[domweek] DOM Week, January 9-13, 2023

Department of Medicine weekly newsletter domweek at u.washington.edu
Fri Jan 6 16:10:34 PST 2023


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DOM Week
January 6, 2023
News, information, and events of interest from the Department of Medicine <http://bit.ly/1TemKEY>

(If you have items for DOM week, please email amyf at uw.edu<mailto:amyf at uw.edu>)


Celebrating 75 years

[cid:image041.png at 01D921E9.64EF9620]The Department of Medicine was founded in 1948 with an original group of six stellar faculty members teaching and practicing at a single site. We are now the largest department at the University of Washington.

To commemorate our 75th anniversary, we plan to highlight our achievements and milestones, spotlight our divisions and programs, honor our history, and outline our plans for our future.

We start by acknowledging our people. Please visit our website<https://bit.ly/3VStLnf> where we look back at 75 of the changemakers who have shaped our history and 75 of our many emerging leaders who are helping to chart the path forward.

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Call for members: DOM Strategic Plan implementation workgroups
Are you interested in participating in our strategic planning efforts? More information about our strategic plan and the workgroups, progress, etc. is available on our intranet<https://intranet.medicine.uw.edu/resources/strategic-plan>. If you would like to take part in shaping the future of the department, please indicate your interest by completing this short survey<https://bit.ly/3CsGkOe>. Thank you!


Awards
William J. Bremner Endowed Mentorship Awards
[cid:image042.jpg at 01D921E9.64EF9620]Congratulations to the 2022 William J. Bremner Endowed Mentorship Award<https://bit.ly/3Ih4Jdz> recipients, Drs. Thomas Gallagher, professor (General Internal Medicine) and associate chair for patient care quality improvement, safety and value, and Dr. W. Conrad Liles, professor (Allergy and Infectious Diseases) and associate chair for research.

Dr. Gallagher received the award for excellence in mentoring clinician/scholars and full-time clinical faculty, and Dr. Liles received the award for excellence in mentoring physician/scientists.

Recognizing that mentorship is critical to success across all phases of faculty's careers in academic medicine, these awards honor faculty members for their contributions to the scientific, educational, and patient care missions of the department through exemplary mentorship.

The endowment was created and the name changed in 2018 to commemorate and express appreciation to Dr. William Bremner for his legendary wisdom, vision, coaching and sponsorship that fostered countless trainees and faculty in pursuing their passion and in reaching their ultimate potential.

Learn more about the DOM Mentorship Program<https://bit.ly/3ICADl1>.


DEI news
Bias Navigator Program
[cid:image012.jpg at 01D920F8.881E0FB0]The department is offering a new resource - the Bias Navigator Program<https://bit.ly/3jS5u2E> - to staff, faculty and trainees. This program was piloted from August-December with DOM central staff, and the divisions of Cardiology, Nephrology and Pulmonary, Critical Care and Sleep Medicine and is now open to the entire department.

Our Navigators are trained individuals dedicated to providing safe, confidential support to help guide Department of Medicine faculty, staff and trainees through bias incidents they may have experienced in the workplace. Navigators can provide a safe space to express concerns, help to navigate through the resources and options available, and provide conflict resolution coaching. This program is not intended to replace any existing programs/tools (i.e. BIRT, academic or staff HR processes, or Peer to Peer support).

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Save the date: DOM Diversity Lecture Series
[cid:image011.png at 01D920F8.881E0FB0]The Department of Medicine, in partnership with the Institute for Common Power, is proud to present "The Impact of the Pandemic and the 'Racial Reckoning' on Health Outcomes and American Democracy" on Feb. 1, 3:30-5pm.

In this panel discussion, three of the editors/contributors (Merritt, Williams, Tsai) to the anthology, Afterlife: A Collective History of Loss and Redemption in Pandemic America will join Minnesota Community Care executive officer, Rueben Moore, and Dr. David Horne, associate chair for DEI, to discuss the impact of the Pandemic and the "Racial Reckoning" on everything from healthcare to the health of American democracy.

For more information and to register, please visit our website<https://bit.ly/3GEQaz7>.

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MLK Day rally and march
In recognition of Martin Luther King Day, the DOM Diversity Council welcomes support and participation in the MLK Day rally and march<https://bit.ly/3X6PdF8> on Jan. 16. The event will commence at Garfield High School. Additional workshops are also available earlier in the day. DOM participants will meet at the bottom of the stairs in front of the Garfield High School auditorium at 12:15pm for the march. Please contact Sean (seang151 at uw.edu<mailto:seang151 at uw.edu>) or Dave (dhorne at uw.edu<mailto:dhorne at uw.edu>) if you intend to join us.



Faculty news
Faculty spotlight: Larry Dean
[cid:image045.jpg at 01D921E9.64EF9620]The Huddle talked to Dr. Larry Dean, professor of medicine (Cardiology) and surgery, about his two different but surprisingly complementary passions - medicine and food. Dean is the founding director of the Regional Heart Center (now Heart Institute) and has been in academic medicine for over 35 years. He is also the first medical director of Clinical Products and Smart Innovation (CPSI) - chairing a multidisciplinary committee that oversees clinician and nurse-led groups that evaluate products, technologies and purchased services from vendors. In addition, he has a food blog called The Eating Places<https://bit.ly/3jUO1pX> that captures his passion for dining out.

Read more about him in The Huddle<https://bit.ly/3It3qrY>.

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[cid:image046.jpg at 01D921E9.64EF9620]Dr. James Floyd, associate professor (General Internal Medicine) has been appointed to the National Academies of Sciences, Engineering, and Medicine Review of Relevant Literature Regarding Adverse Events Associated with Vaccines<https://bit.ly/3CmquF8> committee. The committee will review literature to examine the associations between vaccines and specific adverse events.


Education news
Physician-Scientist Learning Pathway
The Internal Medicine Residency Program's Physician-Scientist Learning Pathway provides dedicated research time, mentorship, a core curriculum, and professional development activities to interested residents planning careers as physician-scientists.

Please welcome the four new members of the new Physician-Scientist Learning Pathway:

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Dr. Joshua Bloomstein hopes to apply data science methodologies to the investigation of immunological systems to better personalize care in inflammatory, infectious, and oncological diseases as well as build AI models to mitigate healthcare access inequities.


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Dr. Jacob Leary is interested in the biology of cancer stem cells and host immune cell-cancer cell interactions in the tumor microenvironment, and aims to advance the understanding of precision therapies in cancer.


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Dr. Ila Nimgaonkar is planning a research-intensive career studying the interface of virology and oncology and susceptibility to chronic and severe viral infections, particularly within immunocompromised populations.


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Dr. Noga Rogel is interested in translational research that will integrate computational models and technology development to generate new therapies, and investigating systemic diseases to better understand and characterize immunologic processes.




Research news
Study illuminates sugar's role in common kidney disease
[cid:image051.jpg at 01D921E9.64EF9620]A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

One key discovery of the study: Sugar appears to play a role in the formation of fluid-filled cysts that are PKD's hallmark. In people, these cysts grow big enough to impair kidney function and ultimately cause the organs to fail, necessitating dialysis therapy or transplant.

The findings were published Dec. 23 in Nature Communications<https://go.nature.com/3ZbQDAb>. Co-lead authors are Sienna Li and Ramila Gulieva, research scientists in the lab of Dr. Benjamin Freedman, associate professor (Nephrology). He is co-senior author with Dr. Jonathan Himmelfarb.

"Sugar uptake is something that kidneys do all the time," said Freedman. "We found that increasing the levels of sugar in the dish cultures caused cysts to swell. And when we employed drugs known to block sugar absorption in the kidneys, it blocked this swelling. But I think it relates less to blood sugar level and more to how kidney cells take in sugar - which in this process seemed to go rogue and give rise to cysts."

Read the full article from UW Medicine Newsroom<https://bit.ly/3vZPYod>.

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If broached, peritoneal dialysis might be a better option
[cid:image052.jpg at 01D921E9.64EF9620]It's an unforgettable, life-changing moment when someone learns that their kidneys are functioning so badly that dialysis or a transplant will be necessary to survive. Given the gravity, it is disconcerting that one study of the patient population showed that 100% had been told about in-center hemodialysis, but only about 30% had been told of peritoneal dialysis, the stay-at-home, do-it-yourself option.

"The wheels of our healthcare system have long been greased to get patients into that hemodialysis chair," said Dr. Rajnish Mehrotra, professor and head (Nephrology). "It is starting to change, but many people who might want to dialyze at home are not told they have that choice."

Read more from UW Medicine Newsroom<https://bit.ly/3jZ2PE2>.
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[cid:image053.jpg at 01D921E9.64EF9620]Dr. Jose Garcia, professor (Gerontology and Geriatric Medicine) will receive the Western Association of Physicians/Western Society for Clinical Investigation (WAP/WSCI) Outstanding Investigator Award and give an invited talk: "From Bench to Bedside: Developing Treatments for Cancer Cachexia" at the 2023 WAP/WSCI annual conference this month.

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[cid:image054.jpg at 01D921E9.64EF9620]Dr. Sakeneh Zraika, research associate professor (Metabolism, Endocrinology and Nutrition), has received an R01 award for $2.1M from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) for her project "Effects of Cholesterol in Pancreatic Islets". The goal is to understand why cholesterol-lowering statins increase the risk of new onset type 2 diabetes. Previously unrecognized effects of statins on cholesterol transport and metabolism in insulin-producing islet cells will be investigated in order to identify novel therapeutic targets to mitigate statin-induced islet dysfunction/death.
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The UW Medicine Diabetes Institute (UWMDI), Diabetes Research Center (DRC), and Nutrition Obesity Research Center (UW NORC) are jointly soliciting applications for Pilot and Feasibility Research Awards. Letters of Intent are due Jan.11. More information is available on their website<http://depts.washington.edu/diabetes/funding-opportunities/>.


Recent publications
Dr. Lawrence Corey, professor (Allergy and Infectious Diseases) is senior author of "Novel engineered chimeric engulfment receptors trigger T cell effector functions against SIV-infected CD4+ T cells<https://bit.ly/3WKKNUC>" in Molecular Therapy Methods & Clinical Development.

Dr. David Koelle, professor (Allergy and Infectious Diseases) is co-author of "NIAID workshop on T cell technologies<https://go.nature.com/3QgWQ9Y>" in Nature Immunology.

Dr. Hongyang Pi, fellow, is co-lead author and Drs. Peter Leary, associate professor, and Sina Gharib, professor (Pulmonary, Critical Care and Sleep Medicine) are co-senior authors of "Metabolomic Signatures Associated With Pulmonary Arterial Hypertension Outcomes<https://bit.ly/3WQSLLV>" in Circulation Research. DOM co-authors are David Ralph and Samuel Rayner.

Dr. Brook Pittenger, clinical instructor (General Internal Medicine) is co-author of "Adapting SQUIRE 2.0 to Create a Quality Improvement Evidence-Based Medicine Critical Appraisal Tool (QI-EBM-CAT) for Graduate Medical Education Trainees<https://bit.ly/3Cs2cJz>" in the Journal of Graduate Medical Education.

Dr. Coralynn Sack, assistant professor (General Internal Medicine) is senior author of "Ambient Air Pollution and Stroke: An Updated Review<http://bit.ly/3ImAzFO>" in Stroke. DOM co-author is Joel Kaufman.

Dr. Mazyar Shadman, associate professor (Medical Oncology) is lead author of "COVID-19 Vaccination Response and Its Practical Application in Patients With Chronic Lymphocytic Leukemia<https://bit.ly/3VMJ53M>" in HemaSphere. DOM co-author is Catherine Liu.

Dr. Laura Spece, acting assistant professor (Pulmonary, Critical Care and Sleep Medicine) is lead author of "Primary Care Provider Experience With Proactive E-Consults to Improve COPD Outcomes and Access to Specialty Care<https://bit.ly/3CmlqAy>" in Chronic Obstructive Pulmonary Diseases. DOM co-authors are William Weppner, Rosemary Adamson, Douglas Berger, Karin Nelson, Paula Carvalho, Lucas Donovan, Laura Feemster, and David Au.


In the news
Dr. Filippo Milano, associate professor (Medical Oncology) was interviewed by ASH Clinical News for "From Football to Blood: Filippo Milano, MD, PhD<https://bit.ly/3IkC6w7>."

Dr. Jordan Prutkin, professor (Cardiology) is quoted in "University of Washington Doctors discuss Damar Hamlin's cardiac arrest<https://bit.ly/3Zac98n>" from KING 5 News.


Weekly Calendar, January 9-13, 2023
Our events calendar is posted on our website<https://medicine.uw.edu/news/trumba-calendar>.


Coming up
Gender Equity Lunch Series: Mentoring and Trailblazing
[cid:image055.jpg at 01D921E9.64EF9620]On Wednesday, Jan. 25, 2023, 12-1pm, the inaugural recipients of our Gender Equity Awards in Mentorship and Trailblazing - Dr. Stephanie Page, professor and head (Metabolism, Endocrinology and Nutrition), Dr. Michi Shinohara, professor (Dermatology) and the Internal Medicine Residency staff - will talk about their work. Led by guest moderators, the Gender Equity Lunch Series focuses on topics related to gender equity and leadership development. This series is open to all members of all genders in the Department of Medicine. Via Zoom<https://washington.zoom.us/j/92388076032>. Please register<https://forms.office.com/r/U5czH5CPeW> for this series.

Endocrinology and Diabetes Update for Primary Care
This comprehensive two-day course on endocrinology and diabetes is geared towards primary care providers. There is an immense need for education as the incidence of diabetes and endocrinology disorders in the general population, and primary care clinics carry the major burden of these patients. Didactic lectures offered in this program will provide the latest information on current topics related to diabetes, endocrinology, and guideline updates. Feb. 9-10. For more information and to register for this course, please visit the CME website<https://bit.ly/3GcklMH>.

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Amy Fields, Editor
amyf at uw.edu<mailto:amyf at uw.edu>


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