From domweek at u.washington.edu Fri Nov 4 16:53:27 2022 From: domweek at u.washington.edu (Department of Medicine weekly newsletter) Date: Fri Mar 22 11:23:13 2024 Subject: [domweek] DOM Week, November 7-11, 2022 Message-ID: [cid:image032.jpg@01D8F06D.F360D2A0] DOM Week November 4, 2022 News, information, and events of interest from the Department of Medicine (If you have items for DOM week, please email amyf@uw.edu) Awards [cid:image033.jpg@01D8F06D.F360D2A0]Dr. William Banks, professor (Gerontology and Geriatric Medicine) was honored with the Viktor Mutt lectureship award at the International Society for Bioactive Peptides meeting. The Viktor Mutt lectureship was established in recognition of the fundamental research of Viktor Mutt (1923-1998) in the field of gastrointestinal peptide hormones and neuropeptides. Dr. Banks was awarded for his outstanding work on the transportation of neuropeptides through the brain blood barrier and the study of their functional implication. ________________________________ [cid:image034.jpg@01D8F06D.F360D2A0]Physician Assistant of the Year Congratulations to Gabrielle Zecha, PA-C, MHA, associate medical director at Fred Hutchinson Cancer Center (FHCC) and teaching associate (Medical Oncology), who was awarded "Physician Assistant of the Year" by the Washington Academy of Physician Assistants last week at their annual conference. She was awarded this for her mentorship, leadership of the FHCC advanced practice providers through the turmoil of the last several years, and overall excellence as a physician assistant. Faculty news In memoriam: Deborah Kippen [cid:image035.jpg@01D8F06D.F360D2A0]Dr. Deborah Kippen passed away this summer at the age of 71. She helped build and was medical director of the Pioneer Square Clinic from 1982-1998. A trailblazer in expanding the rights of women health care providers in the University of Washington medical system, she worked to provide equal opportunities for working mothers and to increase the capacity for nurse practitioners to improve patient access. She also founded the first homeless medical respite program in Seattle, to provide a safe and clean place for homeless patients who were not sick enough to require overnight care in a hospital to recover from short-term health problems, such as minor trauma, chemotherapy treatments for cancer, and newly diagnosed chronic diseases. A memorial fund has been set up in honor of her vision, hard work, commitment to health equity, and her service as medical director of the Pioneer Square Clinic. All proceeds will go to the Pioneer Square Clinic and the care they provide their patients. For information on a memorial gathering, please contact Dr. Nancy Sugg at sugg@uw.edu. ________________________________ Save the date: Faculty promotion Q&A session Dr. Cynthia Ko, professor (Gastroenterology) and associate chair for faculty affairs, will be holding an informational session on faculty promotion processes and criteria on Wednesday, Nov. 30, from 12-1pm, via zoom (Meeting ID: 964 9512 4528, Passcode: 340340) Education news [Provider headshot ofJason F. Deen, MD]Prioritizing Native Health "It's been well documented that if a patient is cared for by a doctor who looks like them, is from their culture, and understands them and their family that they are more likely to trust that person and follow their recommendations," says Jason Deen, MD, FAAP (Blackfeet), associate professor of pediatrics and medicine (Cardiology) and vice chair for equity, diversity and inclusion in the Department of Pediatrics. Unfortunately, for many American Indians and Alaska Natives, it's difficult to find a doctor who understands their culture or background, in part, because there are so few Native physicians. Moreover, many people within these communities experience profound health inequities and face multiple systemic barriers to accessing the care they need. The Indian Health Pathway trains physicians to provide culturally humble care for Indigenous people. The first Native American to graduate from the UW School of Medicine, Dr. Walt Hollow, a member of the Assiniboine and Sioux Tribes, started the Indian Health Pathway in 1992, making it the longest running pathway at the School. "As an institution, we can augment the number of Indigenous physicians who are caring for these communities and augment the training of non-Native allies who are destined to work in Indian country," says Deen, who is also the current director of the Indian Health Pathway. Learn more from UW Medicine. ________________________________ Reconnection event Supporting the well-being of our community is one of our highest priorities, and why we started the pilot reconnect event seed funding program. The first group to reconnect was the IM residents in the Clinician Educator Pathway, who went curling! If you are interested in reconnecting, funds are still available to plan an event. [cid:image037.jpg@01D8F06D.F360D2A0] ________________________________ Clinical Research Methods course Fellows and junior faculty interested in clinical research are invited to join a fast-paced comprehensive online course in clinical research methods. Co-sponsored by the Department of Medicine and the Department of Pediatrics, this 11-week course will teach fundamental concepts in epidemiology and biostatistics and apply these methods toward the interpretation of articles from the published literature. Dr. Bryan Kestenbaum, professor (Nephrology) is the course director. For more information, please visit our website. Research news Breast cancer vaccine safely generates anti-tumor immunity [cid:image038.jpg@01D8F06D.F360D2A0]An experimental vaccine against breast cancer safely generated a strong immune response to a key tumor protein, according to a recent report published in JAMA Oncology. The findings suggest the vaccine may be able to treat different types of breast cancer. "Because this was not a randomized clinical trial, the results should be considered preliminary, but the findings are promising enough that the vaccine will now be evaluated in a larger, randomized clinical trial," said lead author Dr. Mary (Nora) Disis, professor (Medical Oncology), and director of the Cancer Vaccine Institute The phase I trial was designed to evaluate the safety of a vaccine that targets a protein called human epidermal growth factor receptor 2 (HER2) and to see if it generated an immune response to the protein. Read the full story from UW Medicine Newsroom. ________________________________ Complexity of diagnosing and managing long COVID [cid:image039.jpg@01D8F06D.F360D2A0]A study of veterans showed great uncertainty about whether to attribute symptoms to long COVID or to patients' other existing conditions. The study, published this week in JAMA Network Open, examined a national random sample of veterans with prior COVID infection and a diagnostic code for long COVID. The researchers' qualitative analysis of electronic health records showed frequent substantial clinical uncertainty about whether patients' symptoms stemmed from long COVID or from their other health conditions, explained Dr. Ann O'Hare, professor (Nephrology) and principal investigator with the VA COVID-19 Observational Research Collaboratory. "This (uncertainty) typically led to additional diagnostic testing and specialist referral, which could lead to fragmented and potentially burdensome care," O'Hare said. Read more on our news site. ________________________________ Machine learning analysis of right heart failure after left ventricular assist device implantation [cid:image040.jpg@01D8F06D.F360D2A0]For decades, left ventricular-assist devices (LVADs) have extended the lives of people whose hearts have grown too weak to effectively pump blood to the body. For upward of 20% of those patients, though, an LVAD implant gives rise to a dreaded complication: Their right ventricle fails, typically within days. Knowing beforehand which patients are at a higher risk to develop right-heart failure might enable doctors to reduce that likelihood. Researchers reported findings this week of a machine-learning analysis of 186 pre-implant patient factors, revealing the 30 most strongly associated with right-heart failure among a population of 19,595 first-time LVAD recipients. "We had two objectives with this study: to help predict which patients will develop this complication and to find out if there are factors we can optimize to lower the risk of right-heart failure before we implant the LVAD," said Dr. Song Li, a heart failure cardiologist at the UW Medicine Heart Institute and the paper's senior author. Lead author is Dr. Arjun Bahl, R3. Read the full story from UW Medicine Newsroom. ________________________________ Spatiotemporal high-resolution prediction of wildfire smoke exposure: Leveraging satellite remote sensing and low-cost sensor data [cid:image041.jpg@01D8F06D.F360D2A0]Wildfire activity has significantly increased over the past decades, including in the western U.S. However, a major impediment to comprehensive epidemiological and environmental justice analyses regarding wildfire smoke is the lack of accurate exposure estimates. Dr. Joel Kaufman, professor (General Internal Medicine) is part of the team that has received funding from the UW Population Health Initiative 2022 pilot research grant program. Their pilot study aims to build a "proof-of-concept" framework for spatiotemporally high-resolution wildfire PM2.5 exposure estimates (1 km, daily-level) in Washington. These future large-scale wildfire smoke data will serve as the foundation of extensive community-based applications and population-based health research. ________________________________ [Christopher W. Peterson] Dr. Christopher Peterson, research associate professor (Medical Oncology) has received an R01 for his project, "Developing Durable, Env-Boosted CAR T Cells for HIV Cure." Recent publications Dr. Maralyssa Bann, assistant professor (General Internal Medicine) is lead author of "Implementing a Social Determinants of Health Curriculum in Undergraduate Medical Education: A Qualitative Analysis of Faculty Experience" in Academic Medicine. Dr. Lauren Beste, associate professor (General Internal Medicine) is senior author of "Hepatitis B Virus-related Care Quality in Patients With Hepatitis B/Human Immunodeficiency Virus Coinfection Versus Hepatitis B Monoinfection: A National Cohort Study" in Clinical Infectious Diseases. Dr. Shailender Bhatia, professor (Medical Oncology) is co-author of "Combination of the STING Agonist MIW815 and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-label, Multicenter, Phase Ib Study" in Clinical Cancer Research. Dr. Benjamin Freedman, associate professor (Nephrology) is co-author of "Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease" in Nature Genetics. Dr. Matthew Golden, professor, is lead author and Dr. Judith Wasserheit, professor (Allergy and Infectious Diseases) is senior author of "Monkeypox - A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity" in the New England Journal of Medicine. Dr. Geoffrey Gottlieb, professor (Allergy and Infectious Diseases) is co-author of "Effect of Human Immunodeficiency Virus Infection on Human Papillomavirus Clearance among Women in Senegal, West Africa" in the Journal of Infectious Diseases. Dr. George Ioannou, professor (Gastroenterology) is co-author of "Mitochondrial dysfunction reactivates ?-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models" in JCI. Dr. Andrew Portuguese, fellow (Hematology) is lead author, and Dr. Hans Joachim Deeg, professor (Medical Oncology) is senior author of "Transplantation for myeloid neoplasms with antecedent solid tumor" in Cancer. DOM co-author is Aya Albittar. Dr. Alison Roxby, associate professor (Allergy and Infectious Diseases) is senior author of "Starting to have sexual intercourse is associated with increases in cervicovaginal immune mediators in young women: a prospective study and meta-analysis" in eLife. DOM co-authors are Anna Wald and Florian Hladik. Dr. Judith Tsui, professor (General Internal Medicine) is senior author of "Qualitative inquiry into perceptions of HIV pre-exposure prophylaxis among people who inject drugs living with hepatitis C in Seattle, WA, USA" in Harm Reduction Journal. DOM co-authors are Elenore Bhatraju, Sara Glick, Joanne Stekler and Alexander Gojic. In the news Dr. Anthony Back, professor (Medical Oncology) is quoted in "Single Dose of Synthetic 'Magic Mushroom' Psilocybin Eases Severe Depression" in Healthline. Dr. Helen Chu, associate professor (Allergy and Infectious Diseases) is quoted in "Treatment approved in Europe to prevent RSV in infants could be coming to the US soon" in CNN Health. Dr. Seth Cohen, clinical associate professor (Allergy and Infectious Diseases) is quoted in "Bivalent booster protects against omicron mutations ahead of winter" in MyNorthwest. Dr. Nancy Davidson, professor and head (Medical Oncology) is quoted in "Year in Review: Breast Cancer-Practice-changing therapy for HER2-low breast cancer, potential for some women to skip surgery" in Medpage Today. Dr. Andrew Luks, professor (Pulmonary, Critical Care and Sleep Medicine) is quoted in "Pulse oximeters and their inaccuracies will get FDA scrutiny today. What took so long?" in STAT. Events of interest Gender Equity Lunch Series: Gender and the Electronic Health Record workload [cid:image043.jpg@01D8F06D.F360D2A0]Special guest moderator, Dr. Eve Rittenberg, Harvard Medical Center, will discuss gender and the EHR workload, and her article "Primary Care Physician Gender and Electronic Health Record Workload" published in the Journal of General Internal Medicine. Eve Rittenberg, MD, is an assistant professor of medicine at Harvard Medical School and a primary care internist at the Fish Center for Women's Health at Brigham and Women's Hospital. Her interests include women's health, trauma-informed care, and health equity. Nov. 8, 12-1pm, via zoom (meeting ID: 935 5123 6119). Please RSVP. Weekly Calendar, November 7-11, 2022 Our events calendar is posted on our website. Coming up Gender Equity reconnection events The Department of Medicine Gender Equity Council is hosting a series of reconnection events. The purpose of these events is to meet new people and reconnect with colleagues in the department. These events will be held at different sites as a way for people at each location to meet each other and make new connections. Stop by at any time for donuts and coffee - all genders are welcome! * VA, Nov. 15, 12-1pm, Bldg. 1, Rm. 240 * HMC, Nov. 16, 1-2pm, 3WH 108 * UWMC-ML, Nov. 18, 11am-12pm, RR-110 Current concepts in medication therapy This CME conference will highlight innovation in drug therapies, review new indications for old medications, and discuss medication side effects and drug interactions. Speakers include DOM faculty from Allergy and Infectious Diseases, Cardiology, Gastroenterology, General Internal Medicine, Metabolism, Endocrinology and Nutrition, and Pulmonary, Critical Care and Sleep Medicine. Dec. 12-13. For more information and to register, please visit the CME website. ________________________________ Amy Fields, Editor amyf@uw.edu [cid:image002.jpg@01CF4461.CA7ADDC0] [YouTube_Logo_svg.png] [cid:image046.jpg@01D8F06D.F360D2A0] To subscribe/unsubscribe from this list, go to: https://mailman1.u.washington.edu/mailman/listinfo/domweek ________________________________ Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, reproduce, distribute, disseminate or otherwise use this transmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of the message and any attachments. -------------- next part -------------- An HTML attachment was scrubbed... URL: -------------- next part -------------- A non-text attachment was scrubbed... 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Name: image045.png Type: image/png Size: 6568 bytes Desc: image045.png URL: -------------- next part -------------- A non-text attachment was scrubbed... Name: image046.jpg Type: image/jpeg Size: 914 bytes Desc: image046.jpg URL: From domweek at u.washington.edu Thu Nov 10 16:16:43 2022 From: domweek at u.washington.edu (Department of Medicine weekly newsletter) Date: Fri Mar 22 11:23:14 2024 Subject: [domweek] DOM Week, November 14-18, 2022 Message-ID: [cid:image024.jpg@01D8F51F.CFCE1350] DOM Week November 10, 2022 News, information, and events of interest from the Department of Medicine (If you have items for DOM week, please email amyf@uw.edu) First Gen Students and Faculty Share Their Stories [cid:image025.jpg@01D8F51F.CFCE1350]Nov. 8 was National First-Generation Day, a time to recognize the challenges and celebrate the successes of first-generation students, faculty and staff, or individuals whose parents did not receive a baccalaureate degree. UW School of Medicine faculty, residents, fellows and students - including Drs. Hao Tong, chief resident, Sofia Jaramillo Quiroz, fellow (Gerontology and Geriatric Medicine) and Johnnie Orozco, associate professor (Medical Oncology) - shared with The Huddle what being first generation means to them. Awards Health Care Leadership Lifetime Achievement Award [cid:image026.jpg@01D8F51F.CFCE1350]Dr. Larry Corey, professor (Allergy and Infectious Diseases) is the 2022 recipient of the Health Care Leadership Lifetime Achievement Award from the Puget Sound Business Journal. For more than four decades, Dr. Corey has led some of the most significant advances in medicine, including the development of safe and effective antivirals for herpes, HIV and hepatitis infections. ________________________________ Washington Chapter ACP Awards Congratulations to the following DOM faculty who received awards at the recent American College of Physicians (ACP) Washington state chapter meeting: * Dr. Matthew Hollon, clinical professor, Laureate Award * Dr. Michael Kerkering, clinical instructor, Full-time Faculty Clinician-Educator of the Year Award * Dr. Rachel Safran, clinical assistant professor, Golden Apple Award [cid:image027.jpg@01D8F51F.CFCE1350] Read more on our news site. ________________________________ Call for nominations: William J. Bremner Endowed Mentorship Awards There's still time to nomination your colleagues for the William J. Bremner Endowed Mentorship Awards. These awards honor faculty members for their contribution to the scientific, educational, and patient care missions of the Department of Medicine through exemplary mentorship. Two awards are given annually: (1) Excellence in Mentorship of Physician-Scientists and (2) Excellence in Mentorship of Clinician-Scholars or Full-time Clinical Faculty. Nominations are due Nov. 14. For more information, please visit our website. Faculty news [cid:image028.jpg@01D8F51F.CFCE1350]Dr. Ajay Gopal, professor (Medical Oncology) has been appointed to the Stephen Hans Petersdorf, MD Endowed Chair in Cancer Care. This chair was created to support the work of an outstanding clinician and teacher whose primary interest is the clinical care of cancer patients. Dr. Gopal is the medical director of clinical research for hematology malignancies at Fred Hutch Cancer Center. His research specializes in lymphomas and other cancers of the blood, and develops new targeted treatments for patients with lymphoma. ________________________________ Jumpstart communication priming tool [cid:image029.jpg@01D8F51F.CFCE1350]Dr. Erin Kross, associate professor (Pulmonary, Critical Care and Sleep Medicine) joins Collective Conversations to discuss her research experience in palliative care deploying a communication priming tool, the Jumpstart Guide, within outpatient and inpatient settings. Collective Conversations is a series of discussions aimed at highlighting people and groups working to improve health through better health care systems. Staff news [cid:image030.jpg@01D8F51F.CFCE1350]Glenda Roberts, director of external relations and patient engagement, Kidney Research Institute and Center for Dialysis Innovation (Nephrology) was selected as the 2022 Accelerate Innovation spokesperson for United for Kidney Health, an awareness-building initiative led by the American Society of Nephrology (ASN) to educate nephrologists, other kidney health professionals, and scientists about the dramatic changes and new opportunities taking place in kidney care, research, and education, and enhance their professional development, and training. Research news Clinical outcomes vary across subtypes of pulmonary arterial hypertension [cid:image031.jpg@01D8F51F.CFCE1350]A recent study examined how markers of inflammation and angiogenesis in patients with pulmonary arterial hypertension were related to clinical outcomes across disease subtypes. This was a translational retrospective study that explored how cytokine levels were associated with mortality, and how the strength of those connections depended on specific disease subtypes. "While patients with pulmonary arterial hypertension are often grouped together in clinical trial regardless of their subtype, our findings support that a more subtype specific focus may be warranted," said Dr. Kellen Hirsch, R3, and lead author on the paper, published in the Journal of Heart and Lung Transplant. Learn more on our news site. Recent publications Drs. Nisha Bansal, professor (Nephrology) and David Garcia, professor (Hematology) are co-authors of "Apixaban for Patients with Atrial Fibrillation on Hemodialysis: A Multicenter Randomized Controlled Trial" in Circulation. Dr. Richard Cheng, associate professor (Cardiology) is co-author of "Toward a Better Understanding of the Differential Impact of Heart Failure Phenotypes After Breast Cancer" in the Journal of Clinical Oncology. Dr. Jason Dominitz, professor (Gastroenterology) is co-author of "The Association Between Nonsteroidal Anti-Inflammatory Drug Use and Inflammatory Bowel Disease Exacerbations: A True Association or Residual Bias?" in the American Journal of Gastroenterology. Dr. Emily Ford, assistant professor, is lead author, and Dr. Larry Corey, professor (Allergy and Infectious Diseases) is senior author of "Successful treatment of prolonged, severe COVID-19 lower respiratory tract disease in a B-cell ALL patient with an extended course of remdesivir and nirmatrelvir/ritonavir" in Clinical Infectious Diseases. DOM co-authors are William Simmons, Ellora Karmarkar, Leah Yoke, Ayodale Braimah, Johnnie Orozco, Cristina Ghiuzeli, Serena Barnhill, Coralynn Sack, Joshua Benditt, Adrienne Shapiro, Michael Boeckh, Catherine Liu, and Guang-Shing Cheng. Dr. William Gwim, assistant professor (Medical Oncology) is co-author of "Margetuximab Versus Trastuzumab in Patients With Previously Treated HER2-Positive Advanced Breast Cancer (SOPHIA): Final Overall Survival Results From a Randomized Phase 3 Trial" in the Journal of Clinical Oncology. Drs. Grace John-Stewart, professor, and Judd Walson, professor (Allergy and Infectious Diseases) are co-authors of "Cytomegalovirus Viremia Predicts Postdischarge Mortality in Kenyan HIV-Exposed Uninfected Children" in the Journal of Infectious Diseases. Dr. Charles Landis, associate professor (Gastroenterology) is co-author of "A Randomized, Dose-Finding, Proof-of-Concept Study of Berberine Ursodeoxycholate in Patients With Primary Sclerosing Cholangitis" in the American Journal of Gastroenterology. Dr. Despoina Michailidou, fellow, is lead author, and Dr. Bernard Ng, associate professor (Rheumatology) is senior author of "Predictive models for thromboembolic events in giant cell arteritis: A US veterans health administration population-based study" in Frontiers in Immunology. DOM co-author is Gary Lyman. Dr. Katherine Tuttle, clinical professor (Nephrology) is co-author of "Empagliflozin in Patients with Chronic Kidney Disease" in the New England Journal of Medicine. In the news Dr. David Au, professor (Pulmonary, Critical Care and Sleep Medicine) is quoted in "FDA Panel Backs Novel Combination Inhaler for Asthma in Adults Only- Agency advisors reject budesonide-albuterol sulfate inhaler for children, split on adolescents" in MedPage Today. Dr. Seth Cohen, clinical associate professor (Allergy and Infectious Diseases) is quoted in "9 Ways to Make Holiday Gatherings Safer During COVID-19 Times" in Everyday Health. Dr. Eric Larson, clinical professor (General Internal Medicine) is quoted in "Aging Expert Reveals How Retirees Can Live A Healthy, Happier Life" in Forbes. Events of interest Gender Equity reconnection events The Department of Medicine Gender Equity Council is hosting a series of reconnection events. The purpose of these events is to meet new people and reconnect with colleagues in the department. These events will be held at different sites as a way for people at each location to meet each other and make new connections. Stop by at any time for donuts and coffee - all genders are welcome! * VA, Nov. 15, 12-1pm, Bldg. 1, Rm. 240 * HMC, Nov. 16, 1-2pm, 3WH 108 * UWMC-ML, Nov. 18, 11am-12pm, RR-110 ________________________________ Medicine Grand Rounds Dr. Andrew Stergachis (Medical Genetics) will present the Fialkow Scholars Award Presentation: "Moving into the unknown: the next stage of genetics and genomics" at Medicine Grand Rounds on Friday, November 18, 2022,12-1pm, via zoom. Weekly Calendar, November 14-18, 2022 Our events calendar is posted on our website. Coming up Faculty promotion Q&A session Dr. Cynthia Ko, professor (Gastroenterology) and associate chair for faculty affairs, will be holding an informational session on faculty promotion processes and criteria on Wednesday, Nov. 30, from 12-1pm, via zoom (Meeting ID: 964 9512 4528, Passcode: 340340) Current concepts in medication therapy This CME conference will highlight innovation in drug therapies, review new indications for old medications, and discuss medication side effects and drug interactions. Speakers include DOM faculty from Allergy and Infectious Diseases, Cardiology, Gastroenterology, General Internal Medicine, Metabolism, Endocrinology and Nutrition, and Pulmonary, Critical Care and Sleep Medicine. Dec. 12-13. For more information and to register, please visit the CME website. ________________________________ Amy Fields, Editor amyf@uw.edu [cid:image002.jpg@01CF4461.CA7ADDC0] [YouTube_Logo_svg.png] [cid:image034.jpg@01D8F51F.CFCE1350] To subscribe/unsubscribe from this list, go to: https://mailman1.u.washington.edu/mailman/listinfo/domweek ________________________________ Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, reproduce, distribute, disseminate or otherwise use this transmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of the message and any attachments. -------------- next part -------------- An HTML attachment was scrubbed... URL: -------------- next part -------------- A non-text attachment was scrubbed... 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Name: image034.jpg Type: image/jpeg Size: 913 bytes Desc: image034.jpg URL: From domweek at u.washington.edu Fri Nov 18 16:44:01 2022 From: domweek at u.washington.edu (Department of Medicine weekly newsletter) Date: Fri Mar 22 11:23:14 2024 Subject: [domweek] DOM Week, November 21-25, 2022 Message-ID: [cid:image026.jpg@01D8FB6C.F3F32E70] DOM Week November 18, 2022 News, information, and events of interest from the Department of Medicine (If you have items for DOM week, please email amyf@uw.edu) Awards [cid:image027.jpg@01D8FB6C.F3F32E70]Outstanding Research Mentor Awards Nominated by students throughout WWAMI, 8 mentors were selected by the School of Medicine Scholarship Committee to receive Outstanding Research Mentor Awards, including the following from the Department of Medicine: Dr. Cory Simpson, assistant professor (Dermatology) and Dr. Namrata Singh, assistant professor (Rheumatology). ________________________________ [cid:image028.jpg@01D8FB6C.F3F32E70]King County Medical Society Foundation Awards Congratulations to the following who received King County Medical Society Foundation Awards: Dr. Anita Chopra, clinical instructor (General Internal Medicine) received the Reducing Health Disparities Award; Dr. Jeffrey Duchin, professor (Allergy and Infectious Diseases) received the Public Health Achievement Award; and Dr. Sabine von Preyss-Friedman, clinical associate professor emeritus (Gerontology and Geriatric Medicine) received the Covid-19 Leadership Award. Faculty news Examining genetics and genomics workforce diversity [cid:image029.jpg@01D8FB6C.F3F32E70]Dr. Fuki Hisama, professor (Medical Genetics) was on the American College of Medical Genetics and Genomics (ACMG) Workforce Diversity Initiative Advisory Group that assessed diversity in the medical genetics workforce. The ACMG joined major genetics and genomics organizations in releasing the Human Genetics & Genomics Workforce Survey Report. ?A diverse genetics workforce is key to realizing the benefits of medical genetics for everyone,? she said. ?This survey is a major milestone toward advancing the ACMG mission and the key findings will help identify opportunities to improve recruitment, training and retention efforts.? Dr. Hisama has also been named the inaugural section editor for clinical genetics for Genetics in Medicine Open, a new open access journal of the American College of Medical Genetics and Genomics, launching in January 2023. ________________________________ [cid:image030.jpg@01D8FB6C.F3F32E70] Dr. Paul Nghiem, professor and head (Dermatology) delivered the fifteenth annual Rodan-Fields Lecturer in Dermatology at Stanford last week. He presented ?Merkel cell carcinoma: An often-lethal, virus-driven cancer provides insights into adaptive and innate anti-tumor immunity.? Education news Call for mentors and coaches for residents from underrepresented backgrounds The Internal Medicine Resident Diversity Committee (RDC) is looking for mentors/career coaches. They would like to create an active list of faculty members and their associated clinical and research interests that can be used by RDC members to find someone with whom they may be able to connect. The goal would be to better link residents with faculty members that share their diverse backgrounds and/or diverse clinical and research interests. Faculty members linked with residents would be able to provide professional advice and guidance, or potentially consider collaboration on research projects. The RDC would like to create this list with a goal, in part, of getting faculty recognition for the time and effort that they contribute to this activity. If you are interested, please complete this form. ________________________________ Call for applications: Palliative care research fellowship Applications are now being accepted for the Cambia Palliative Care Center of Excellence palliative care research fellowship. This post-doctoral research fellowship is funded by a T32 Training Grant Award from the National Heart, Lung, and Blood Institute and designed for post-doctoral fellows interested in a 1-2 year fellowship to learn to conduct palliative care research. Applications are due Dec. 15 for positions to start in 2023. Please feel free to share with people you think may be interested in this opportunity. More information about the fellowship program can be found on their website. Clinical news Meeting the needs of people facing winter homelessness [cid:image031.jpg@01D8FB6C.F3F32E70]Cold weather brings dire consequences to the unhoused. Drs. Leslie Enzian and Darrell Owens care for those experiencing homelessness. For 27 years, Enzian has worked as a primary care provider for people experiencing homelessness at UW Medicine Pioneer Square Clinic. She has also been the medical director at the Edward Thomas House Medical Respite since 1996. Owens has practiced hospice and palliative care for 30 years. His work focuses on the symptoms that impact the quality of life, including physical or emotional pain, and guiding patients through difficult decision making processes. Read the full story from the Seattle Medium. Research news Award will fund research into new metastatic prostate cancer therapies [cid:image032.png@01D8FB6C.F3F32E70]For about 70 years, prostate cancer researchers have known that the male sex hormone testosterone, an androgen, along with androgen receptor signaling on prostate cancer cells, are linked to survival rates in prostate cancer. ?We?ve been really effective at blocking that hormone, that target, in prostate cancer,? said Dr. John Lee, assistant professor (Medical Oncology). ?But it?s not a cure, not in metastatic disease. It will make the disease regress and be controlled for a couple of years, but eventually the prostate cancer will figure out a way to keep going, independent of androgens and sometimes independent of androgen receptors.? A three-year, $750,000 grant from the San Antonio, Texas-based Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation will allow Lee and Fred Hutch collaborators Drs. Pete Nelson and Roland Strong to explore new treatment options, specifically through the use of immunotherapy. Learn more from Hutch News. ________________________________ Highly cited researchers Congratulations to those who have been selected as Highly Cited Researchers from the Web of Science Group. Their work has been identified as being among the most valuable and significant in the field. Very few researchers earn this distinction ? writing the greatest number of reports, officially designated by Essential Science Indicators (ESI) as Highly Cited Papers. In addition, these reports rank among the top 1% most cited works for their subject field and year of publication in the Web of Science, earning them the mark of exceptional impact. 2022 DOM Highly Cited Researchers William Banks, Gerontology and Geriatric Medicine Michael Boeckh, Allergy and Infectious Diseases Gary Lyman, Medical Oncology David Maloney, Medical Oncology Peter Nelson, Medical Oncology Ganesh Raghu, Pulmonary, Critical Care and Sleep Medicine Stanley Riddell, Medical Oncology ________________________________ Kidney Disease: Improving Global Outcomes [cid:image033.jpg@01D8FB6C.F3F32E70]Dr. Ian de Boer, professor (Nephrology) co-chaired the Kidney Disease: Improving Global Outcomes (KDIGO) 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Diseases (CKD). The guideline is designed to apply to a broad population of patients with diabetes and CKD, while being mindful of implications for policy and payment. Type 1 and type 2 diabetes are both addressed, with differences in approach to management highlighted when appropriate. ________________________________ New in vivo approach to treat sickle cell disease [cid:image034.jpg@01D8FB6C.F3F32E70]Drs. Chang Li, research assistant professor, and Andr? Lieber, professor (Medical Genetics) recently met with former NIH Director Dr. Francis Collins, when he visited the University of Washington to discuss their new in vivo approach to treat Sickle Cell Disease (SCD) and beyond. They said they were impressed by how many details Collins already knew about their studies in the SCD mouse model. Li and Lieber provided Collins with a realistic idea about their approach, the potential, and the hurdles that need to be addressed. Learn more on our news site. ________________________________ Cystic Fibrosis Foundation Grants Several faculty members in the Division of Pulmonary, Critical Care and Sleep Medicine have received funding from the Cystic Fibrosis Foundation. Drs. Kathleen Ramos and Christopher Goss, in collaboration with Drs. Siddhartha Kapnadak, Eric Morrell and Erika Lease received a Leadership and Design Grant to support gathering preliminary data about the use of prophylactic azithromycin after lung transplant and determine the feasibility of a definitive multicenter clinical trial within the Cystic Fibrosis Lung Transplant Consortium. Drs. Christopher Goss and Pradeep Singh received $5.2 million for a new project titled, ?Standardizing Treatments for Pulmonary Exacerbations: A platform for evaluating treatment decisions to improve outcomes (STOP360)?. Dr. Pavan Bhatraju, co-investigator, will lead a sub-study evaluating antibiotic associated nephrotoxicity in participants in STOP360. Recent publications Dr. Helen Chu, associate professor (Allergy and Infectious Diseases) is co-author of ?Imprinted antibody responses against SARS-CoV-2 Omicron sublineages? in Science. Dr. Ann Collier, professor emeritus (Allergy and Infectious Diseases) is co-author of ?Proteomic Signature of Subclinical Coronary Artery Disease in People With HIV: Analysis of the REPRIEVE Mechanistic Substudy? in the Journal of Infectious Diseases. Drs. Laura Crisa, associate professor, is lead author, and Dr. Vincenzo Cirulli, associate professor (Metabolism, Endocrinology and Nutrition) is senior author of ?Bone marrow chimerism breaks the barrier to pancreatic islet transplantation? in Cell Reports. Dr. Mehraneh Khalighi, clinical associate professor, is lead author, and Dr. Paul Cornia, associate professor (General Internal Medicine) is senior author of ?Preoperative Insulin Intensification to Improve Day of Surgery Blood Glucose Control? in Federal Practitioner. Dr. Sylvia Lee, associate professor (Medical Oncology) is co-author of ?Non-viral precision T cell receptor replacement for personalized cell therapy? in Nature. Dr. A. McGarry Houghton, professor (Pulmonary, Critical Care and Sleep Medicine) is senior author of ?Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils? in JCI. Dr. Ganesh Raghu, professor (Pulmonary, Critical Care and Sleep Medicine) is senior author of ?Quantitative computed tomography of the chest for fibrotic lung diseases: Prime time for its use in routine clinical practice?? in Respirology and lead author of ?Randomized Phase IIa Clinical Study of an Anti-?v?6 Monoclonal Antibody in Idiopathic Pulmonary Fibrosis? and ?A Phase IIb Randomized Clinical Study of an Anti-?v?6 Monoclonal Antibody in Idiopathic Pulmonary Fibrosis? in the American Journal of Respiratory and Critical Care Medicine. Dr. Mazyar Shadman, associate professor (Medical Oncology) is lead author of ?Zanubrutinib in patients with previously treated B-cell malignancies intolerant of previous Bruton tyrosine kinase inhibitors in the USA: a phase 2, open-label, single-arm study? in Lancet Haematology. Dr. Rashmi Sharma, associate professor (General Internal Medicine) is co-author of ?Racism in Palliative Care Research: We Still have a Ways to Go? in the Journal of Pain and Symptom Management. In the news Drs. John Amory, professor (General Internal Medicine) and Stephanie Page, professor and head (Metabolism, Endocrinology and Nutrition) are quoted in ?After decades of setbacks, scientists make strides toward the holy grail of male birth control? in STAT. Dr. Martha Billings, associate professor (Pulmonary, Critical Care and Sleep Medicine) is quoted in ?Why You Wake Up in the Night (And How to Stop)? from Right as Rain. Dr. Rotonya Carr, associate professor and head (Gastroenterology) is quoted in ?In armadillos, leprosy expands healthy liver tissue. Could that tell us something about regenerating our own?? in STAT. Dr. Mary (Nora) Disis, professor (Medical Oncology) is quoted in ?Breast cancer vaccine shows promise in early trial? in The Hill: Changing America. Dr. Irl Hirsch, professor (Metabolism, Endocrinology and Nutrition) is quoted in ?Insulin used to be affordable ? and then, seemingly out of nowhere, it wasn't. Why?? in Salon. Dr. Douglas Paauw, professor (General Internal Medicine) wrote ?How Can I Keep From Losing My Mind?? for Medscape. Dr. Coralynn Sack, assistant professor (General Internal Medicine) is quoted in ?What the Air Quality Index doesn't tell us about smoke dangers? in Crosscut. Dr. Ellen Schur, professor (General Internal Medicine) wrote the blog post ?Ask a Doctor: Why am I always hungry?? in the Washington Post. Weekly Calendar, November 21-25, 2022 Our events calendar is posted on our website. Coming up Faculty promotion Q&A session Dr. Cynthia Ko, professor (Gastroenterology) and associate chair for faculty affairs, will be holding an informational session on faculty promotion processes and criteria on Wednesday, Nov. 30, from 12-1pm, via zoom (Meeting ID: 964 9512 4528, Passcode: 340340) Current concepts in medication therapy This CME conference will highlight innovation in drug therapies, review new indications for old medications, and discuss medication side effects and drug interactions. Speakers include DOM faculty from Allergy and Infectious Diseases, Cardiology, Gastroenterology, General Internal Medicine, Metabolism, Endocrinology and Nutrition, and Pulmonary, Critical Care and Sleep Medicine. Dec. 12-13. For more information and to register, please visit the CME website. ________________________________ Amy Fields, Editor amyf@uw.edu [cid:image002.jpg@01CF4461.CA7ADDC0] [YouTube_Logo_svg.png] [cid:image037.jpg@01D8FB6C.F3F32E70] To subscribe/unsubscribe from this list, go to: https://mailman1.u.washington.edu/mailman/listinfo/domweek ________________________________ Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, reproduce, distribute, disseminate or otherwise use this transmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of the message and any attachments. -------------- next part -------------- An HTML attachment was scrubbed... URL: -------------- next part -------------- A non-text attachment was scrubbed... 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[image018.jpg] DOM Week November 23, 2022 News, information, and events of interest from the Department of Medicine (If you have items for DOM week, please email amyf@uw.edu) Awards U.S. Presidential Volunteer Service Awards [image019.jpg]Dr. Jonathan Himmelfarb, professor, and Glenda Roberts, director of external relations and patient engagement (Nephrology) have been recognized by President Joseph R. Biden with U.S. Presidential Volunteer Service Awards. They both received gold medals. In 2003, the President?s Council on Service and Civic Participation founded the President?s Volunteer Service Award to recognize the important role of volunteers in America?s strength and national identity. This award honors individuals whose service positively impacts communities in every corner of the nation and inspires those around them to take action, too. Learn more on our news site. ________________________________ Call for nominations: Excellence in Global Engagement Award The Excellence in Global Engagement Award is a new annual award that honors faculty and staff at the UW for their leadership in global engagement. The award will alternate each year between faculty and staff honorees. The inaugural award will honor a UW faculty member. The award focuses on teaching, research, and/or community building activities that connect UW students, faculty, and staff to global communities locally, nationally, and internationally. The award is the highest recognition for UW faculty and staff who make significant contributions to global engagement at the UW and carries a $5,000 stipend. Nominations are due Dec. 16. Reminder: Also due on Dec. 16 are nominations for the Distinguished Staff Awards and David B. Thorud Leadership Award. EDI news Call for applications: Diversity Seed Grants The Vice President for Minority Affairs & Diversity and University Diversity Officer is pleased to offer Diversity and Inclusion Seed Grants. These small grants support projects for institutional transformation across the University of Washington?s tri-campus community that align with the goals of the 2022-2026 UW Diversity Blueprint. The six goals of the Diversity Blueprint are: * Cultivate an Accessible, Inclusive, and Equitable Campus Climate * Attract, Retain, and Graduate a Diverse and Excellent Student Body * Attract and Retain Diverse Academic Personnel * Attract and Retain Diverse Staff * Develop Place-Based Education and Engagement to Advance Access, Inclusion and Equity * Improve Accountability and Transparency at All Levels Proposals are accepted twice annually. The fall deadline is Dec. 16. For more information, please visit their website. Faculty news [image020.jpg]Dr. Mazyar Shadman, associate professor (Medical Oncology) has been appointed co-chair of the Lymphoma Working Committee for the Center for International Blood & Marrow Transplant Research (CIBMTR). The Lymphoma Working Committee provides scientific oversight for studies related to hematopoietic cell transplantation for Hodgkin and non-Hodgkin disease. Education news Healing through humanity [image021.jpg]Dr. Justin Bullock, fellow (Nephrology) gave the 2022 American Academy of Pediatrics (AAP) Plenary Session, ?I?m Just Trying to Survive: A Story of Healing Through Humanity.? Through the lens of his relationship with his therapist, he examined how health care providers can leverage humanity in clinical practice in ways that can be lifesaving; discussed his experiences as a bipolar patient and physician, including his psychiatric hospitalizations and suicide attempts during training; and described his efforts to change the culture in medical education and training so they are more supportive and inclusive of those with mental illness. Clinical news Department of Medicine Health Systems Collective: Data Asset Offerings Earlier this year, the Department of Medicine announced the Health Systems Collective, an initiative aimed at supporting people and groups in DOM interested in improving health through systems of care. The Collective seeks to do so by providing a set of resources and services to DOM members. This includes access to data assets that can be used to answer important care delivery and systems questions. Information about more data assets will be added to this website as they become available. Please contact the Health Systems team with any questions or subscribe to be added to future announcements from the Collective. Research news Breast cancer research foundation grants [image022.jpg]Dr. Nancy Davidson, professor and head (Medical Oncology) received funding to pursue a new research project involving PARP inhibitors. Dr. Mary (Nora) Disis, professor (Medical Oncology) received funding to continue her work on a vaccine designed to address obesity, an important risk factor for breast cancer, particularly when it comes to women with metabolic syndrome and metabolic dysfunction. Dr. Mary-Claire King, professor (Medical Genetics) received funding to adapt rapidly evolving genomic technology to sequence large swaths of DNA in single very long strands, rather than thousands of short bits, and to explore dysregulation of gene expression as a basis for inherited breast cancer. Dr. Hannah Linden, professor (Medical Oncology) received funding to lead the first multi-center study to test the accuracy of FFNP-PET for predicting response to endocrine therapy. Drs. Christopher Li and Anne McTiernan (Epidemiology) also received BCRF grants. Read the full story from Hutch News. Recent publications Dr. Rachel Bender Ignacio, assistant professor (Allergy and Infectious Diseases) is lead author of ?Dynamic immune markers predict HIV acquisition and augment associations with sociobehavioral factors for HIV exposure? in iScience. Joy Lee, research coordinator, and Dr. Joshua Liao, associate professor (General Internal Medicine) and associate chair, are co-authors of ?Meta-summaries effective for improving awareness and understanding of COVID-19 vaccine safety research? in Nature Scientific Reports. Dr. Christine Limonte, clinician researcher, is lead author, and Dr. Ian de Boer, professor (Nephrology) is senior author of ?Effects of vitamin D3 supplementation on cardiovascular and cancer outcomes by eGFR in VITAL? in Kidney 360. DOM co-author is Leila Zelnick. Dr. Graham Nichol, professor (General Internal Medicine) is lead author of ?Contemporary Approaches to Reducing Morbidity and Mortality in Patients With Acute Coronary Syndromes? in the Journal of the American College of Cardiology, and senior author of ?A Commentary on the Effect of Targeted Temperature Management in Patients Resuscitated from Cardiac Arrest? in Therapeutic Hypothermia and Temperature Management. DOM co-authors are Jeanne Poole and Ken Fujise. Drs. Pandora Wander, assistant professor (General Internal Medicine), George Ioannou, professor (Gastroenterology), Edward Boyko, professor (General Internal Medicine) and Ann O?Hare, professor (Nephrology) are co-authors of ?Consensus elements for observational research on COVID-19-related long-term outcomes? in Medicine. In the news Dr. Helen Chu, associate professor (Allergy and Infectious Diseases) talked to KUOW in ?'Tis the season for respiratory illness.? Dr. Michael Myint, clinical associate professor (Allergy and Infectious Diseases) is quoted in ?Long Covid Changed her life forever? in Healthy Woman. Dr. Steven Pergam, associate professor (Allergy and Infectious Diseases) is quoted in ?Immunocompromised Health Experts Are Approaching the Holidays? in the New York Times. Dr. Coralynn Sack, assistant professor (General Internal Medicine) is quoted in ?What the Air Quality Index doesn?t tell us about smoke dangers? in The Columbian. Events of interest Faculty promotion Q&A session Dr. Cynthia Ko, professor (Gastroenterology) and associate chair for faculty affairs, will be holding an informational session on faculty promotion processes and criteria on Wednesday, Nov. 30, from 12-1pm, via zoom (Meeting ID: 964 9512 4528, Passcode: 340340) Weekly Calendar, November 28-December 2, 2022 Our events calendar is posted on our website. Coming up Current concepts in medication therapy This CME conference will highlight innovation in drug therapies, review new indications for old medications, and discuss medication side effects and drug interactions. Speakers include DOM faculty from Allergy and Infectious Diseases, Cardiology, Gastroenterology, General Internal Medicine, Metabolism, Endocrinology and Nutrition, and Pulmonary, Critical Care and Sleep Medicine. Dec. 12-13. For more information and to register, please visit the CME website. ________________________________ Amy Fields, Editor amyf@uw.edu [image023.jpg] [image024.png] [image025.jpg] To subscribe/unsubscribe from this list, go to: https://mailman1.u.washington.edu/mailman/listinfo/domweek ________________________________ Privileged, confidential or patient identifiable information may be contained in this message. This information is meant only for the use of the intended recipients. If you are not the intended recipient, or if the message has been addressed to you in error, do not read, disclose, reproduce, distribute, disseminate or otherwise use this transmission. Instead, please notify the sender by reply e-mail, and then destroy all copies of the message and any attachments. -------------- next part -------------- An HTML attachment was scrubbed... URL: -------------- next part -------------- A non-text attachment was scrubbed... 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