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<p class="MsoNormal" align="right" style="text-align:right"><a name="_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><img width="209" height="51" style="width:2.177in;height:.5312in" id="Picture_x0020_40" src="cid:image001.jpg@01DC39F9.F6800FE0"></span></a><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></span></p>

<p class="MsoNormal" align="right" style="text-align:right"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">DOM Week<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">October 10, 2025<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">News, information, and events of interest from the Department of Medicine<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none"><o:p> </o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">(if you have items for DOM Week, please email

</span></span><a href="mailto:amyf@uw.edu"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">amyf@uw.edu</span></span><span style="mso-bookmark:_Hlk199516542"></span></a><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">)

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Awards<o:p></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">ACP Laureate Award<o:p></o:p></span></b></span></p>

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</v:shapetype><v:shape id="Picture_x0020_10" o:spid="_x0000_s1034" type="#_x0000_t75" alt="Gail Pokorney" style='position:absolute;margin-left:0;margin-top:0;width:47.05pt;height:50.4pt;z-index:251666432;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

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</v:shape><![endif]--><![if !vml]><img width="63" height="67" style="width:.6562in;height:.6979in" src="cid:image025.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="Gail Pokorney" v:shapes="Picture_x0020_10"><![endif]><span style="mso-bookmark:_Hlk199516542"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.

Gail Pokorney, clinical associate professor and program director, Alaska IM Residency, is the 2025 recipient of the Laureate Award from the American College of Physicians Alaska Chapter.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The Laureate Award honors those Fellows or Masters of the College who have demonstrated by their example and conduct an abiding commitment

 to excellence in medical care, education, or research, and in service to their community, their Chapter, and the American College of Physicians.<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">DEIB news<o:p></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">UW rheumatologists join Blackfeet Nation Arthritis Conference<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_5" o:spid="_x0000_s1033" type="#_x0000_t75" alt="Grant Hughes, Jim Jarvis" style='position:absolute;margin-left:0;margin-top:0;width:73.05pt;height:50.4pt;z-index:251662336;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

<v:imagedata src="cid:image004.jpg@01DC39F9.F6800FE0" o:title="Grant Hughes, Jim Jarvis" />

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</v:shape><![endif]--><![if !vml]><img width="97" height="67" style="width:1.0104in;height:.6979in" src="cid:image026.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="Grant Hughes, Jim Jarvis" v:shapes="Picture_x0020_5"><![endif]><span style="mso-bookmark:_Hlk199516542"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Drs.

<b>Grant Hughes</b>, associate professor, and <b>Jim Jarvis</b>, professor (Rheumatology) were among community and academic participants at the Blackfeet Nation’s first Arthritis and Rheumatic Diseases Conference, discussing the impact of rheumatic diseases

 in Indigenous communities. <o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Indigenous communities have some of the highest prevalence rates of rheumatoid arthritis (RA) in North America. For example, RA is

 up to five times more common in the Blackfeet Nation compared to the general US population.<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The Blackfeet Indian Reservation sits just east of Glacier National Park and is home to the 17,321-member Blackfeet Nation, one of

 the 10 largest Indigenous Nations in the United States. Blackfeet Community College (BCC) is located on the Blackfeet Reservation and is a part of a network of tribal colleges across the western states.<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">BCC and partner organizations initiated the conference to address the challenges of arthritis, systemic lupus erythematosus, and other

 rheumatic diseases in Indigenous communities.<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Learn more on our

</span></span><a href="https://bit.ly/4h6HIte"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">news site</span></span><span style="mso-bookmark:_Hlk199516542"></span></a><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">.<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Faculty news<o:p></o:p></span></u></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_3" o:spid="_x0000_s1032" type="#_x0000_t75" alt="Radhika Narla" style='position:absolute;margin-left:0;margin-top:8.15pt;width:46.9pt;height:50.4pt;z-index:251663360;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

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</v:shape><![endif]--><![if !vml]><img width="63" height="67" style="width:.6562in;height:.6979in" src="cid:image027.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="Radhika Narla" v:shapes="Picture_x0020_3"><![endif]><span style="mso-bookmark:_Hlk199516542"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.

<b>Radhika Narla</b>, associate professor (Metabolism, Endocrinology and Nutrition) has been appointed to serve a one-year term as a member of the American College of Physicians Medical Knowledge Self-Assessment Program (ACP MKSAP) Core Committee for Endocrinology

 and Metabolism. ACP MKSAP is a comprehensive learning management system for general internal medicine physicians and internal medicine subspecialists.<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Staff news<o:p></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Staff spotlight: Rachel MacDonald<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="_x0000_s1031" type="#_x0000_t75" alt="A person and a dog posing for a selfie

AI-generated content may be incorrect." style='position:absolute;margin-left:0;margin-top:0;width:45.5pt;height:50.4pt;z-index:251667456;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

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</v:shape><![endif]--><![if !vml]><img width="61" height="67" style="width:.6354in;height:.6979in" src="cid:image028.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="A person and a dog posing for a selfie

AI-generated content may be incorrect." v:shapes="_x0000_s1031"><![endif]><span style="mso-bookmark:_Hlk199516542"></span><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Our

latest staff spotlight is on Rachel MacDonald, human resources manager in the Division of Cardiology.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Learn more about her on our

<a href="https://bit.ly/4na7xKo"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">news site<span style="mso-bookmark:_Hlk199516542"></a><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Clinical news<o:p></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Harborview’s Downtown Programs hosts pop up clinic in Hoa Mai Park<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_6" o:spid="_x0000_s1030" type="#_x0000_t75" alt="Seattle Fire Department truck in background and group of fire department employees and Harborview Downtown program employees standing in front." style='position:absolute;margin-left:0;margin-top:5.1pt;width:157.6pt;height:100.8pt;z-index:251665408;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

<v:imagedata src="cid:image010.jpg@01DC39F9.F6800FE0" o:title="Seattle Fire Department truck in background and group of fire department employees and Harborview Downtown program employees standing in front" />

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</v:shape><![endif]--><![if !vml]><img width="210" height="134" style="width:2.1875in;height:1.3958in" src="cid:image029.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="Seattle Fire Department truck in background and group of fire department employees and Harborview Downtown program employees standing in front." v:shapes="Picture_x0020_6"><![endif]><span style="mso-bookmark:_Hlk199516542"></span><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">In

 partnership with the Seattle Fire Department (SFD) and partner agencies, Harborview’s Downtown Programs hosted a four-day pop up clinic at Hoa Mai Park in Seattle’s Little Saigon neighborhood on September 9-12, 2025.<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Downtown Programs encompass the network of clinical services available through UW Medicine in downtown Seattle, including the Pioneer

 Square Clinic, Hobson Place Clinic, and Third Avenue Center. Downtown Programs clinics routinely treat patients from the neighboring community as well as people experiencing homelessness in the area.

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">“Being able start someone on life-saving medication like buprenorphine without the need for an initial period of withdrawal is particularly

 important for people experiencing homelessness,” said Dr. <b>Jared Klein</b>, associate professor (General Internal Medicine) and medical director of Downtown Programs and the Pioneer Square Clinic.<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Read the full story on our

</span></span><a href="https://bit.ly/4oc3rCg"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">news site</span></span><span style="mso-bookmark:_Hlk199516542"></span></a><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">.<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Research news<o:p></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Advancing cell therapies for diabetes<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="_x0000_s1029" type="#_x0000_t75" alt="Vincenzo Cirulli" style='position:absolute;margin-left:0;margin-top:.3pt;width:43.6pt;height:50.4pt;z-index:251664384;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

<v:imagedata src="cid:image012.jpg@01DC39F9.F6800FE0" o:title="Vincenzo Cirulli" croptop="3125f" cropbottom="15544f" cropleft="4686f" />

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</v:shape><![endif]--><![if !vml]><img width="58" height="67" style="width:.6041in;height:.6979in" src="cid:image030.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="Vincenzo Cirulli" v:shapes="_x0000_s1029"><![endif]><span style="mso-bookmark:_Hlk199516542"></span><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The

 National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has awarded an $8.6 million RC2 grant to a multidisciplinary team of researchers at the Institute for Stem Cell and Regenerative Medicine (ISCRM) led by Dr.

Vincenzo Cirulli, associate professor (Metabolism, Endocrinology and Nutrition) in collaboration with Drs. Hannele Ruohola-Baker, Laura Crisa, Shiri Levy, Julie Mathieu, and Karol Bomsztyk.

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">This transformative award will launch an ambitious interdisciplinary program to overcome one of the biggest challenges in stem cell–based

 therapies for diabetes: achieving the reliable and reproducible generation of fully functional pancreatic islets from multiple stem cell lines.<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Funding will support an effort to address the critical shortage of donor tissue for diabetes cell replacement therapies by generating

 fully functional pancreatic islets from multiple stem cell lines. Current protocols for deriving functional islet tissue remain relatively inefficient when applied to different stem cell lines, often yielding heterogeneous mixtures of mature and immature cells.

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Read more on the

<a href="https://bit.ly/430oi3c"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">ISCRM website<span style="mso-bookmark:_Hlk199516542"></a><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">.

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Polycystic Kidney Disease In Vitro Center

<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_2" o:spid="_x0000_s1028" type="#_x0000_t75" alt="Benjamin Freedman" style='position:absolute;margin-left:1.25pt;margin-top:.45pt;width:42.9pt;height:50.4pt;z-index:251660288;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

<v:imagedata src="cid:image014.jpg@01DC39F9.F6800FE0" o:title="Benjamin Freedman" cropbottom="21203f" cropleft="7864f" cropright="12780f" />

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</v:shape><![endif]--><![if !vml]><img width="57" height="67" style="width:.5937in;height:.6979in" src="cid:image031.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="Benjamin Freedman" v:shapes="Picture_x0020_2"><![endif]><span style="mso-bookmark:_Hlk199516542"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Dr.

<b>Benjamin Freedman</b>, associate professor (Nephrology) is PI on a grant to establish a Core Center dedicated to the development of polycystic kidney disease organoids and related in-a-dish technologies. Researchers have discovered that human mini-kidney

 structures grown in a petri dish can exhibit symptoms of polycystic kidney disease (‘PKD in a dish’), but currently this technology is difficult for many investigators to access and differs in certain respects from PKD in a living person.<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Establishing a core center dedicated to the development of PKD organoids and related in-a-dish technologies will greatly enable the

 community to use the technology to make research breakthroughs in our understanding of how PKD actually works and how it might be treated in a curative fashion.

<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">The center will be the first of its kind on the West Coast in 30 years of NIH programmatic funding.<o:p></o:p></span></span></p>

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</span></b></span></div>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Safeway to feature Cancer Vaccine Institute in check stand fundraiser<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_4" o:spid="_x0000_s1027" type="#_x0000_t75" alt="Nora Disis" style='position:absolute;margin-left:0;margin-top:.35pt;width:39.2pt;height:50.4pt;z-index:251661312;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

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</v:shape><![endif]--><![if !vml]><img width="52" height="67" style="width:.5416in;height:.6979in" src="cid:image032.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="Nora Disis" v:shapes="Picture_x0020_4"><![endif]><span style="mso-bookmark:_Hlk199516542"></span><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Throughout

 the month of October, Safeway and Albertsons throughout Washington, Northern Idaho and Alaska will highlight the

</span></span><a href="https://www.uwcvi.org/"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Cancer Vaccine Institute</span></span><span style="mso-bookmark:_Hlk199516542"></span></a><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">

 (CVI) at UW Medicine in their check stand fundraiser. All proceeds from this check stand campaign will benefit CVI’s breakthrough research. <o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Led by Dr.

<b>Mary (Nora) Disis</b>, professor (Hematology and Oncology), CVI is the largest academic research group dedicated to the development of cancer vaccines and has seen promising results in human clinical trials using vaccines to treat and prevent cancer and

 its recurrence.<o:p></o:p></span></span></p>

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<div class="MsoNormal" align="center" style="text-align:center"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Testing for hereditary cancers can be a lifesaver<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_1" o:spid="_x0000_s1026" type="#_x0000_t75" alt="Heather Cheng" style='position:absolute;margin-left:0;margin-top:.3pt;width:44.15pt;height:50.4pt;z-index:251659264;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

<v:imagedata src="cid:image018.jpg@01DC39F9.F6800FE0" o:title="Heather Cheng" cropright="43796f" />

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</v:shape><![endif]--><![if !vml]><img width="59" height="67" style="width:.6145in;height:.6979in" src="cid:image033.jpg@01DC39FB.B1FF10D0" align="left" hspace="12" alt="Heather Cheng" v:shapes="Picture_x0020_1"><![endif]><span style="mso-bookmark:_Hlk199516542"></span><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Research

 shows germline genetic testing — testing for a cancer risk gene you may have inherited — can save lives. Not just the patient’s, but their family members, as well. But not everyone realizes they have cancer in the family and those who do know of their family’s

 cancer history may not want to know if they themselves carry a risk for the disease.<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">“If we can identify patients with inherited cancer risk variants through genetic testing, they’ll have more treatment options,” said Dr.

<b>Heather Cheng</b>, professor (Hematology and Oncology), recently named Fred Hutch’s Clinical Director of Cancer Genetics.<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">Read the full story from

<a href="https://bit.ly/4pNQfF7"><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Hutch News<span style="mso-bookmark:_Hlk199516542"></a><span style="mso-bookmark:_Hlk199516542"><span style="font-family:"Arial",sans-serif;mso-ligatures:none">.

<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk199516542"><b><u><span style="font-family:"Arial",sans-serif;color:#39275B;mso-ligatures:none">Recent publications<o:p></o:p></span></u></b></span></p>