[domweek] DOM Week, January 23-27, 2023

[Department of Medicine weekly newsletter]

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DOM Week
January 20, 2023
News, information, and events of interest from the Department of Medicine <http://bit.ly/1TemKEY>

(If you have items for DOM week, please email amyf at uw.edu<mailto:amyf at uw.edu>)



Awards
[cid:image003.jpg at 01D92CEE.57F93A10]Leah Yoke, teaching associate (Allergy and Infectious Diseases) is the recipient of the Debra Mattson Infectious Disease Research Award for her abstract "CMV Retinitis during Maintenance Chemotherapy for Acute Lymphoblastic Leukemia".

The Debra Mattson Infectious Disease Research Award was created in honor of Physician Assistant Debra Mattson's 30-year career in caring for thousands of patients and her role on the Fred Hutch Cancer Center Infectious Disease Consult Service. The award honors the best paper or abstract that demonstrates improvement in diagnosis, prevention, and treatment of infections in immunocompromised patients.


Faculty news
[cid:image005.jpg at 01D92CEE.57F93A10]Dr. Andrea Kalus, associate professor (Dermatology) has been appointed holder of the John E. Olerud Endowed Chair for Dermatology Training<https://derm.uw.edu/news/dr-john-e-olerud-endowed-professorship-elevated-endowed-chair>. Named after Dr. John E. Olerud, professor emeritus and former Division Head, earnings from the Olerud endowment are used to support and enrich the educational mission of the UW Dermatology residency program, including the ability to recruit and retain distinguished faculty in dermatology and to strengthen dermatology training.


Education news
[cid:image007.jpg at 01D92CEE.57F93A10]Dr. Roxanne Hicks, R3, has been accepted into the Society of General Internal Medicine (SGIM) Leadership in Health Policy Program (LEAHP). The Leadership in Health Policy Program<https://bit.ly/3CVq20v> aims to develop SGIM members who are effective and active health policy advocates and local health policy experts, leaders, and teachers; to offer health policy career development resources and opportunities to all SGIM members; and to develop an expanding, national cadre of Health Policy Committee (HPC) members and broaden engagement in the Society's health policy efforts. LEAHP is a 1-year program for a national cohort of approximately 20 participants.

"This is a fantastic opportunity for Dr. Hicks to develop leadership skills in health policy," said Program Director Ken Steinberg. "I'm so proud and excited that she was accepted into the program!"



Research news
Genetic diagnosis helps guide care of childhood hearing loss
[cid:image009.jpg at 01D92CEE.57F93A10]A recent study, reported Jan.12 in JAMA Otolaryngology-Head & Neck Surgery<https://bit.ly/3WiLZxu>, studied a group of more than 400 youngsters with bilateral sensorineural hearing loss affecting both ears.

The study was led by Ryan J. Carlson, an M.D./Ph.D. student in the Medical Scientist Training Program at the University of Washington School of Medicine. It was conducted during his training with Mary-Claire King, the senior author and professor of medicine and genome sciences at the UW School of Medicine and with Jay Rubinstein, professor of otolaryngology and head and neck surgery at the UW School of Medicine.

The findings show that genetic testing is a valuable tool in determining prognosis for a child's hearing loss and in predicting how useful a cochlear implant could be for that child's understanding of speech.

Read the full story from UW Medicine Newsroom<https://bit.ly/3ktrqkA>.

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Drs. Andre Lieber, professor (Medical Genetics) and Hans-Peter Kiem, professor [cid:image011.jpg at 01D92CEE.57F93A10] (Medical Oncology) have received an R01 from the NIAID for $5.7 million over 5 years to study "In vivo HSC gene therapy using a multi-modular HDAd vector for HIV cure." Their goal is to further develop a simple in vivo approach for durable HIV prophylaxis and therapy. Their approach requires only intravenous injections and could be provided as an outpatient treatment. They will also address current biological barriers to achieving an HIV cure.


Recent publications
Wynn Burke, research consultant, and Dr. William Grady, professor (Gastroenterology) are co-authors of "Nondestructive 3D Pathology Image Atlas of Barrett Esophagus With Open-Top Light-Sheet Microscopy<https://bit.ly/3wdpVcX>" in the Archives of Pathology & Laboratory Medicine.

Drs. Connie Celum, professor, and Jairam Lingappa, professor (Allergy and Infectious Diseases) are co-authors of "Upregulation of PTPRC and Interferon Response Pathways in HIV-1 Seroconverters Prior to Infection<https://bit.ly/3WoMdDx>" in the Journal of Infectious Diseases.

Dr. Michelle Erickson, research assistant professor (Gerontology and Geriatric Medicine) is senior author of "Transport of the Proinflammatory Chemokines C-C Motif Chemokine Ligand 2 (MCP-1) and C-C Motif Chemokine Ligand 5 (RANTES) across the Intact Mouse Blood-Brain Barrier Is Inhibited by Heparin and Eprodisate and Increased with Systemic Inflammation<https://bit.ly/3GMBhK2>" in the Journal of Pharmacology and Experimental Therapy. DOM co-authors are May Reed and William Banks.

Dr. David Garcia, professor (Hematology) is co-author of "Derivation and Validation of a Clinical Risk Assessment Model for Cancer-Associated Thrombosis in Two Unique US Health Care Systems<https://bit.ly/3ITfWkC>" in the Journal of Clinical Oncology.

Dr. A. McGarry Houghton, professor (Pulmonary, Critical Care and Sleep Medicine) is co-author of "Posttranslational modifications induce autoantibodies with risk prediction capability in patients with small cell lung cancer<https://bit.ly/3iNn5Za>" in Science Translational Medicine.

Dr. George Ioannou, professor, is lead author and Christopher Savard, research scientist (Gastroenterology) is senior author of "Genetic deletion or pharmacologic inhibition of the Nlrp3 Inflammasome did not ameliorate experimental NASH<https://bit.ly/3ZMIvGB>" in the Journal of Lipid Research. DOM co-authors are Vishal Kothari and Sum Lee.

Dr. Brian Wood, associate professor, is lead author, and Dr. Joanne Stekler, professor (Allergy and Infectious Diseases) is senior author of "Could home HIV self-testing ever become a game changer?<https://bit.ly/3kqMbgY>" in Clinical Infectious Diseases.


In the news
Dr. Jim Boonyaratanakornkit, acting assistant professor (Allergy and Infectious Diseases) is quoted in "What You Need to Know About the XBB.1.5 'Kraken' Variant<https://bit.ly/3ZJJyH7>" in Very Well Health.

Dr. Yonatan Buber, associate professor (Cardiology) is quoted in "AHA News: Simple or Moderate Congenital Heart Defects Might Not Impair Fertility<https://bit.ly/3GVfgsl>" in U.S. News & World Report.

Dr. Paul Drain, associate professor (Allergy and Infectious Diseases) is quoted in "Why Rapid COVID-19 Test Results Are Getting More Confusing<https://bit.ly/3IReKOR>" in TIME.

Research by Dr. Benjamin Freedman, associate professor (Nephrology) and colleagues is featured on the NIH Director's Blog, "Chipping Away at the Causes of Polycystic Kidney Disease<https://bit.ly/3WDqKH7>." Dr. Freedman is also quoted in "Animal testing no longer required for drug approval. But high-tech substitutes aren't ready<https://bit.ly/3ZKYjJT>." in USA Today.

Dr. Irl Hirsch, professor (Metabolism, Endocrinology and Nutrition) talked to Spokane Public Radio for "UW medical professor: Diabetes is now a public health problem<https://bit.ly/3GNRfUb>."

Dr. Paul Pottinger, professor (Allergy and Infectious Diseases) is quoted in "Too Many People Are Using Neti Pots and Vaporizers Unsafely, Survey Suggests<https://bit.ly/3GVwrdE>" in Everyday Health.

Dr. Eugene Yang, clinical professor (Cardiology) is quoted in "Apps want to be your new doctor's office. Is that a good idea?<https://wapo.st/3GPmzSt>" in the Washington Post.


Events of Interest
UW Medicine Diabetes Institute Director Candidate Seminar
[cid:image013.jpg at 01D92CEE.57F93A10]Dr. Suneil Koliwad (UCSF) will present, "A scientist's journey at the intersection of nutrition, immunity, and metabolism" on Jan. 24, 4-5pm. Dr. Koliwad is an endocrinologist who specializes in diabetes, obesity and other metabolic disorders and conditions linked to metabolism. He serves as chief of UCSF's endocrinology and metabolism division. Please register<https://diabetesmetabseminars.com/event/suneil-koliwad-md-phd/> to receive zoom link.

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Gender Equity Lunch Series: Mentoring and Trailblazing
[cid:image015.jpg at 01D92CEE.57F93A10]On Wednesday, Jan. 25, 2023, 12-1pm, the inaugural recipients of our Gender Equity Awards in Mentorship and Trailblazing - Dr. Stephanie Page, professor and head (Metabolism, Endocrinology and Nutrition), Dr. Michi Shinohara, professor (Dermatology) and the Internal Medicine Residency staff - will talk about their work. Led by guest moderators, the Gender Equity Lunch Series focuses on topics related to gender equity and leadership development. This series is open to all members of all genders in the Department of Medicine. Via Zoom<https://washington.zoom.us/j/92388076032>. Please register<https://forms.office.com/r/U5czH5CPeW> for this series.

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Save the date: Seattle Sounders March 18
[cid:image017.jpg at 01D92CEE.57F93A10]The Department of Medicine is proud to sponsor a Seattle Sounders match on Saturday, March 18, at noon at Lumen Field in downtown Seattle. We are reserving a block of seats for the event, and a link to buy discounted tickets will become available within the coming weeks where you will be able to purchase tickets for yourself and friends and family on a first come, first served basis. Food vouchers will be provided to each participating employee.



Weekly Calendar, January 23-27, 2023
Our events calendar is posted on our website<https://medicine.uw.edu/news/trumba-calendar>.


Coming up
Equity, Diversity and Inclusion Survey
On January 17, UW Medicine launched an Equity, Diversity and Inclusion Survey<https://depts.washington.edu/hcequity/edisurvey/> to identify baseline measures of Equity, Diversity, and Inclusion across UW Medicine and provide actionable data to help prioritize areas for work at the entity and departmental levels. All UW Medicine faculty, staff, and trainees are invited and encouraged to participate in the survey which will take about 10-15 minutes to complete. The survey will be open from Jan. 17 - Feb. 28, 2023. Please participate in this survey to help make us a more equitable and anti-racist institution.

Endocrinology and Diabetes Update for Primary Care
This comprehensive two-day course on endocrinology and diabetes is geared towards primary care providers. There is an immense need for education as the incidence of diabetes and endocrinology disorders in the general population, and primary care clinics carry the major burden of these patients. Didactic lectures offered in this program will provide the latest information on current topics related to diabetes, endocrinology, and guideline updates. Feb. 9-10. For more information and to register for this course, please visit the CME website<https://bit.ly/3GcklMH>.

Eli Estey symposium on the pathogenesis and therapy of AML
A scientific symposium honoring Dr. Eli Estey's many contributions to leukemia research and care will be held at the Fred Hutchinson Cancer Center on May 19, 2023 from 9am to 5:30pm with state-of-the-art talks by esteemed AML colleagues. For more information and to register, please visit the Hematology website<https://hematology.uw.edu/news/aml-pathogenesis-and-therapy-scientific-symposium-honor-dr-eli-estey>.

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Amy Fields, Editor
amyf at uw.edu<mailto:amyf at uw.edu>


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