.

Dr. Scott Ramsey, professor (General Internal Medicine) is lead author of "Economic Analysis of Screening, Diagnostic, and Treatment Technologies for Cancer: Reflections and a Roadmap for Prospective Authors<https://bit.ly/3RQLVDd>" in the Journal of Clinical Oncology.


In the news
Dr. Rotonya Carr, associate professor and head (Gastroenterology) talked to UW Medicine Newsroom in "Dry January's lasting health impacts<https://bit.ly/3Q8EkjR>."

Breast cancer vaccine research by Dr. Mary (Nora) Disis, professor (Medical Oncology) and her team was among the "most interesting, wondrous & hopeful" science news stories this month on Oregon Public Broadcasting<https://bit.ly/3YTYpyt>.

Dr. Mayumi Endo, clinical assistant professor (Metabolism, Endocrinology and Nutrition) is quoted in "Common Thyroid Issues That Can Look Like Menopause<https://bit.ly/3Wn93fw>" from Right as Rain.

Dr. Mary-Claire King, professor (Medical Genetics) is quoted in "In memoriam: Female trailblazers who leapt over barriers to fight for their sisters<https://n.pr/3GwXxsA>" from NPR.

Dr. Klaus Mergener, affiliate professor (Gastroenterology) is quoted in "Top bariatric surgery news in 2022: Exploring trends in gastric bypass, sleeve gastrectomy<https://bit.ly/3Ij42Ax>" in Healio Gastroenterology.


Weekly Calendar, January 2-6, 2023
Our events calendar is posted on our website<https://medicine.uw.edu/news/trumba-calendar>.


Coming up
Gender Equity Lunch Series: Mentoring and Trailblazing
On Wednesday, Jan. 25, 2023, 12-1pm, the inaugural recipients of our Gender Equity Awards in Mentorship and Trailblazing - Dr. Stephanie Page, professor and head (Metabolism, Endocrinology and Nutrition), Dr. Michi Shinohara, professor (Dermatology) and the Internal Medicine Residency staff - will talk about their work.

Led by guest moderators, the Gender Equity Lunch Series focuses on topics related to gender equity and leadership development. This series is open to all members of all genders in the Department of Medicine. Via Zoom<https://washington.zoom.us/j/92388076032>. Please register<https://forms.office.com/r/U5czH5CPeW> for this series.



________________________________

Amy Fields, Editor
amyf at uw.edu<mailto:amyf at uw.edu>


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