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<p class="MsoNormal" align="right" style="text-align:right"><a name="_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><img width="209" height="51" style="width:2.177in;height:.5312in" id="Picture_x0020_40" src="cid:image018.jpg@01DA3A6D.26C482F0"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><a name="_Hlk22564813"></a><a name="_Hlk40361261"></a><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> <o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p> </o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p> </o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">DOM Week

<br>

December 29, 2023</span></b></span><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">News, information, and events of interest from the

</span></b></span><span style="mso-bookmark:_Hlk35011064"></span><a href="http://bit.ly/1TemKEY"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Department of Medicine

</span></b></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">(If you have items for DOM week, please email

</span></span><span style="mso-bookmark:_Hlk35011064"></span><a href="mailto:amyf@uw.edu"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">amyf@uw.edu</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">)<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">2023 year in review<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Most viewed Department of Medicine News stories<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">We are sharing our top 10 most viewed stories of 2023 from our

</span></span><span style="mso-bookmark:_Hlk35011064"></span><a href="https://bit.ly/3VBmiIa"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">News Site</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">:

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<ol style="margin-top:0in" start="1" type="1">

<li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/curtis/in-memoriam"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">In

 memoriam: Jared Randall Curtis</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/alaska-im-residency-program"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Alaska

 IM Residency Program</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/2023-top-doctors"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">2023

 Top Doctors</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/hurvitz"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Sara

 Hurvitz to lead newly united Division of Hematology and Oncology</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/2023-top-docs/seattlemet"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Seattle

 Met’s Top Doctors, Physician Assistants and Nurses</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/mehra/division-head/pulmonary"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Reena

 Mehra new head of the Division of Pulmonary, Critical Care and Sleep Medicine</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/unbiased-patient-provider-interactions"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">UnBIASED

 patient-provider interactions</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/neme/medical-director-uwmc"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Santiago

 Neme new UWMC Medical Director</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/40-Under-40-Andrew-Stergachis"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">40

 under 40: Andrew Stergachis</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l0 level1 lfo1"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://mednews.uw.edu/news/center-for-indigenous-health"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">New

 Center for Indigenous Health to address American Indian and Alaska Native health inequities</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p></o:p></span></span></li></ol>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Most viewed Hutch News stories<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Department of Medicine faculty were featured in 3 of the top 5 most-read articles from Hutch news in 2023:<br>

<br>

<o:p></o:p></span></span></p>

<ol style="margin-top:0in" start="1" type="1">

<li class="MsoNormal" style="mso-list:l1 level1 lfo2"><span style="mso-bookmark:_Hlk35011064"><a href="https://www.fredhutch.org/en/news/center-news/2023/06/dr-sara-hurvitz-joins-fred-hutch-university-of-washington.html"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Dr.

 Sara Hurvitz joins Fred Hutch, University of Washington</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">

<o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l1 level1 lfo2"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://www.fredhutch.org/en/news/center-news/2023/04/viruses-linger-with-lasting-impact-hpv-hsv-hiv-long-covid.html"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Going

 long: Viruses linger with lasting impact</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> (Drs. Rachel Bender Ignacio, Jim Boonyaratanakornkit,

 Steven Pergam)<o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l1 level1 lfo2"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://www.fredhutch.org/en/news/center-news/2023/02/new-research-insights-into-cancer-tumor-necrotic-core-.html"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Dead

 to me? Insights into a tumor’s necrotic core</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> (Dr. Kevin Cheung)<o:p></o:p></span></span></li></ol>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Popular Huddle stories of 2023<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">We are featured in 3 of the top 10 stories from The Huddle in 2023:<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></b></span></p>

<ol style="margin-top:0in" start="1" type="1">

<li class="MsoNormal" style="mso-list:l2 level1 lfo3"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://huddle.uwmedicine.org/get-to-know-chief-residents-and-fellows/"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Get

 to know our Chief Residents and Fellows</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> (Omeed Alipour)<o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l2 level1 lfo3"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://huddle.uwmedicine.org/virtual-bedside-concerts-program/"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Volunteer-Led

 Virtual Bedside Concert Program Thrives</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> (Matthew Smith)<o:p></o:p></span></span></li><li class="MsoNormal" style="mso-list:l2 level1 lfo3"><span style="mso-bookmark:_Hlk35011064"></span><a href="https://huddle.uwmedicine.org/celebrate-black-womens-hair/"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Celebrating

 (But Not Touching) Black Women’s Hair</span></span><span style="mso-bookmark:_Hlk35011064"></span></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"> (Bessie Young)<o:p></o:p></span></span></li></ol>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><a name="_Hlk145003586"></a><a name="_Hlk145003443"><span style="mso-bookmark:_Hlk145003586"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></span></a></span></p>

<span style="mso-bookmark:_Hlk145003586"></span><span style="mso-bookmark:_Hlk145003443"></span>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Staff news<o:p></o:p></span></u></b></span></p>

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</v:shape><![endif]--><![if !vml]><img width="56" height="67" style="width:.5833in;height:.6979in" src="cid:image019.jpg@01DA3A6D.26C482F0" align="left" hspace="12" v:shapes="Picture_x0020_2"><![endif]><span style="mso-bookmark:_Hlk35011064"></span><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Staff

 Spotlight: Michael Dudley<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Our latest staff spotlight is on Michael Dudley, a program operations analyst in the Department of Medicine.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Learn more about him on our

<span style="mso-bookmark:_Hlk35011064"><a href="https://bit.ly/3TGomS3"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">news site<span style="mso-bookmark:_Hlk35011064"></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Clinical news<o:p></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Cord blood transplant saved woman from rare cancer<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_9" o:spid="_x0000_s1028" type="#_x0000_t75" style='position:absolute;margin-left:0;margin-top:.6pt;width:74.75pt;height:50.4pt;z-index:251662336;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:left;mso-position-horizontal-relative:margin;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

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</v:shape><![endif]--><![if !vml]><img width="100" height="67" style="width:1.0416in;height:.6979in" src="cid:image020.jpg@01DA3A6D.26C482F0" align="left" hspace="12" v:shapes="Picture_x0020_9"><![endif]><span style="mso-bookmark:_Hlk35011064"></span><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">When

 patient Alexes Harris was diagnosed with a rare blood cancer known as myelodysplastic syndromes, or MDS, and the disease reemerged after aggressive chemotherapy initially pushed the cancer into remission, her team explored a bone marrow transplant.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">For Harris, whose father was Black and Filipino, and her mother, who was white, finding a match was a challenge. "We are so underrepresented

 on the bone-marrow registry. Being African American, Asian American, Native American, Latinx — and then if you have any intersections of those identities, we have a very low likelihood of finding matches, something like 20 to 30%," she said.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">One clinician on her team, Dr.

<b>Filippo Milano</b>, associate professor (Hematology and Oncology) suggested an alternative: a transplant using stem cells obtained from umbilical cord blood. He was running a trial involving cord blood transplantation at the Fred Hutchinson Cancer Center,

 and the results had so far shown “very similar to a 100% match,” Harris recalled. The transplant was deemed a success.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Read the full story from

<span style="mso-bookmark:_Hlk35011064"><a href="https://bit.ly/3NP2Y9h"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">UW Medicine Newsroom<span style="mso-bookmark:_Hlk35011064"></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B"><o:p><span style="text-decoration:none"> </span></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Research news<o:p></o:p></span></u></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Brain scans suggest subtypes of Alzheimer’s disease<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_3" o:spid="_x0000_s1027" type="#_x0000_t75" style='position:absolute;margin-left:0;margin-top:.3pt;width:38.45pt;height:50.4pt;z-index:251661312;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:absolute;mso-position-horizontal-relative:text;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

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</v:shape><![endif]--><![if !vml]><img width="51" height="67" style="width:.5312in;height:.6979in" src="cid:image021.jpg@01DA3A6D.26C482F0" align="left" hspace="12" v:shapes="Picture_x0020_3"><![endif]><span style="mso-bookmark:_Hlk35011064"></span><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Brain

 scans have shown marked anatomical differences among the brains of patients with different subtypes of Alzheimer’s disease, researchers from the United States and Europe

<span style="mso-bookmark:_Hlk35011064"><a href="https://bit.ly/3RW9Fsy"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">reported recently<span style="mso-bookmark:_Hlk35011064"></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">The new evidence supports the theory that there are multiple, biologically distinct subgroups of the disease. If this is correct, it suggests

 that different disease factors could be driving the different subtypes, and that distinct treatments targeting those factors could improve individuals’ care.<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">“Breast cancer was once considered one disease,” said lead author Dr.

<b>Paul Crane</b>, professor (General Internal Medicine). “But we now know there are different subtypes of breast cancer that respond to different treatments. Our findings suggest a similar approach may apply to Alzheimer’s.”<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Read the full story from

<span style="mso-bookmark:_Hlk35011064"><a href="https://bit.ly/3RY8Pvk"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">UW Medicine Newsroom<span style="mso-bookmark:_Hlk35011064"></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">.

<o:p></o:p></span></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></span></p>

<div class="MsoNormal" align="center" style="text-align:center"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">

<hr size="1" width="100%" noshade="" style="color:#39275B" align="center">

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif"><o:p> </o:p></span></b></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Knowing your risk for inherited cancers matters<o:p></o:p></span></b></span></p>

<p class="MsoNormal"><!--[if gte vml 1]><v:shape id="Picture_x0020_1" o:spid="_x0000_s1026" type="#_x0000_t75" style='position:absolute;margin-left:0;margin-top:16.05pt;width:88.8pt;height:57.6pt;z-index:251659264;visibility:visible;mso-wrap-style:square;mso-width-percent:0;mso-height-percent:0;mso-wrap-distance-left:9pt;mso-wrap-distance-top:0;mso-wrap-distance-right:9pt;mso-wrap-distance-bottom:0;mso-position-horizontal:left;mso-position-horizontal-relative:margin;mso-position-vertical:absolute;mso-position-vertical-relative:text;mso-width-percent:0;mso-height-percent:0;mso-width-relative:page;mso-height-relative:page'>

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</v:shape><![endif]--><![if !vml]><img width="118" height="77" style="width:1.2291in;height:.802in" src="cid:image022.jpg@01DA3A6D.26C482F0" align="left" hspace="12" v:shapes="Picture_x0020_1"><![endif]><span style="mso-bookmark:_Hlk35011064"></span><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Around

 5-10% of cancers are germline or hereditary; commonly inherited cancers include prostate, breast, ovarian, gastrointestinal, colorectal, pancreatic and melanoma. Hereditary testing may provide options for early screenings and management of cancer at an earlier

 stage when it is more likely to be cured. DOM cancer genetic experts Drs. <b>Heather Cheng</b>, associate professor (Hematology and Oncology) and

Marianne Dubard-Gault, assistant professor (Medical Genetics) study inherited cancer risk and help patients weigh their options and interpret test results.

</span></span><span style="mso-bookmark:_Hlk35011064"><o:p></o:p></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><i><span style="font-size:12.0pt;font-family:"Arial",sans-serif">New research in 2024<o:p></o:p></span></i></span></p>

<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Cheng will continue to expand her work within prostate cancer in the new year, particularly with men who have advanced prostate cancer,

 through the Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness (PROMISE) program, where she is principal investigator.</span></span><span style="mso-bookmark:_Hlk35011064">

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Dubard-Gault is seeing artificial intelligence, or AI, beginning to be incorporated into her research, most recently on an initiative

 related to the accessibility of genetic testing educational materials. She also is particularly excited about AI’s data-processing potential, which will ultimately result in more patients being identified faster and treated more optimally. Moving into the

 new year, she said her goal is to continue to build on the work that has been done to reduce health care disparities so all patients who need hereditary testing will have access to it.<o:p></o:p></span></span></p>

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">Read the full story from

<span style="mso-bookmark:_Hlk35011064"><a href="https://bit.ly/3RK5rTQ"><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Hutch News<span style="mso-bookmark:_Hlk35011064"></a><span style="mso-bookmark:_Hlk35011064"><span style="font-size:12.0pt;font-family:"Arial",sans-serif">.

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<p class="MsoNormal"><span style="mso-bookmark:_Hlk35011064"><b><u><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#39275B">Recent publications<o:p></o:p></span></u></b></span></p>