From domweek at u.washington.edu Fri Dec 5 16:02:47 2025 From: domweek at u.washington.edu (Department of Medicine weekly newsletter via domweek) Date: Fri Dec 5 16:03:00 2025 Subject: [domweek] DOM Week, December 8-12, 2025 Message-ID: DOM Week December 5, 2025 News, information, and events of interest from the Department of Medicine (if you have items for DOM Week, please email amyf@uw.edu) DEIB news Building community through deep listening [Hands forming a circle]Our work in DOM is guided not only by our mission, but by the culture and community that bring that mission to life. Listening circles are a unique practice that aims to strengthen our collective sense of community and ensure that every member of the department feels valued, supported, and heard. Rooted in Indigenous tradition, listening circles are intentional spaces for fostering connection and community. Research shows that restorative practices like listening circles enhance social-emotional skills, build empathy and reduce conflict in schools and workplaces. Listening circles have been practiced in several areas of the department to share knowledge, promote connection and foster community (If you are interested in joining a listening circle, a DOM community building circle is coming up on Dec. 11). Learn more on our news site. Faculty news Mentor training program [A purple sign with white text that says "Mentor Training Program"]Registration is now open for the Department of Medicine longitudinal mentor training program. This interactive, multi-session mentor training course is designed to develop skills essential to mentoring and has been specifically designed to apply to research mentorship and mentoring in the clinical and educational arenas in academic medicine. It meets all of the new education requirements from the NIH. The course meets once a month from Jan. 23-June 26, 2026. Learn more about this course and register on our website. Education news Fellowship match Please join us in congratulating this year?s residents, current chief residents, former graduates, and our divisions on another successful fellowship match! Current Residents ? Seattle Danielle Tran, Endo, UW Beth Basow, Addiction Med, UW Ashley Widmer, Neph, UW Eileen Brady, Geriatric Med, Swedish Devon Zander, ID, UW Yaacoub Chahine, Card, Johns Hopkins Carrie Zografos, Card, Virginia Mason August Chen, Hem/Onc, UW Austin Chen, Pulm, UW Current Residents - Boise Thomas Enright, Hem/Onc, Univ of WI Mary Geist, Addiction Med, UW Galen Gao, Hem/Onc, UCLA Tanner McGuire, Geriatric Med, Univ of Utah Fillan Grady, Endo, UW Mike Vo, Pulmonary, Univ of MN Benjamin Hung, Geriatric Med, UCLA Ishani Joshi, Cardiology, WA Univ Alumni Varsha Karanam, Card, UT Houston Seifu Abera (?23), Interventional Card, UW Jessica Lambert, Geriatric Med, Swedish Aya Albittar ('23), Hem/Onc, UT Houston Joanna Liao, Geriatric Med, Rush Univ Read Caulkins ('21), Card, Wake Forest Angela Mang, Addiction Med, UW Joey Chiang ('24), Card, UW Megan Maurano, Neph, UCSF Celia Haering ('23), Pulm, UW Deepthi Nacharaju, Pulm, Stanford Amanda Kusztos ('25), Pulm, UW Nicole Nakamatsu, Card, UW Calvin Le ('25), Hem/Onc, Univ of Utah Sadhana Puri, Endo, Mass Gen Michael Meno ('24), Card, Univ of Hawaii Pakdee Rojanasopondist, GI, UW Wendi Norris ('01), Palliative Med, UW Hannah Steinberg, Pulm, UW Dan Olivieri ('25), Hem/Onc, Univ of Chicago Ariana Stuart, GI, UW Rebecca Resnick ('24), Card, Virginia Mason Vicki Tang, GI, OHSU Xavier Sendaydiego ('25), Card, Northwestern Hao To, Hem/Onc, UC Davis Clinical news Doctor for a Day [Doctor for a Day logo]Doctor for a Day (DFAD)?is a monthly themed academy that exposes K-12 youth to careers in healthcare. Sponsored by the Office of Healthcare Equity?s Center for Workforce Inclusion and Healthcare System Equity (WIHSE), DFAD is run primarily by UW School of Medicine students. Events are staffed in partnership with UWSOM faculty and volunteers from local school districts and non-profits. Thus far, DFAD has reached over 3,000 students and serves over 560 students per academic year.? DOM faculty and fellows joined DFAD volunteers for November?s event, ?Diabetes Sweet Truths: Protecting Sight, Filters, and Balance? at Issaquah High School. DOM volunteers were coordinated by Dr. Lorena Alarcon-Casas Wright, professor of clinical practice (Metabolism, Endocrinology, and Nutrition), and Drs. Bessie Young, professor, and Justin Bullock, assistant professor (Nephrology). Learn more on our news site. Research news For many blood cancer patients, CAR T-cell therapy is game-changing [Mazyar Shadman]CAR T-cell therapy, which transforms patients? own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. Expert consensus is that CAR T should be considered as a potent tool in the treatment toolbox if more conventional first-line treatments have not eradicated a patient?s disease. In the latest episode of ?From Bench to Bedside and Beyond,? Dr. Mazyar Shadman, professor (Hematology and Oncology) explains why CAR T-cell therapy should be considered for patients who relapse, discusses the barriers to accessing CAR T-cell therapy, and what patients and providers should know about this treatment. ________________________________ Phase 1/2 Clinical Trial of EN-374 for Treatment of X-CGD [Hans-Peter Kiem and Andre Lieber]Ensoma, an in vivo cellular engineering company with a mission to advance the future of medicine through one-time therapies, has dosed the first patient in the company?s Phase 1/2 clinical trial of EN-374. EN-374 is an in vivo hematopoietic stem cell (HSC)-directed gene insertion therapy for the treatment of X-linked chronic granulomatous disease (X-CGD), a rare and severe genetic disorder. It is designed as a one-time treatment to restore immune function in patients who currently face a lifelong burden of severe infections, repeated hospitalizations and limited therapeutic options. Drs. Hans-Peter Kiem, professor (Hematology and Oncology) and Andr? Lieber, professor (Medical Genetics) founded Ensoma, and the in vivo HSC gene therapy technology came from Dr. Lieber?s lab. Read the Ensoma press release for more information. ________________________________ [OnCore logo: A blue circle with black text on white background: OnCore.]Introduction to OnCore Clinical Trials Management System Starting January 1, 2026, the UW Diversity in Clinical Trials (DCT) policy will be implemented to improve the completeness and quality of enrollment data for clinical trial participants. To meet reporting requirements, research teams will be responsible for entering enrollment data into OnCore Clinical Trials Management System (CTMS), a web-based resource utilized by UW and Fred Hutch to manage clinical trials with reporting and billing compliance needs. CTMS is offering a webinar for research teams new to OnCore CTMS on Dec. 11, 12-1pm, to provide a brief overview of the DCT Policy and scope, the use of OnCore for DCT data collection, how to submit new studies, and how to access and navigate OnCore. Please register for this webinar. Recent publications Dr. Christina Baik, associate professor (Hematology and Oncology) is co-author of ?Amivantamab Plus Lazertinib in Atypical EGFR-Mutated Advanced Non-Small Cell Lung Cancer: Results From CHRYSALIS-2? in the Journal of Clinical Oncology. Dr. Petter Bjornstad, professor (Metabolism, Endocrinology and Nutrition) is senior author of ?Unmasking the hidden burden of prediabetes on kidney function? in Kidney International. Dr. Crystal Brown, assistant professor (Pulmonary, Critical Care and Sleep Medicine) is co-author of ?A Research Agenda to Mitigate Racial and Ethnic Disparities in U.S. Critical Care Medicine: An Official American Thoracic Society Research Statement? in the American Journal of Respiratory and Critical Care Medicine. Dr. Heather Cheng, professor (Hematology and Oncology) is co-author of ?Magnetic Resonance Imaging or Confirmatory Biopsy for Patients With Prostate Cancer Receiving Active Surveillance? in JAMA Oncology. Dr. Jason Dominitz, professor (Gastroenterology) is lead author of ?Association Between Adenoma Detection Rate and Prevalent Colorectal Cancer Detection Rate in a National Colonoscopy Registry? in Gastroenterology. DOM co-authors are Rachel Issaka and Cynthia Ko. Dr. Christopher Goss, professor (Pulmonary, Critical Care and Sleep Medicine) is co-author of ?Maximising opportunity for therapeutic success: sequential participation in cystic fibrosis nucleic acid-based therapy trials? in The Lancet Respiratory Medicine. Dr. William Grady, professor (Gastroenterology) is co-author of ?Gastric (Foveolar)-Type Dysplasia in Barrett's Esophagus: A Clinical, Molecular, and Long-Term Outcome Study? in the American Journal of Gastroenterology. Dr. Hans-Peter Kiem, professor (Hematology and Oncology) is co-author of ?Pooled CAR-T screening in pig-tailed macaques identifies designs with enhanced proliferation, trafficking, and persistence? in Blood. Dr. Barbara Lam, assistant professor (Hematology and Oncology) is co-author of ?Validation of a Risk Score for Cancer-Associated Thrombosis Using Nationwide EHR Data? in JAMA Network Open. Dr. Scott Lee, professor (Gastroenterology) is lead author of ?Long-Term Safety of Mirikizumab in Patients With Moderately to Severely Active Ulcerative Colitis: An Integrated 2-Year Safety Analysis? in the American Journal of Gastroenterology. Drs. Ryan Lynch, associate professor, and Ajay Gopal, professor (Hematology and Oncology) are co-authors of ?Remission Assessment by Circulating Tumor DNA in Large B-Cell Lymphoma? in the Journal of Clinical Oncology. Dr. Ann O?Hare, professor (Nephrology) is lead author of ?Illness Experiences of Veterans Reporting Long-Term Symptoms or Health Challenges from COVID-19: Results from the VA COVID-19 Observational Research Collaboratory? in the Journal of General Internal Medicine. DOM co-authors are Elizabeth Vig, Catherine Butler, and George Ioannou. Dr. Shailly Pandey, R3, is lead author and Dr. Matthew Triplette, associate professor (Pulmonary, Critical Care and Sleep Medicine) is senior author of ?Common Determinants of Lung Cancer Screening Uptake in Three High-Risk and Underserved Communities? in the Journal of the American College of Radiology. DOM co-authors are Kristina Crothers and Jehan Budak. Dr. Chetan Seshadri, professor (Allergy and Infectious Diseases) is co-author of ?A systematic approach to tuberculosis vaccine development? in Cell. Dr. Jennifer Specht, professor, is lead author and Dr. Hannah Linden, professor (Hematology and Oncology) is senior author of ?The Role of Estrogen Receptor?Targeted PET with 16?-18F-Fluoro-17?-Estradiol in Predicting Response to Endocrine Therapies in Metastatic Breast Cancer: A Metaanalysis? in the Journal of Nuclear Medicine. Dr. Eugene Yang, professor of clinical practice (Cardiology) is co-author of ?Evaluation of the PREVENT Equations in a Nationwide Cohort of 7.7 Million Korean Adults? in JACC. In the news Dr. Ernie Blevins, research associate professor (Metabolism, Endocrinology and Nutrition) is quoted in ?Brain scientists are seeking weight-loss drugs without the nausea? from NPR. Dr. Helen Chu, professor (Allergy and Infectious Diseases) is quoted in ?CDC Vaccine Panel in Disarray over Hepatitis B Vote? in Scientific American. Dr. Adrienne Shapiro, assistant professor (Allergy and Infectious Diseases) is quoted in ?The Benefits of HIV Research? Let Us Count the Ways? in Poz and ?Six striking findings from major TB conference? in Times Live. Events of interest DOM Community Building Circle Event The Center for Restorative Practice and the Department of Medicine are partnering to provide a special community building circle event (virtual) scheduled for Dec. 11, 3-4pm. Given the attacks on DEIB, DOJ investigations, political and sociocultural adversity, and devastating world events, CRP and DOM want to provide a supportive space for collective coping and enhancing well-being. A zoom link and more information (i.e., circle prompts) will be provided upon registration. Please RSVP for this event. ________________________________ DEIB Community Gathering All are welcome to attend an in-person Diversity, Equity, Inclusion and Belonging (DEIB) community gathering event on Dec. 11, 5:00-7:00pm at M?tier Brewing Co. Please RSVP for this event Weekly Calendar, December 8-12, 2025 Our events calendar is posted on our website. Coming up Women Faculty Leadership Workshop: Building Effective Teams The Women in Medicine & Science (WIMS) Committee invites you to join the next session of the 2025-2026 Women Faculty Leadership Series on Building Effective Teams. These workshops are open to all, they aim to foster career development, well-being, and leadership skills among women faculty in the School of Medicine. Dec. 16, 4-5pm. Please register. ________________________________ Medicine Grand Rounds Upcoming 2025 Grand Rounds: Dr. Reena Mehra, professor and head (Pulmonary, Critical Care and Sleep Medicine) will present ?Reflections on a Journey of Purpose, Persistence, and Possibility in Academic Medicine? on Dec. 19. ________________________________ Amy Fields, Editor amyf@uw.edu [Bluesky logo][Facebook logo - blue circle with with lowercase f][Instagram logo/camera image][LinkedIn logo/blue background with lowercase letters "in"][You Tube logo / a white play button on red background] To subscribe/unsubscribe from this list, go to: https://mailman1.u.washington.edu/mailman/listinfo/domweek -------------- next part -------------- An HTML attachment was scrubbed... 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Name: image017.png Type: image/png Size: 3421 bytes Desc: image017.png URL: From domweek at u.washington.edu Fri Dec 12 15:58:30 2025 From: domweek at u.washington.edu (Department of Medicine weekly newsletter via domweek) Date: Fri Dec 12 15:58:39 2025 Subject: [domweek] DOM Week, December 15-19, 2025 Message-ID: DOM Week December 12, 2025 News, information, and events of interest from the Department of Medicine (if you have items for DOM Week, please email amyf@uw.edu) Awards Nora Disis honored as Seahawks' Delta Community Captain [Nora Disis with Seattle Seahawks mascot]Dr. Mary (Nora) Disis, professor (Hematology and Oncology) has received the Delta Community Captain award for her groundbreaking work developing cancer vaccines that harness the body's immune system to fight disease. The Seattle Seahawks and Delta team members were also able to visit UW Medicine to see her groundbreaking research firsthand and learn how it's shaping the future of care for our patients. Learn more on the Seahawks website. Staff news [Kelli Corning]Staff Spotlight: Kelli Corning Our latest staff spotlight is on Kelli Corning, associate director of the Seattle Internal Medicine Residency Program. Learn more about her on our news site. Faculty news You Matter: Voices in Health Care podcast [Anita Chopra]Dr. Anita Chopra, clinical associate professor (General Internal Medicine) is co-hosting You Matter: Voices in Healthcare, a podcast produced by the Power of Providers at the Washington State Department of Health (DOH). The show features conversations with health care workers and leaders about resilience, managing stress, preventing burnout, and the systemic changes needed to better support Washington's health care workforce. Episode 1 is available now and new episodes will air every month. ________________________________ Larry Corey makes 'leaders and best' list [Larry Corey]Dr. Lawrence Corey, professor (Allergy and Infectious Diseases) was highlighted in the latest issue of Medicine at Michigan. The feature honors 175 alumni and faculty who have helped establish the University of Michigan Medical School's reputation as the "leaders and best" in celebration of its 175th anniversary. Dr. Corey appears at #83 on the list. ________________________________ Kay Johnson to be featured in the ACGME Clinician-Educator Journal Club [Kay Johnson]Dr. Kay Johnson, professor (General Internal Medicine) and Stuart Slavin, Vice President of Well-Being for the ACGME, will lead a discussion based on the paper they co-authored with Dr. Traci Takahashi, associate professor, (General Internal Medicine), "Excellent vs Excessive: Helping Trainees Balance Performance and Perfectionism." The monthly ACGME Clinician Educator Journal Club brings together current and aspiring clinician educators, authors, and ACGME staff to explore timely topics and recent journal articles in medical education. Dec. 18, 10am. Please register for this event. Clinical news Practitioner Leads in Quality & Safety In recognition of their substantial contributions to local healthcare quality and safety, Drs. Jeffrey Edelman, professor (Pulmonary, Critical Care and Sleep Medicine), Justina Gamache, clinical assistant professor (Pulmonary, Critical Care and Sleep Medicine), Yoshio Hall, professor (Nephrology), Julie He, clinical assistant professor (Cardiology), Lauren Lin, chief resident, Ann O'Hare, professor (Nephrology), Clinton Olivas, chief resident, Mala Sanchez, clinical assistant professor (General Internal Medicine), Vicki Tang, chief resident, and Molly Tokaz, assistant professor (Hematology and Oncology) have been awarded the title of Practitioner Lead in Quality & Safety (PLQS) within the Hospital & Specialty Medicine service line at the VA Puget Sound Health Care System. PLQS titles are based on contributions made over the previous year to achieving safer, higher quality care for our Veterans. [Images of the ten Practitioner leads in quality & safety] Research news Breast Cancer Research Foundation grants Scientists with the Fred Hutch Cancer Center/University of Washington/Seattle Children's Cancer Consortium received another year of funding from the Breast Cancer Research Foundation (BCRF) to pursue research into new therapies, new biomarkers and new vaccines meant to improve outcomes in this deadly disease. [Nancy Davidson, Nora Disis, Mary-Claire King, Hannah Linden.]Dr. Nancy Davidson, professor (Hematology and Oncology) received funding to continue investigation of the NRF2 pathway and how it shapes the breast tumor microenvironment, with an eye toward exploiting it to overcome immune checkpoint inhibitor resistance. Dr. Mary (Nora) Disis, professor (Hematology and Oncology) received funding to determine the optimal doses for the single-antigen vaccines and combining multiple antigens into a single DNA construct for improved immune response and further investigate vaccine-induced changes to the metabolic function of fat tissue and immune cells and test the safety of the vaccine. Dr. Mary-Claire King, professor (Medical Genetics) received funding to further development of a new technology platform that enables researchers to sequence large swaths of DNA in single very long strands, rather than thousands of short bits. King is also exploring dysregulation of gene expression as a basis for inherited breast cancer. Dr. Hannah Linden, professor (Hematology and Oncology) will continue investigating whether a PET/CT progesterone tracer known as FFNP can better predict response to endocrine therapy coupled with the CDK4/6 inhibitor abemaciclib (Verzenio). Read the full story from Hutch News. ________________________________ [Mengyang Di]Lymphoma Research Foundation Career Development Award Dr. Mengyang Di, assistant professor (Hematology and Oncology) has been awarded a 2026 Lymphoma Research Foundation Clinical Investigator Career Development Award for her proposal entitled "PROMOTE-FL: Pirtobrutinib-Mosunetuzumab Enhancing Efficacy in Previously Treated Follicular Lymphoma." ________________________________ Call for applications: Cystic Fibrosis research The UW NIDDK P30 Cystic Fibrosis Research Translation Center (CFRTC) is seeking applications for Pilot and Feasibility Studies focused on development and/or translation of promising laboratory findings that may lead to novel therapies for individuals with cystic fibrosis (CF). First stage applications are due Feb. 1, 2026. Learn more on the CFRTC website. Recent publications Dr. Sarah Baker, acting assistant professor (Allergy and Infectious Diseases) is lead author of "An outer membrane vesicle vaccine prevents lung pathology in a macaque model of pneumonic melioidosis" in Nature Communications. Drs. Joseph Delaney, research associate professor (General Internal Medicine) and Stephanie Ruderman, research scientist, and Heidi Crane, professor (Allergy and Infectious Diseases) are co-authors of "Age modifies the association between sex and the plasma inflammatory proteome in treated HIV" in the Journal of Clinical Investigation. Drs. Diana Eng, research scientist, and Stuart Shankland, professor (Nephrology) are co-authors of "Renal PIEZO2 is an essential regulator of renin" in Cell. Dr. Nicole Ehrhardt, assistant professor (Metabolism, Endocrinology and Nutrition) is co-author of "Preparing to Meet the Needs of a Growing Older Adult Population with Type 1 Diabetes: A Narrative Review" in the Journal of General Internal Medicine. Dr. Michelle Erickson, research associate professor (Gerontology and Geriatric Medicine) is senior author of "Transport of CCL2 across an induced pluripotent stem cell-derived in vitro model of the human blood-brain barrier is heparan sulfate-dependent" in PLOS One. DOM co-authors are William Banks and May Reed. Dr. Helen Jack, assistant professor (General Internal Medicine) is senior author of "HIV Prevention for People Releasing from Incarceration: A Qualitative Pre-implementation Study" in the Journal of General Internal Medicine. DOM co-author is Susan Graham. Dr. Erin Kross, professor (Pulmonary, Critical Care and Sleep Medicine) is co-author of "Society of Critical Care Medicine Clinical Practice Guidelines on Adult End-of-Life Care in the ICU" in Critical Care Medicine. Dr. Ryan Lynch, associate professor, is lead author and Dr. Ajay Gopal, professor (Hematology and Oncology) is senior author of "Pharma steps back from Hodgkin lymphoma: now what?" in Blood Advances. Dr. Yue-Harn Ng, clinical professor (Nephrology) is senior author of "Association between Area Deprivation Index, Kidney Transplant Waitlisting, and Reasons for Denial" in the Clinical Journal of the American Society of Nephrology. DOM co-authors are David Prince and Bessie Young. Dr. Tahsin ?zpolat, fellow, is lead author and Dr. Moritz Stolla, associate professor (Hematology and Oncology) is senior author of "Transfusion-Induced Functional and Metabolic Shifts in Stored Platelets: Limitations of In Vitro Assessment" in Blood VTH. Dr. Mayuree Rao, acting assistant professor (General Internal Medicine) is co-author of "Associations Between Social Risks and Obesity in High-risk Veterans" in the Journal of General Internal Medicine. Dr. Mazyar Shadman, professor (Hematology and Oncology) is lead author of "Real-world treatment patterns and clinical outcomes among patients with diffuse large B-cell lymphoma in a US healthcare claims database" in Blood Cancer Journal and senior author of "The Evolving Therapeutic Landscape of Richter Transformation" in Current Hematologic Malignancy Reports. Dr. Asa Tapley, clinical assistant professor (General Internal Medicine) is co-author of "Determining vaccine responders in the presence of baseline immunity using single-cell assays and paired control samples" in Biostatistics. Dr. Suzanne Watnick, professor (Nephrology) is co-author of "Core Interventions for the Prevention of Peritoneal Dialysis Related Infections" in the Clinical Journal of the American Society of Nephrology. Dr. Eugene Yang, professor of clinical practice (Cardiology) is co-author of "Cuffless Devices for the Measurement of Blood Pressure: A Scientific Statement From the American Heart Association" in Hypertension. In the news Dr. Nicole Chow Ahrenholz, clinical associate professor (General Internal Medicine) is quoted in "What Shots and Vaccines Do I Need to Get to Travel Right Now?" in Fodor's Travel. Dr. John Amory, professor (General Internal Medicine) is quoted in "Don't Push Through the Winter Blues: 4 Tips to Help" in Right as Rain. Dr. Oscar Bailon, clinical assistant professor (Cardiology) is quoted in "Keep your heart content as holidays approach" from UW Medicine Newsroom. Dr. Debra Cherry, associate professor (General Internal Medicine) is quoted in "New EPA-Approved Pesticides Stir Controversy" in Everyday Health. Dr. Helen Chu, professor (Allergy and Infectious Diseases) is quoted in "West Coast alliance continues to back universal hepatitis B vaccine" in the Seattle Times. Dr. Barak Gaster, professor (General Internal Medicine) is quoted in "Alzheimer Disease Blood Test Cleared for Primary Care, but Questions Remain About Its Use" in JAMA Medical News. Dr. Scott Hagan, associate professor (General Internal Medicine) talked to KUOW in "Ask a Doctor: Ozempic, Wegovy and GLP-1 drugs in general." Dr. Lorena Alarcon-Casas Wright, professor of clinical practice (Metabolism, Endocrinology and Nutrition) is quoted in "What happens to your blood sugar when you eat sourdough bread regularly?" from MSN. Dr. Eugene Yang, professor of clinical practice (Cardiology) is quoted in "How Wi-Fi Could Become an Invisible, No-Touch ECG" from Medscape. Events of interest Medicine Grand Rounds Dr. Reena Mehra, professor and head (Pulmonary, Critical Care and Sleep Medicine) will present "Reflections on a Journey of Purpose, Persistence, and Possibility in Academic Medicine" at Medicine Grand Rounds on Dec. 19, 12-1pm, Turner Conference room and via zoom. Weekly Calendar, December 15-19, 2025 Our events calendar is posted on our website. Coming up Upcoming Grand Rounds Dr. Dorrie Rhoads (Univ. of Oklahoma) will present "Building Academic-Tribal Partnerships to Advance Implementation Research and Improve Cancer Outcomes" at Medicine Grand Rounds on Jan. 16, 12-1pm, Turner Conference room and via zoom. ________________________________ Amy Fields, Editor amyf@uw.edu [Bluesky logo][Facebook logo - blue circle with with lowercase f][Instagram logo/camera image][LinkedIn logo/blue background with lowercase letters "in"][You Tube logo / a white play button on red background] To subscribe/unsubscribe from this list, go to: https://mailman1.u.washington.edu/mailman/listinfo/domweek -------------- next part -------------- An HTML attachment was scrubbed... URL: -------------- next part -------------- A non-text attachment was scrubbed... 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Name: image019.png Type: image/png Size: 1852 bytes Desc: image019.png URL: -------------- next part -------------- A non-text attachment was scrubbed... Name: image020.png Type: image/png Size: 3421 bytes Desc: image020.png URL: From domweek at u.washington.edu Fri Dec 19 16:51:27 2025 From: domweek at u.washington.edu (Department of Medicine weekly newsletter via domweek) Date: Fri Dec 19 16:51:38 2025 Subject: [domweek] DOM Week, December 22-26, 2025 Message-ID: DOM Week December 19, 2025 News, information, and events of interest from the Department of Medicine (if you have items for DOM Week, please email amyf@uw.edu) Awards Call for Nominations: John R. Pettit Endowed Leadership Award Nominations are now being accepted for the annual John R. Pettit Endowed Leadership Award, which honors the long and varied service of its namesake. All nominations must be made by or before noon on Jan. 31. The award will be given out in the spring. The Pettit Award is open to professional staff members who are currently employed by UW Medicine. Preferred recipients will have five or more years of service at UW Medicine. Education news Spotlight on resident research: Pranusha Atuluru Colorectal cancer is a major cause of cancer deaths in the U.S. and worldwide and many patients undergo surgery for treatment. [Pranusha Atuluru] In the latest resident scholarship spotlight, ?Identifying Barriers to Surveillance Care among Colorectal Cancer Survivors,? Dr. Pranusha Atuluru?s research focuses on barriers to colorectal cancer patients receiving follow up care who have undergone surgery. The most commonly reported barriers were fears surrounding colonoscopy results and cancer recurrence, as well as challenges with bowel preparation. On the other hand, the strongest facilitators included patients? motivation to seek reassurance and the support they received from the clinic in scheduling their appointments. Dr. Atuluru?s interest in colorectal cancer is driven by its disproportionate impact on people from lower socioeconomic backgrounds and minority communities, as well as the potential for early detection that completely changes the course of a patient?s life. View the spotlight on the residency website. Faculty news [Doug Paauw]Douglas Paauw makes ?leaders and best? list Dr. Douglas Paauw, professor (General Internal Medicine) was highlighted in the latest issue of Medicine at Michigan. The feature honors 175 alumni and faculty who have helped establish the University of Michigan Medical School?s reputation as the ?leaders and best? in celebration of its 175th anniversary. Clinical news CARES Awards [Yellow heart on a purple background with an image of an award in the middle of the yellow heart/UW Medicine Cares Award logo]The UW Medicine Cares Award, established in 2013, recognizes and celebrates the accomplishments of individuals and teams who consistently exemplify UW Medicine?Service Culture Guidelines. Congratulations to the following DOM members who received Fall 2025 Cares Awards: Individual: Carolyn Houk, clinical associate professor (General Internal Medicine) Teams: Addiction Medicine Consult Team: DOM members are Elly Bhatraju, assistant professor, Jocelyn James, associate professor, Jared Klein, associate professor, Sarah Leyde, assistant professor, and Joseph Merrill, professor (General Internal Medicine) Community Heart Failure Program: DOM members are Danee Hidano, acting assistant professor, and Mrinal Yadava, assistant professor (Cardiology) UWMC Critical Care Advanced Practice Providers: DOM members are Pulmonary, Critical Care and Sleep Medicine Teaching Associates: Giana DeNisi, Jessica Kwon-Enriquez, Katherine McCusker, Michaela Morris, Jacob Okleshen, Courtney Pullen, Gayle Roberson-Wiley, Lori Schwark, Matthew Smith, Jessica Stasi, Sue Stewart, Melissa Winckler, Cameron Wright, Sarah Welch, and Ruby Young Research news Drug turns lung cells into slow-release antibiotic depots [Shawn Skerrett and Eoin West]A new designer drug that turns lung immune cells into slow-release antibiotic dispensers can clear a lethal pneumonia infection in mice, researchers report. In the study, researchers created a compound known as a prodrug, an inactive form of a drug that becomes active only after being metabolized by the body. Prodrugs can be engineered to extend drug half-life, to ease storage and delivery ? and to target specific cells or tissues. The team?s goal was to create a prodrug that slowly released an antibiotic inside immune cells called alveolar macrophages. Macrophages are large cells that engulf and digest bacteria throughout the body. Alveolar macrophages are found in the lung?s tiny air sacs, the alveoli. In earlier research, the researchers had used a similar design to kill bacteria that hide inside macrophages ? a survival strategy that lets pathogens evade immune attack and many antibiotics. The new study tested whether the same approach could also kill bacteria in the surrounding lung tissue, said Dr. Shawn Skerrett, professor (Pulmonary, Critical Care and Sleep Medicine). ?We had seen that the antibiotic stays within cells for an extended period of time, suggesting the macrophages might serve as a reservoir from which the antibiotic would leak out into the surrounding tissue,? Skerrett said. The researcher team also included DOM faculty member Dr. T. Eoin West, professor (Pulmonary, Critical Care and Sleep Medicine). Read the full story from UW Medicine Newsroom. ________________________________ Latest in breast cancer research Several DOM faculty presented their research at the latest San Antonio Breast Cancer Symposium, the largest breast cancer research meeting in the world. ?Naked chemo? vs. ?smart chemo? [Sara Hurvitz]Dr. Sara Hurvitz, professor and head (Hematology and Oncology) spoke on a new class of cancer drugs known as antibody drug conjugates, or ADCs, in a session on translational controversies. These new combinations ? a monoclonal antibody that binds to a specific protein expressed on tumor cells, a cancer-killing chemotherapy drug and a ?linker? that connects them and triggers the drug?s release in the cell ? have changed treatment for many patients with breast cancers. ctDNA for early prediction of ER+/HER2- mets [Heather Parsons]Dr. Heather Parsons, associate professor (Hematology and Oncology) presented data on a cohort of patients within the large international PALLAS trial, which tested the benefit of two years of CDK4/6 inhibitor palbociclib (Ibrance) plus endocrine therapy versus endocrine therapy alone in early-stage ER+, HER2- breast cancers after surgery and treatment. A better way to ?measure the unmeasurable? [Jennifer Specht] Dr. Jennifer Specht, professor (Hematology and Oncology) presented findings from the ECOG-ACRIN Cancer Research Group?s FEATURE trial (1183), which used modified FDG-PET/CT scan criteria to predict whether or not patients with metastatic ER+/HER2- breast cancer that?s spread to the bone are responding to treatment or not. Read the full story from Hutch News. Recent publications Dr. Ryan Cassaday, professor (Hematology and Oncology) wrote ?Challenges and opportunities for improvement in the practical management of adults with acute lymphoblastic leukemia? in Blood Advances. Dr. Denise Chac, staff scientist, is lead author and Dr. Ana Weil, assistant professor (Allergy and Infectious Diseases) is senior author of ?Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens? in Nature Communications. DOM co-author is Susan Markiewicz. Dr. Petros Grivas, professor (Hematology and Oncology) is co-author of ?Advanced Urologic Cancer Consensus Conference (AUC3) 2025: Expert consensus on the management of renal cell and urinary tract cancers? in CA: A Cancer Journal for Clinicians. Dr. Steven Kahn, professor (Metabolism, Endocrinology and Nutrition) is co-author of ?Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes? in the New England Journal of Medicine. Dr. Meghan Kiefer, associate professor (General Internal Medicine) is lead author of ?Improving USMLE Step 1 outcomes in academically vulnerable students through a targeted, competency-based curriculum? in BMC Medical Education. Dr. Linnaea Schuttner, assistant professor (General Internal Medicine) is lead author of ?Patient-Centered Prioritization of Health Care Processes for Multimorbidity? in JAMA Network Open. DOM co-authors are Scott Hagan and Katherine Ritchey. Dr. Mazyar Shadman, professor (Hematology and Oncology) is co-author of ?Epcoritamab monotherapy for Richter transformation (EPCORE CLL-1): findings from a single-arm, multicentre, open-label, phase 1b/2 trial? in The Lancet Haematology. Dr. Philip Vutien, assistant professor (Gastroenterology) is co-author of ?Long-term effectiveness of tenofovir alafenamide versus entecavir in treatment-na?ve chronic hepatitis B: A REAL-B study? in the American Journal of Gastroenterology. In the news Dr. Nisha Bansal, professor (Nephrology) is quoted in ?Heart and Kidney Diseases and Type 2 Diabetes May Be One Ailment? in Scientific American. Dr. Philip Mease, clinical professor (Rheumatology) is quoted in ?Beneath the Surface: Who should prescribe GLP-1s?? in Healio. Dr. Reena Mehra, professor and head (Pulmonary, Critical Care and Sleep Medicine) participated in a Q&A with Healio to discuss ?Guideline recommendations established for managing OSA in inpatient setting.? Events of interest Quiet week, December 22-26 As we continue to rebuild resilience and focus on mental health, we would like to preserve department-wide quiet weeks throughout the year. During these weeks, we hope that individuals can limit non-essential meetings to recharge and reflect, as well as thoughtfully minimize emails. We realize that this will not be possible for everyone but encourage all to take breaks when they are able. Weekly Calendar, December 22-26, 2025 Our events calendar is posted on our website. Coming up Upcoming Grand Rounds Dr. Dorrie Rhoads (Univ. of Oklahoma) will present ?Building Academic-Tribal Partnerships to Advance Implementation Research and Improve Cancer Outcomes? at Medicine Grand Rounds on Jan. 16, 12-1pm, Turner Conference room and via zoom . ________________________________ Amy Fields, Editor amyf@uw.edu [Bluesky logo][Facebook logo - blue circle with with lowercase f][Instagram logo/camera image][LinkedIn logo/blue background with lowercase letters "in"][You Tube logo / a white play button on red background] To subscribe/unsubscribe from this list, go to: https://mailman1.u.washington.edu/mailman/listinfo/domweek -------------- next part -------------- An HTML attachment was scrubbed... URL: -------------- next part -------------- A non-text attachment was scrubbed... Name: image003.png Type: image/png Size: 101235 bytes Desc: image003.png URL: -------------- next part -------------- A non-text attachment was scrubbed... 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Name: image026.jpg Type: image/jpeg Size: 1879 bytes Desc: image026.jpg URL: From domweek at u.washington.edu Fri Dec 26 15:24:50 2025 From: domweek at u.washington.edu (Department of Medicine weekly newsletter via domweek) Date: Fri Dec 26 15:25:01 2025 Subject: [domweek] DOM Week, December 29, 2025 - January 2, 2026 Message-ID: DOM Week December 26, 2025 News, information, and events of interest from the Department of Medicine (if you have items for DOM Week, please email amyf@uw.edu) Awards Julie Gralow named one of the 100 most influential people in oncology in 2025 [Julie Gralow]Dr. Julie Gralow, professor emeritus (Hematology and Oncology) has been named on the 100 most influential people in oncology in 2025. The list recognizes the changemakers in cancer care who have helped shape current practice in oncology and continue to drive innovation and research towards better outcomes, advocacy, philanthropy, leadership and education. Gralow is an internationally recognized leader in breast cancer clinical trials, survivorship, and global oncology. DEIB News Nominate colleagues for Black History Month feature [Black history month graphic]Throughout the year, the UW Medicine Cultural Observances Implementation Subcommittee partners with Vitals to celebrate cultural observances. This includes feature articles in which employees share their perspectives and experiences. Please help them identify employees to be featured in the February 2026 article by submitting nominations. Employees may also self-nominate. Only nominate employees who have shared their cultural identity with you, and please make it clear that their participation is voluntary. To nominate a colleague, email their name, role and email address (with their permission) by Jan. 9 to Vitals. Faculty news [Dace Trence]Dace Trence elected President of the American Association of Endocrinology Dr. Dace Trence, professor emeritus (Metabolism, Endocrinology, and Nutrition) has been elected President of the American Association of Endocrinology (AACE). Founded in 1991, AACE is a global, inclusive community of more than 5,700 endocrine-focused clinical members, affiliates and partners. Dr. Trence was also the plenary speaker at the Consortium for Medical Research and Education (CMRE) 2025 conference in New Delhi, India. Research news Building resilience into care of chronic heart conditions [picture of Drs. Babak Nazer, Eric Krieger, Jill Steiner and psychologist Tracy Herring]Just a few months old and supported by a philanthropic donation, UW Medicine's Cardiac Resilience program aims to address psychosocial symptoms among two patient groups: those with arrhythmias who have received ICD shocks or CPR, and those with a congenital structural defect that necessitates heart surgeries from childhood through adulthood. "We're starting with heart patients who we think bear a disproportionate burden of mental health symptoms," said Dr. Babak Nazer, professor (Cardiology) and heart-rhythm specialist. He cofounded the program with psychologist Tracy Herring and congenital heart disease doctors Eric Krieger and Jill Steiner. "There's a shortage of mental health care access across the country, so we were fortunate to find a psychologist who could join the Heart Institute." Read the full story from UW Medicine Newsroom. Recent publications Dr. Rachel Bender Ignacio, associate professor (Allergy and Infectious Diseases) is lead author of "Why Americans are Dying Younger? NIH Is Not the Problem. Our Broken Healthcare Delivery Is" in the Journal of Infectious Diseases. Dr. Paul Cornia, professor, is lead author, and Dr. Tyler Albert, associate professor (General Internal Medicine) is senior author of "Career choices of ambulatory chief residents: A 20-year, multicenter study" in the American Journal of Medicine. DOM co-author is Elizabeth Schackmann. Dr. George Ioannou, professor (Gastroenterology) is lead author of "Effectiveness of the 2024-2025 KP.2 COVID-19 vaccines in the United States during long-term follow-up" in Nature Communications. DOM co-author is Edward Boyko. Dr. Judith Tsui, professor (General Internal Medicine) is co-author of "Retreatment of Hepatitis C Virus Among People Who Inject Drugs" in Clinical Infectious Diseases. In the news Dr. Nazem Akoum, professor (Cardiology) is quoted in "Can wearable devices help prevent heart disease?" from MSN. Dr. Helen Chu, professor (Allergy and Infectious Diseases) is quoted in "Flu season is ramping up, and some experts are 'pretty worried'" from CBS News. Weekly Calendar, December 29, 2025 - January 2, 2026 Our events calendar is posted on our website. Coming up Opportunity to provide feedback for the UW strategic plan The UW is working on a strategic plan to guide us through 2030. They are offering a listening session specifically for the Health Science units, to include your hopes, aspirations, and ideas for this plan. Jan. 6, 3-4:30pm, South Campus Center 316 and via zoom. Please RSVP to reserve your spot (a zoom link will be provided after registration). Upcoming Grand Rounds Dr. Dorrie Rhoads (Univ. of Oklahoma) will present "Building Academic-Tribal Partnerships to Advance Implementation Research and Improve Cancer Outcomes" at Medicine Grand Rounds on Jan. 16, 12-1pm, Turner Conference room and via zoom ________________________________ Amy Fields, Editor amyf@uw.edu [Bluesky logo][Facebook logo - blue circle with with lowercase f][Instagram logo/camera image][LinkedIn logo/blue background with lowercase letters "in"][You Tube logo / a white play button on red background] To subscribe/unsubscribe from this list, go to: https://mailman1.u.washington.edu/mailman/listinfo/domweek -------------- next part -------------- An HTML attachment was scrubbed... URL: -------------- next part -------------- A non-text attachment was scrubbed... Name: image001.jpg Type: image/jpeg Size: 10322 bytes Desc: image001.jpg URL: -------------- next part -------------- A non-text attachment was scrubbed... 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