[domweek] DOM Week, March 11-15, 2024

[Department of Medicine weekly newsletter]

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DOM Week
March 8, 2024
News, information, and events of interest from the Department of Medicine <http://bit.ly/1TemKEY>

(If you have items for DOM week, please email amyf at uw.edu<mailto:amyf at uw.edu>)


Awards
[cid:image003.jpg at 01DA7171.D471C580]Dr. Connie Celum, professor (Allergy and Infectious Diseases) is the 2024 recipient of the Research Excellence Award from the Association of Schools and Programs of Public Health (ASPPH). ASPPH awards honor individuals who exhibit excellence in education, research, practice, student services, and exceptional community engagement.

Learn more from the SPH website<https://bit.ly/48JrVum>.

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[cid:image005.jpg at 01DA7171.D471C580]Dr. Mengru "Ruru" Wang, clinical assistant professor (Gerontology and Geriatric Medicine) has been selected by UW School of Medicine students as the 2024 UW nominee for the Arnold P. Gold Humanism in Medicine Award.

This is a national teaching award presented by the AAMC Organization of Student Representatives (OSR) to one clinical faculty member from medical schools across the country who exemplifies positive mentoring, student collaboration, and teaching compassionate, patient-centered care.


Faculty news
In memoriam: Dr. David Dichek
[cid:image007.jpg at 01DA7171.D471C580]Dr. David Dichek, professor (Cardiology) passed away unexpectedly on March 2. He was 69. Dichek graduated Phi Beta Kappa with a bachelor's degree in Romance languages and literatures from Princeton University and received his medical degree from the University of California, Los Angeles. He was an internal medicine resident at Massachusetts General Hospital and a clinical fellow in cardiology at Johns Hopkins Hospital in Baltimore.

He served as head of the Cardiovascular Gene Therapy Unit at the National Heart, Lung, and Blood Institute before joining the faculty at the University of California, San Francisco in 1994. In 2001, he joined the University of Washington as a professor, associate director of research in the Division of Cardiology and the John L. Locke, Jr. Family Endowed Chair in Cardiovascular Research and Treatment. He also held an adjunct appointment in the Department of Lab Medicine and Pathology.

Dichek had a clinical practice in general cardiology and an internationally known research program that focused on gene therapy for cardiovascular disease and molecular mechanisms of aortic aneurysm formation and atherosclerotic plaque rupture.

He recently expressed his thoughts on running a research lab, writing manuscripts, and life outside of work in a post for the Arteriosclerosis, Thrombosis, and Vascular Biology blog, ATVB_net<https://bit.ly/3wyWt4D>.

"David has been an integral part of our Cardiology Division for decades, always with a clear eye towards quality research and clinical care," said Interim Cardiology Division Head Dr. Jordan Prutkin. "He touched all our lives, and I extend my deep condolences to his family and those who knew him best."

Details about a memorial service will follow.

Learn more about him on the cardiology website<https://bit.ly/49LAu9q>.

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In memoriam: Jerry Palmer
[cid:image009.jpg at 01DA7171.D471C580]Dr. Jerry Palmer, professor emeritus (Metabolism, Endocrinology and Nutrition) passed away on Feb. 28. He was 80. Palmer received his medical degree from the Upstate Medical Center in Syracuse, NY, completed residency at Dartmouth and an endocrinology fellowship at the University of Washington. Recruited by founding Department of Medicine Chair Dr. Robert Williams, Palmer remained at the UW for 45 years until his retirement and appointment to emeritus professor in 2019. He served as chief of endocrinology at the Seattle VA for nearly 30 years.

His many significant accomplishments included creating the Diabetes Care Center<https://mednews.uw.edu/news/diabetes-clinic> at UW (and directing the center for 12 years), contributing to the largest study that proved that controlling blood sugar helps prevent complications from diabetes, and the discovery of insulin autoantibodies, which garnered him a nomination by international colleagues for a Nobel Prize in Medicine.

Services will be held at St. Luke's Lutheran Church in Federal Way on Saturday, March 9 at 10am. Reception to follow.

Learn more about him on our news site<https://bit.ly/3uQqE7b>.


Research news
Colorectal cancer incidence increases in people under 50
[cid:image011.jpg at 01DA7171.D471C580]In the last 30 years, the incidence of colorectal cancer has gone up by 50% among people under 50, and by 2030, the disease is projected to top the list of U.S. cancer deaths in this demographic. "We really need to have people understand that colorectal cancer isn't an old people's disease anymore," said Dr. Rachel Issaka, associate professor (Gastroenterology) and director of the Fred Hutch/UW Medicine Population Health Colorectal Cancer Screening Program<https://www.fredhutch.org/en/research/institutes-networks-ircs/population-health-colorectal-cancer-screening-program.html>.

Issaka's comments follow the January release of the American Cancer Society's Cancer statistical report for 2024<https://acsjournals.onlinelibrary.wiley.com/doi/full/10.3322/caac.21820>. Among people under 50 in the U.S., the report said, colorectal cancer is currently the No. 1 cause of cancer death among men and the No. 2 cause of death among women. The report stated that, while colorectal cancer continues to decline among people over 60, it is following a decades-long upward trajectory among those 50 and younger.

Read the full story from UW Medicine Newsroom<https://bit.ly/3V5qpzv>.

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Trial seeks people with long COVID cognitive symptoms
[cid:image013.jpg at 01DA7171.D471C580]The UW will conduct the first two clinical trials to study long COVID for the National Institutes of Health. The clinical trials are part of the NIH RECOVER (Researching Covid to Enhance Recovery) Initiative. The Seattle site is currently enrolling potential participants for RECOVER-NEURO, a trial that will examine interventions for brain fog, memory lapses, difficulty with attention and other cognitive problems that persistently trouble some people who have had COVID. Dr. Helen Chu, professor (Allergy and Infectious Diseases) will lead the research team.

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Prototype device effectively treated multiorgan failure
[cid:image015.jpg at 01DA7171.D471C580]Clinical trial results published last week<https://bit.ly/3IsHV9x> describe a novel medical device that, in a 10-patient pilot, showed remarkable success at rescuing people from multiorgan failure caused by acute-on-chronic liver failure.

All 10 patients had been officially listed for liver transplant but were delisted when their clinical condition deteriorated considerably amid multiorgan failure. They all underwent treatment on the new device and became healthy enough to discontinue supportive measures and be relisted for transplant.

Dr. Suhail Ahmad, professor emeritus (Nephrology) is co-lead developer of the device and lead author on the paper. DOM co-authors are Drs. Iris Liou, clinical associate professor, Robert Carithers, professor emeritus, and Renuka Bhattacharya, clinical professor (Gastroenterology).

Read the full story from UW Medicine Newsroom<https://bit.ly/48FxolT>.

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The advanced HIV disease research landscape
[cid:image017.jpg at 01DA7171.D471C580]Dr. Adrienne Shapiro, assistant professor (Allergy and Infectious Diseases) was part of a consultancy convened by the World Health Organization (WHO) to outline the research landscape for advanced HIV disease (AHD) and contributed to a report on AHD<https://bit.ly/3TjuNcW>, which was recently published by the WHO and circulated to global stakeholders.

Learn more on our news site<https://bit.ly/3PclHMD>.


Recent publications
Dr. Nisha Bansal, professor (Nephrology) is lead author of "Cardiovascular-Kidney-Metabolic Health Syndrome: What Does the American Heart Association Framework Mean for Nephrology?<https://bit.ly/48FEtmE>" in the Journal of the American Society of Nephrology.

Drs. Pavan Bhatraju, associate professor (Pulmonary, Critical Care and Sleep Medicine), Bruce Psaty, professor (General Internal Medicine), and Bryan Kestenbaum, professor (Nephrology) are co-authors of "Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury<https://go.nature.com/3P7BDA0>" in Nature Medicine.

Dr. Connie Celum, professor (Allergy and Infectious Diseases) is senior author of "HIV Preexposure Prophylaxis With Emtricitabine and Tenofovir Disoproxil Fumarate Among Cisgender Women<https://bit.ly/49JAo1V>" in JAMA.

Drs. Paul Cornia, professor, and Meghna Shah, clinical assistant professor (General Internal Medicine) are co-authors of "Contemporary Management and Outcomes of Veterans Hospitalized With Alcohol Withdrawal: A Multicenter Retrospective Cohort Study<https://bit.ly/3PcVaz3>" in the Journal of Addiction Medicine.

Dr. Lee Cranmer, professor (Hematology and Oncology) is co-author of "Phase II Trial of nab- Sirolimus in Patients With Advanced Malignant Perivascular Epithelioid Cell Tumors (AMPECT): Long-Term Efficacy and Safety Update<https://bit.ly/4a0biM8>" in the Journal of Clinical Oncology.

The family of the late Dr. J. Randall Curtis (daughter Alice and wife Amy) wrote about his last days and medical aid in dying in: "The Strength It Takes to Suffer<https://bit.ly/3T3B1wl>" in JAMA.

Dr. Jason Goldman, clinical assistant professor (Allergy and Infectious Disease) is co-author of "Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer<https://bit.ly/49FMZDz>" in Cell Reports.

Dr. Barbara Konkle, professor (Hematology and Oncology) is co-author of "Giroctocogene fitelparvovec gene therapy for severe hemophilia A: 104-week analysis of the phase 1/2 Alta study<https://bit.ly/3TaJ0HQ>" in Blood.

Dr. Christopher Longenecker, associate professor (Cardiology) is lead author of "Nurse-Led Strategy to Improve Blood Pressure and Cholesterol Level Among People With HIV: A Randomized Clinical Trial<https://bit.ly/3VokUwj>" in JAMA Network Open.

Dr. Ryan Lynch, associate professor (Hematology and Oncology) wrote "Toward a cure for cHL without chemotherapy<https://bit.ly/4alZJzd>" in Blood.

Dr. Robert Montgomery, professor (Hematology and Oncology) is co-author of "A combinatorial genetic strategy for exploring complex genotype-phenotype associations in cancer<https://go.nature.com/4a7pYsZ>" in Nature Genetics.

Dr. Ila Nimgaonkar, R2, is lead author, and Dr. Joshua Hill, associate professor (Allergy and Infectious Diseases) is senior author of "Outcomes in Hematopoietic Cell Transplant and Chimeric Antigen Receptor T Cell Therapy Recipients with Pre-Cellular Therapy SARS-CoV-2 Infection<https://bit.ly/3UYbCqu>" in Clinical Infectious Diseases. DOM co-authors are Leah Yoke, Masumi Ueda Oshima, Jordan Gauthier, Marco Mielcarek, Michael Boeckh and Catherine Liu.

Dr. Moritz Stolla, associate professor (Hematology and Oncology) is senior author of "Platelet dysfunction reversal with cold-stored vs. room temperature-stored platelet transfusions<https://bit.ly/4381IEC>" in Blood.


In the news
Dr. Amanda Casto, acting assistant professor (Allergy and Infectious Diseases) is quoted in "COVID? Again? A guide to the latest symptoms and treatment<https://bit.ly/3wTjZtc>." In the Star Tribune.

Dr. H. Nina Kim, professor (Allergy and Infectious Diseases) joined the Healthcare for Humans podcast to discuss "Hepatitis B-Culturally Responsive Care to Address the Stigma & Silence<https://bit.ly/3wFHbuW>."

Dr. Ryan Lynch, associate professor (Hematology and Oncology) is quoted in "Novel Regimens Yield High Response Rates for Older, Hodgkin Lymphoma Patients<https://bit.ly/3TqU19u>" in Medpage Today.


Events of interest
Medicine Grand Rounds
Dr. Richard Johnson, professor (University of Colorado Anschutz Medial Campus) will present "Fructose and Uric acid: The Double Whammy Driving Metabolic Diseases" at Medicine Grand Rounds<https://medicine.uw.edu/grand-rounds> on Friday, March 15, 2024,12-1pm, via zoom<https://washington.zoom.us/j/812197730>.



Weekly Calendar, March 11-15, 2024
Our events calendar is posted on our website<https://medicine.uw.edu/news/trumba-calendar>.


Coming up
Gender Equity Lunch Series: Advanced Practice Provider Career Development
Moderator: Leah Yoke, PA-C and UWMC's Chief PA
Panel:

  *   Alison Beieler, PA-C, Infectious Disease, HMC
  *   Jennifer Beckman, ARNP, Cardiology, UWMC
  *   Jeannine Sanford, ARNP, Deputy Directory of APPs, FHCC
  *   Matthew Smith, PA-C, Pulmonary, Critical Care, Sleep Medicine, UWMC

March 27, 12-1pm, via zoom<https://washington.zoom.us/j/99283251748>. Please RSVP<https://forms.office.com/r/970vZtVwd1>.



________________________________

Amy Fields, Editor
amyf at uw.edu<mailto:amyf at uw.edu>


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